Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$150K - $180K *

Drive revenue growth by leading a high-performing enterprise sales team, executing strategic sales plans, and building relationships with key decision-makers in the cybersecurity sector. Collaborate c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Empower the clinical support team by coordinating complex cases, mentoring junior counselors, and enhancing protocols. Your expertise will drive effective communication and quality standards in geneti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $116K *

Elevate your career by joining a team that reviews and edits informed consent forms, ensuring compliance with regulatory standards while mentoring new editors and enhancing organizational knowledge in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $138K *

Manage regional meetings and events, ensuring seamless execution and compliance. Oversee budgets, vendor relationships, and logistics while collaborating with cross-functional teams to meet organizati...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive reputation management and consumer insights initiatives, enhancing brand trust and informing strategic decisions. Collaborate across teams to analyze data, identify trends, and improve consumer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $125K *

Transform coding quality and efficiency as a senior expert in radiology coding. Collaborate with cross-functional teams to enhance processes, provide guidance, and drive best practices, ensuring excep...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $135K *

Empower clinical research excellence by managing projects that ensure compliance with regulatory requirements and drive successful study delivery from initiation to closeout. Collaborate with interdis...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $185K *

Transform complex workflows by leading AI-driven change initiatives, guiding senior leaders through redesign and adoption processes, and ensuring measurable outcomes in legal, tax, and trade sectors...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$104K - $143K *

Deliver impactful reporting solutions by translating measurement needs into actionable requirements, managing backlogs, and collaborating with cross-functional teams to ensure effective execution and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $230K *

Champion the promotion of oncology products, building strong relationships with key stakeholders. Drive performance goals, manage territory effectively, and ensure patient access to treatments while e...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team to support product management for government insurance, ensuring compliance and driving strategic initiatives. Leverage your expertise to lead analysis, define requirements, and en...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $110K *

Shape the future of learning by leading innovative enablement programs that empower managers and new hires. Collaborate with cross-functional teams to design impactful training solutions that drive or...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $130K *

Partner with us to drive Major Incident Management, ensuring swift resolution and effective communication across teams. Leverage your expertise to enhance service restoration and support our hosted cu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $195K *

Unlock patient engagement strategies by integrating insights into drug development. Collaborate with diverse teams to generate evidence, engage with professional societies, and lead initiatives that p...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $190K *

Join a team that's dedicated to advancing precision medicine by leveraging AI to provide cutting-edge educational support and scientific expertise on cancer biomarker tests while engaging key opinion...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $201K *

Drive category strategy and supplier relationships to enhance Market Access, Pricing, and Health Economics. Collaborate with cross-functional teams to optimize procurement processes and improve operat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's driving transformative change through strategic analysis and execution. This high-visibility role collaborates with leadership to ensure progress on critical initiatives and enhance...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$200K - $230K *

Elevate data operations by architecting AI-driven solutions that enhance resilience, scalability, and intelligence in data processing systems. Lead cross-functional teams to implement innovative DataO...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$74K - $111K *

Join a team that's dedicated to delivering exceptional service through timely maintenance and repairs of medical equipment, ensuring optimal healthcare delivery while enhancing customer satisfaction a...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$105K - $157K *

Deliver exceptional service as a Field Engineer, resolving advanced technical issues and enhancing customer satisfaction. Collaborate with teams to drive service excellence and support business growth...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Help us deliver exceptional training and support for medical imaging equipment, enhancing customer experiences through expertise and mentorship while traveling frequently to engage with healthcare pro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in driving enterprise sales by managing the full sales cycle, engaging with large organizations, and expanding relationships within the AI sector. Your expertise will be pivotal in est...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$210K - $250K *

Shape the future of healthcare by leading a dynamic clinic team, enhancing patient care, and driving operational excellence in a collaborative environment. Enjoy a rewarding career with competitive co...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$295K - $314K *

Drive strategic biostatistical leadership for clinical development programs, overseeing statistical activities, collaborating with cross-functional teams, and ensuring high-quality data analysis to su...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.