Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$111K - $145K *

Lead transformative IT projects from inception to completion, ensuring timely delivery and budget adherence. Collaborate across departments to translate business needs into actionable plans while mana...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $135K *

Lead the charge in developing and managing enterprise proposals and plans, ensuring compliance and quality across submissions. Collaborate with cross-functional teams to enhance win strategies and dri...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Accelerate progress at the forefront of strategic initiatives, ensuring alignment with organizational goals. Lead cross-functional teams to deliver measurable outcomes through effective project manage...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Drive the successful lifecycle of engineering projects, ensuring adherence to scope, schedule, and budget while managing customer relationships and internal communications across teams for optimal pro...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$155K - $205K *

Champion process excellence by optimizing workflows and driving cross-functional improvements. Collaborate with teams to enhance operational efficiency, reduce costs, and elevate service quality throu...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$117K - $158K *

Unlock potential by leading complex client engagements, ensuring timely delivery, budget management, and effective resource utilization while navigating challenges in a dynamic environment. Empower te...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Optimize your career as a Technical Project Manager, overseeing equipment procurement and supply chains. Collaborate with cross-functional teams, manage budgets, and negotiate contracts to ensure proj...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Champion integrated project management for complex pharmaceutical advertising, leading cross-functional teams to ensure timely delivery within scope and budget while mentoring junior staff and enhanci...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $148K *

Elevate your career by leading complex R&D projects in orthopaedics. Drive cross-functional teams from concept to launch, ensuring compliance and innovation in medical device development. Your experti...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $148K *

Drive complex R&D projects from initiation to launch, leading cross-functional teams to ensure successful product development in the orthopedic medical device sector. Utilize strong leadership and com...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $182K *

Join a team that's dedicated to transforming business needs into innovative software solutions. Collaborate with clients and developers to ensure high satisfaction and successful adoption while advanc...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $258K *

Elevate enterprise change management by leading a dynamic team to drive communication, readiness, and adoption strategies for a transformative global initiative, ensuring stakeholder engagement and su...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive impactful projects within Geriatrics by managing data, collaborating with teams, and presenting insights to enhance operational efficiency and support strategic goals across the organization...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Drive progress at the forefront of SAP S/4HANA enhancements, managing complex projects and coordinating cross-functional teams to optimize enterprise solutions and deliver measurable business value wh...

Today

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Lead the charge in managing complex ERP implementation projects, ensuring alignment between customer needs and internal resources. Drive project success through effective communication, risk managemen...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the ETF Clearing business, driving strategy, product innovation, and client engagement while ensuring operational excellence and risk management. Collaborate across teams to enhance service deliv...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Join a dynamic team as a Finance Project Manager to drive financial performance and governance across complex rail projects, aligning financial and operational objectives while mentoring teams and opt...

1 month ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $115K *

Oversee all phases of electronic security integration projects, ensuring successful execution from planning to closure. Manage scope, schedule, budget, and quality while collaborating with global clie...

Today

  •   Less than 5 years exp.  •   Staffing

$100K - $115K *

Empower project success by managing real estate initiatives from inception to completion. Collaborate with clients to define project scope, resources, and timelines while ensuring quality and risk man...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $110K *

Lead the charge in managing multiple deployment projects, ensuring customer satisfaction and timely delivery. Collaborate with teams to define goals, mitigate risks, and leverage Fortra products for o...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Join a dynamic team to lead program management initiatives, ensuring alignment with strategic goals. Oversee budgets, guide cross-functional teams, and enhance organizational performance through effec...

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$150K - $258K *

Lead a dynamic team to drive enterprise-wide transformation, integrating complex project management with strategic execution. Oversee the development of an AI-enabled contracting capability, ensuring...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Advance your career by leading large-scale transmission and substation projects. Coordinate cross-functional teams from concept to development stage, ensuring successful project handoff, financial man...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $90K *

Champion project success by managing timelines, resources, and stakeholder communication. Drive seamless implementation experiences while collaborating with cross-functional teams to deliver value-dri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$157K - $283K *

Take ownership of the design and management of high-profile ADA upgrade projects, ensuring effective execution, budget adherence, and client satisfaction while leading cross-functional teams in a dyna...

RemoteRemote

4 weeks ago

  •   15+ years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.