Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$110K - $130K *
Join a team that's redefining business identity solutions. As a Product Manager, you'll drive strategy, development, and performance of our Business Identity Graph, collaborating with cross-functional...
3 weeks ago
$110K - $130K *
Unlock potential by directing product strategy for data-centric solutions, collaborating across teams to enhance product performance and drive innovation. Own the product lifecycle from conception to...
3 weeks ago
$95K - $115K *
Elevate product management by integrating diverse datasets into innovative solutions. Collaborate with cross-functional teams to enhance existing products and drive new data initiatives from concept t...
3 weeks ago
$150K - $200K *
Lead the strategy and delivery of complex, high-impact products, collaborating with cross-functional teams to align investments with business objectives. Drive customer-centric innovation while mentor...
4 weeks ago
Subcontractor Risk & SDI Manager
$100K - $150K *
Optimize subcontractor risk management by overseeing prequalification, analyzing financial statements, and enhancing the SDI program. Collaborate with operations to ensure compliance and support proje...
2 weeks ago
$110K - $130K *
Drive innovative solutions by leveraging data analytics and strategic counsel to enhance client performance. Collaborate with high-performing teams to deliver tailored insights for transformational ev...
2 weeks ago
Cultural Resources/Architectural Historian and Senior Project Manager
$135K - $155K *
Join a team that's shaping the future of cultural resources management. As a Senior Project Manager, you'll lead initiatives, mentor staff, and collaborate with experts to enhance our services across...
4 days ago
$210K *
Lead the charge in managing IT projects for our enterprise payments ecosystem. Collaborate with technical teams to develop detailed project plans, ensuring successful execution and alignment with busi...
2 weeks ago
$134K - $249K *
Champion strategic vendor partnerships and enterprise initiatives, overseeing evaluations, negotiations, and performance metrics to drive clinical, operational, and financial success across multiple t...
4 days ago
$130K - $150K *
Join a team that's shaping high-impact strategies and narratives for enterprise growth. Collaborate with senior leaders to craft compelling pitches and support organic initiatives, driving success acr...
Reposted 3 weeks ago
Director, Practice Management Measurement, Reporting & Analysis
$135K - $160K *
Unlock potential by leading analytics and performance management initiatives that drive strategic business outcomes. Transform data into actionable insights, ensuring effective governance and alignmen...
5 days ago
$125K - $155K *
Innovate product strategy and execution, bridging cross-functional teams to deliver impactful solutions that align with customer needs and organizational goals throughout the product lifecycle...
3 weeks ago
Delivery Manager - Decypher Corporate
$135K - $150K *
Unlock potential by overseeing project operations and client relationships, driving growth through strategic partnerships and best practices. Lead teams to achieve business goals while ensuring high s...
2 weeks ago
$92K - $98K *
Take ownership of federal proposal efforts, coordinating cross-functional teams to develop compliant, compelling proposals that align with strategic growth objectives and enhance organizational effect...
2 weeks ago
IT Senior Manager - Portfolio Management Office (PMO)
$120K - $145K *
Lead the charge in transforming portfolio management practices, enhancing strategic alignment, and fostering high-performing teams. Collaborate with executives to drive technology investments that del...
2 weeks ago
Director, Business Transitions
$225K - $250K *
Engage with business owners navigating M&A transactions, providing integrated planning and support. Collaborate with deal teams to ensure seamless transitions and optimize after-tax outcomes during cr...
1 week ago
Director, Proactive Defense Operations
$168K - $281K *
Lead the charge in Proactive Defense Operations, transforming threat data into automated defenses. Drive strategy, team performance, and operational excellence while collaborating across functions to...
1 week ago
Senior Manager, Sales Operations
$115K - $120K *
Lead the charge in driving operational excellence and strategic enablement across global Inside Sales teams, enhancing commercial effectiveness and delivering exceptional client value through innovati...
3 weeks ago
$120K - $145K *
Empower the development of innovative banking solutions by driving product strategy, collaborating across teams, and delivering scalable capabilities that enhance customer experiences and meet busines...
Reposted yesterday
Director, Digital Systems & Strategic Growth
$140K - $180K *
Transform the digital manufacturing landscape by driving sales growth and market expansion. Collaborate across teams to develop strategies, support federal opportunities, and enhance customer value th...
3 weeks ago
Director, Client Media Solutions
$100K - $140K *
Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...
2 weeks ago
Director, Professional Services (Ellucian Colleague and Anthology)
$125K - $150K *
Unlock potential by leading client engagements in higher education, ensuring delivery excellence and fostering executive relationships. Drive project success through oversight, escalation management...
Yesterday
Senior IT Project Manager (NSGS)
$140K - $180K *
Lead the execution of complex IT infrastructure projects, ensuring mission success for critical U.S. Coast Guard programs. Collaborate with stakeholders and manage resources to deliver seamless techno...
1 week ago
$85K - $124K *
Drive impactful SAP projects as a Project Manager/Scrum Master, leading teams to deliver innovative solutions. Collaborate with stakeholders, manage product backlogs, and ensure agile practices to mee...
1 week ago
Senior Manager, Program Management Operations
$143K - $179K *
Lead cross-functional initiatives, optimizing governance and operational readiness for programs. Collaborate with stakeholders to enhance portfolio execution, reporting, and PMO capabilities, driving...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.