Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$150K - $160K *

Oversee a team of Regional Facility Managers, developing training programs and implementing maintenance strategies to enhance operational efficiency and cost savings across properties, ensuring a supp...

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$205K - $380K *

Drive transformative supply chain initiatives, providing strategic leadership and operational oversight to enhance efficiency and best practices across client hospitals. Collaborate with C-suite execu...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to managing flood-risk projects and operations in the Susquehanna River Basin. Lead a high-performing team, oversee multi-million-dollar budgets, and collaborate with stak...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$85K - $102K *

Shape the future of flood-risk management by leading multi-million-dollar projects, overseeing operations of critical infrastructure, and guiding a high-performing team to ensure safety and reliabilit...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$85K - $102K *

Join a team that's dedicated to managing flood-risk projects and operations in the Susquehanna River Basin. Lead a high-performing team, oversee multi-million-dollar budgets, and collaborate with stak...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$141K - $186K *

Oversee and manage turnaround events, ensuring effective execution across scoping, budgeting, and communication. Champion safety culture while leveraging technical skills to drive operational excellen...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Business Services

$131K - $176K *

Oversee global Contract Manufacturing partnerships, driving productivity and ensuring quality goals are met. Collaborate cross-functionally to support new product launches and process improvements, wh...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $172K *

Unlock potential by leading product initiatives for 360e Facility Coding, collaborating with diverse teams to enhance customer experiences and drive business value through innovative solutions and eff...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Drive operational excellence in manufacturing by leading teams, optimizing processes, and ensuring safety and quality. Collaborate across functions to meet customer commitments and foster a culture of...

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$106K - $186K *

Elevate your career by leading complex investigations into corporate policy violations. Collaborate with cross-functional teams to assess allegations, gather evidence, and provide actionable recommend...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$106K - $186K *

Unlock your potential by leading complex investigations into corporate misconduct, collaborating with cross-functional teams, and ensuring adherence to compliance standards while driving continuous im...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$208K - $306K *

Join a team that's redefining engineering excellence by leading platform services that enhance software development. Drive innovation, consolidate capabilities, and foster a culture of collaboration t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Transform healthcare branding through innovative art direction. Collaborate with cross-functional teams to create compelling campaigns, guiding projects from concept to execution while mentoring junio...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$183K - $215K *

Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Lead and innovate in sensor technology by developing global engineering teams, driving product development, and shaping the technology roadmap to meet market needs and enhance customer solutions...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$210K - $250K *

Shape the future of mental health and substance use treatment by overseeing clinical care, leading a multidisciplinary team, and ensuring compliance and quality in a dynamic environment focused on hig...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$188K - $245K *

Drive innovative UX design strategies in clinical settings, leading a talented team to enhance decision support and care coordination. Collaborate across functions to integrate AI and elevate user exp...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Lead strategic initiatives in optical networking, shaping business direction and profitability. Collaborate with diverse teams to enhance product offerings and mentor high-performing talent, driving m...

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$120K - $150K *

Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$154K - $208K *

Shape the future of quality operations by leading teams to enhance product excellence and consumer satisfaction across global markets, driving continuous improvement and strategic initiatives in a dyn...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Drive enterprise growth by engaging top health system executives, transforming clinical outcomes through innovative solutions, and building strategic partnerships to expand market presence and adoptio...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$119K - $190K *

Shape the future of our Corporate Functions by partnering with senior leaders to drive talent strategy, organizational effectiveness, and leadership development. Leverage data and insights to influenc...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate business performance by leading financial planning and analysis efforts. Collaborate with cross-functional teams to transform data into actionable insights, driving strategic decision-making a...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.