Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$65K - $94K *

Unlock your potential by leading strategic projects that enhance operational effectiveness and drive organizational performance across diverse teams. Collaborate with stakeholders to implement innovat...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$65K - $94K *

Drive operational excellence by managing strategic projects that enhance processes, service delivery, and organizational performance across the College. Collaborate with leadership and stakeholders to...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $175K *

Join a team that's driving transformation in insurance technology by leading complex SaaS programs. You'll ensure delivery excellence, manage risks, and enhance client confidence while shaping the fut...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $159K *

Pioneer the management of clinical research projects, ensuring timely execution and compliance. Collaborate with cross-functional teams to achieve project goals while maintaining strong relationships...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Contribute to impactful projects by evaluating business processes, analyzing data, and implementing solutions. Collaborate with cross-functional teams to ensure project success and drive continuous im...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Drive successful Oracle project implementations by managing cross-functional teams, ensuring timely delivery within budget, and fostering collaboration in an Agile environment. Utilize strong problem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Lead large-scale automation projects, guiding teams through all phases with a focus on customer satisfaction, operational excellence, and financial management in a collaborative environment...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$260K - $280K *

Lead the charge in managing complex SAP S/4HANA projects, coordinating multiple workstreams, and ensuring alignment with strategic priorities while fostering stakeholder collaboration and effective pr...

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $185K *

Collaborate with cross-functional teams to drive product strategy, manage roadmaps, and enhance customer experiences. Lead product initiatives, ensuring alignment with business goals while mentoring j...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $120K *

Transform our proposal development process by crafting compelling narratives and presentations. Collaborate with cross-functional teams to enhance storytelling and optimize resources, ensuring our cap...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $185K *

Unlock your potential by leading a dynamic team to drive channel partnerships, transforming opportunities into revenue-generating relationships across diverse verticals in a fast-growing ecosystem...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead project controls initiatives for large-scale life sciences projects, ensuring effective cost management, scheduling, and reporting. Collaborate with stakeholders to drive performance and deliver...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Drive the successful execution of aerospace engineering programs by leading cross-functional teams, defining project scopes, and implementing strategic plans to meet business goals and customer needs...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in driving strategic growth by managing a high-performing sales team, refining sales strategies, and fostering a culture of excellence to achieve ambitious revenue goals...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by leading complex projects from planning to execution. Collaborate with diverse teams, manage resources, and ensure compliance with safety standards while delivering results on ti...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Transform project execution by leading contractor teams, ensuring quality and adherence to ISO 9001 standards while managing risks and fostering innovation for successful outcomes...

Yesterday

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Empower strategic initiatives by managing cross-functional projects, ensuring accountability, and driving measurable outcomes. Collaborate with stakeholders to integrate dependencies and risks, facili...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $158K *

Transform the Property Intelligence platform by connecting customer needs with product insights. Collaborate across teams to enhance product adoption and engagement through analytics and feedback, dri...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$115K - $172K *

Shape the future of healthcare by leading complex data ingestion initiatives. Collaborate with cross-functional teams to drive program delivery, manage risks, and ensure operational excellence while t...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Champion project success by overseeing complex IT initiatives, coordinating teams, managing budgets, and ensuring seamless integration of systems to enhance operational efficiency and support healthca...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$111K - $150K *

Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$113K - $188K *

Champion the development of innovative tools for customer service teams, enhancing agent efficiency and service quality. Collaborate across departments to drive product strategy, leveraging data and u...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $255K *

Shape the future of digital commerce by driving strategic growth initiatives that enhance customer engagement and purchasing experiences across multiple channels. Lead product strategy and execution t...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to managing study activities in compliance with regulatory standards. Oversee a dynamic group of scientists, ensuring efficient operations and high-quality study support i...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.