Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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$72K - $90K *

Champion large-scale environmental projects, ensuring safety and compliance while managing complex operations in hazardous waste cleanup and emergency response. Collaborate with teams to deliver effec...

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$175K - $225K *

Contribute to the growth of our retail segment by leading human capital strategies that optimize talent acquisition, performance management, and organizational design in alignment with business object...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$113K - $197K *

Lead the charge in defining product strategy and roadmap, translating business objectives into actionable plans. Collaborate with cross-functional teams to ensure successful implementation and operati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$229K - $267K *

Innovate the consumer digital experience by leading a cross-functional team to enhance our website, mobile app, and web portal. Define a multi-year vision, prioritize initiatives, and drive engagement...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $150K *

Drive HRIS excellence by optimizing technologies and core processes, enhancing compliance, and delivering impactful solutions that elevate operational efficiency and employee experience across the org...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$155K - $170K *

Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Staffing

$130K - $160K *

Lead the charge in driving excellence in R&D Quality Change Management, ensuring compliance and standardization across functions while mentoring a global network of experts to foster collaboration and...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $147K *

Lead the charge in operational excellence by managing a dynamic Facility Services team, enhancing customer experience, and driving business growth through effective service delivery and continuous imp...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $170K *

Lead a dedicated team to drive client success across diverse delivery modes, ensuring effective governance and coordination. Drive business development within a portfolio, nurturing critical client re...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$99K - $232K *

Shape client success by leading capital markets accounting advisory projects, managing teams, and delivering strategic insights during transformational events. Drive project execution and ensure align...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$138K - $150K *

Drive your career forward by managing corporate portfolio growth through strategic projects and business development in digital health and emerging technologies, collaborating with leadership and cros...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$82K - $92K *

Unlock potential by managing SaaS implementation projects for public-sector clients. Collaborate with stakeholders to ensure timely delivery of grants management solutions while enhancing project meth...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $140K *

Partner with us to lead PaaS delivery initiatives, ensuring effective operations, solid stakeholder management, and strategic oversight for veteran services. Drive project lifecycles, enhance delivery...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$262K - $419K *

Empower teams to deliver mega transit projects by leading design efforts, managing client relationships, and ensuring project success through collaboration and strategic planning. Drive performance ob...

2 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$149K - $171K *

Take ownership of the developer engagement platform, enhancing diagnostic tools and automated workflows. Drive seamless user experiences and governance automation to empower teams in addressing test f...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$138K - $150K *

Drive strategic growth by managing corporate portfolio and M&A initiatives. Collaborate with cross-functional teams to identify opportunities, conduct analyses, and execute projects that enhance busin...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $150K *

Champion strategic growth by managing corporate portfolio and M&A initiatives. Collaborate with cross-functional teams to identify opportunities, conduct due diligence, and drive new business developm...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $150K *

Lead strategic initiatives to enhance corporate portfolio growth through M&A and new business development, focusing on digital health and emerging technologies while collaborating with cross-functiona...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $150K *

Elevate your career by managing corporate portfolio growth through strategic projects and business development in digital health and emerging technologies. Collaborate with leadership and cross-functi...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $150K *

Partner with us to drive corporate portfolio growth through strategic M&A and business development initiatives. Collaborate with cross-functional teams to identify opportunities in digital health and...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $150K *

Analyze and manage corporate portfolio growth through strategic projects and business development. Collaborate with cross-functional teams to drive M&A initiatives and evaluate market opportunities, e...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the evolution of our GTM Systems Architecture, enhancing Salesforce and its tech stack for AI-native workflows. Collaborate with cross-functional teams to build a trusted data foundation and driv...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$185K - $256K *

Elevate the market growth strategy for biologics research, driving software adoption and AI use cases. Collaborate with global teams and engage with industry leaders to shape the future of molecular t...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Drive operational excellence by enhancing efficiency, managing costs, and implementing strategic tools. Collaborate with cross-functional teams to optimize performance and support business growth thro...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.