Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$85K - $100K *

Join us to empower senior leaders by managing complex projects, client contracts, and travel arrangements. Your proactive support will enhance team efficiency in a fully virtual environment, fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$160K - $236K *

Analyze and drive commercial analytics strategy, establishing strong insights that empower senior leadership's strategic decisions and enhance business performance across a complex, multi-functional e...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$140K - $155K *

Engage with strategic enterprise clients to drive retention, growth, and satisfaction. Lead account strategy, advise stakeholders, and deliver measurable outcomes while mentoring team members and fost...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$135K - $175K *

Shape the future of product data governance and lifecycle management by leading cross-functional teams, ensuring data integrity, and driving compliance across product development and manufacturing pro...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$131K - $176K *

Shape the future of sales excellence by owning end-to-end seller experiences. You’ll optimize workflows, create impactful solutions, and directly influence our revenue systems through innovative produ...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Champion the timely and budget-conscious completion of telecommunications construction projects by leading and mentoring a team of managers, optimizing processes, and ensuring peak productivity across...

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in optimizing marketing operations to drive developer adoption, pipeline growth, and revenue. Oversee systems, processes, and insights while collaborating with cross-functional teams t...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$274K - $457K *

Shape the future of clinical development by leading cross-functional teams, guiding global projects, and driving innovative strategies for regulatory submissions and drug approval in Internal Medicine...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $215K *

Join a dedicated team to shape enterprise strategies in business continuity and risk management while driving operational resilience across the organization. Leverage your expertise to influence decis...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Grow your career with a hands-on marketing leadership role that drives lead generation through strategic content, vendor management, and budget oversight. Collaborate closely with sales to translate i...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $175K *

Join a team that's leading global clinical trials across diverse therapeutic areas. Drive project execution, mentor teams, and ensure milestones are met while collaborating with stakeholders to achiev...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $150K *

Champion the strategic leadership of warehouse labor management and DC excellence, driving operational consistency and continuous improvement across the distribution network while collaborating with c...

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$215K - $235K *

Pioneer comprehensive commercial operations by designing, implementing, and optimizing pricing and deal negotiation processes. Drive ongoing analytics and continuous improvement, ensuring success in a...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Lead project coordination efforts by ensuring effective communication and management of materials, schedules, and documentation. Collaborate with teams to streamline processes and enhance project effi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $100K *

Unlock operational excellence by leading training and change initiatives in data center operations. Collaborate with teams to enhance productivity, quality, and safety while driving continuous improve...

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$171K - $256K *

Drive innovation by leading complex software development programs in cardiac solutions. Collaborate with cross-functional teams to ensure successful execution and delivery, enhancing patient care thro...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $200K *

Champion large-scale, complex data center projects from preconstruction to closeout, ensuring budget, schedule, quality, and safety while navigating fast-paced environments and collaborating with dive...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $219K *

Empower organizational growth by partnering with senior leaders to shape HR strategies that enhance talent management, drive transformation, and foster a high-performance culture within a complex, glo...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$60K - $101K *

Join a dynamic team to oversee ETF and Mutual Fund project management, driving product launches and cross-functional coordination while ensuring effective risk management and operational excellence...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Oversee project resources and documentation throughout the lifecycle, ensuring budget adherence, schedule management, and compliance with contractual obligations while fostering collaboration among st...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $215K *

Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$212K - $333K *

Champion operational excellence in Clinical Data Management, leading strategic initiatives and fostering partnerships to ensure timely, high-quality data delivery for clinical trials. Drive innovation...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$275K - $413K *

Drive high-impact client engagements as a trusted advisor in finance transformation, leading FP&A initiatives while fostering collaboration across diverse industries to enhance decision-making capabil...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$105K - $176K *

Lead the charge in tax compliance and provision management, overseeing federal, state, and local returns. Collaborate cross-functionally to ensure timely filings and support tax strategies for busines...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Lead the charge in transforming partner data operations and integrations, ensuring efficient case resolution and proactive partner enablement. Drive automation, establish standards, and foster a produ...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.