Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
$210K - $249K *
Lead the vision and strategy for SRE across payments, driving reliability, automation, and incident management while scaling the function and fostering a culture of operational excellence and continuo...
1 week ago
$160K - $200K *
Drive technical excellence by designing systems, setting standards, and mentoring engineers without formal management. Collaborate with Product to ensure alignment and tackle engineering challenges ac...
Reposted 4 weeks ago
Director, Patient Access (Travel)
$92K - $125K *
Drive operational excellence in patient access by leading teams, enhancing processes, and fostering collaboration across healthcare facilities. Your leadership will ensure compliance, improve patient...
Yesterday
$125K - $150K *
Unlock potential by leading Health and VA claims operations, driving strategic initiatives, enhancing recovery outcomes, and ensuring operational excellence across multiple teams and client portfolios...
Yesterday
Senior Director, Early Oncology
$230K - $345K *
Transform clinical trial management by leading early-phase oncology programs. Drive strategic vision, operational excellence, and cross-functional collaboration to ensure timely, budget-compliant exec...
Yesterday
Clinical Operations Strategy Lead
$104K - $143K *
Unlock your potential by leading strategic initiatives that drive measurable business results. Collaborate with senior leaders to solve complex problems, evaluate opportunities, and translate strategy...
3 weeks ago
VP OF SALES - WEST COAST - HEALTHCARE
$160K - $200K *
Join a dynamic team as a senior leader driving profitable growth in healthcare services. Oversee sales strategy, lead a high-performing team, and collaborate across functions to deliver innovative sol...
Reposted yesterday
Vice President, Regulatory Strategy Diligence
$285K - $385K *
Lead regulatory due diligence for clinical/commercial assets, assessing risks and strategies for licensing, acquisitions, and partnerships. Collaborate across teams to ensure regulatory integration in...
Today
$150K - $180K *
Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...
3 weeks ago
Manager, Health Informatics (Southeast)
$152K - $253K *
Drive impactful health informatics initiatives across multiple states, enhancing care delivery through strategic partnerships and technology alignment. Collaborate with health systems to optimize work...
6 days ago
Manager, Health Informatics (Southeast)
$152K - $253K *
Join a dynamic team to enhance healthcare delivery through health informatics. Collaborate with health systems and GSK teams to align technology with clinical workflows, improving patient care and ope...
6 days ago
$85K - $100K *
Help us optimize Epic applications by leading projects, troubleshooting issues, and ensuring seamless integration. Collaborate with teams to enhance workflows and provide expert support, all while mai...
1 week ago
Associate Director, Global Value & Access, Hematology
$153K - $203K *
Drive global access and pricing strategies for hematology assets, ensuring timely reimbursement and optimal patient access. Collaborate with cross-functional teams to develop evidence-based toolkits a...
3 weeks ago
Medicare Risk Adjustment Compliance Auditor (CPC, CCS, or CCS-P Required) (Remote)
$64K - $96K *
Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...
Reposted 1 week ago
Epic Application Analyst - ClinDoc/Stork
$80K - $95K *
Unlock potential by managing system design, build, and support for applications, ensuring optimal functionality and user satisfaction while collaborating across teams to enhance workflows and resolve...
1 week ago
Cardiovascular Account Specialist - U.S. Sales, Philadelphia East, PA
$162K - $195K *
Shape the future of cardiovascular care by driving the launch of a novel cardiac myosin inhibitor. Collaborate with healthcare professionals and internal teams to establish strategic relationships and...
2 days ago
Director of Active Ingredient Supply (GCS)
$125K - $150K *
Transform supply chain operations by leading procurement, inventory management, and cash planning. Collaborate with cross-functional teams to ensure product delivery, regulatory compliance, and contin...
Yesterday
$80K *
Empower clients by managing complex care needs through remote case management, ensuring access to high-quality treatment and support. Collaborate with multidisciplinary teams to enhance client engagem...
2 weeks ago
Physical Therapist Home Health
$80K - $95K *
Elevate patient care by developing tailored rehabilitation plans, performing evaluations, and delivering effective treatments. Collaborate with a dedicated team to enhance patient outcomes and ensure...
2 weeks ago
Sr. Director, Regional Sales, Central - Intismeran
$196K - $353K *
Empower your career by leading a dynamic oncology sales team to drive regional strategy and execution. Collaborate with partners to launch innovative therapies, build key relationships, and shape the...
1 week ago
Director, Neurology - Thought Leader Liaison (Central)
$245K - $265K *
Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...
2 weeks ago
$150K - $180K *
Shape the future of AI evaluation by leading rigorous methodologies, collaborating with engineers, and mentoring teams to ensure accurate assessments that drive product innovation and market standards...
3 days ago
Senior Compliance Program Manager, GRC
$120K - $140K *
Drive compliance excellence as a Senior Compliance Program Manager, overseeing complex initiatives across enterprise and federal environments. Collaborate with cross-functional teams to ensure audit r...
2 weeks ago
$120K - $140K *
Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...
2 weeks ago
$72K - $107K *
Join a team that's dedicated to enhancing resident development through effective program management, collaboration with clinical leaders, and innovative professional development sessions to ensure a s...
Today
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.