Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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Director, Program Management Jobs in North Carolina

Sort By: Relevance

$140K - $170K *

Shape the success of enterprise health systems by leading full implementations. Collaborate cross-functionally to manage project lifecycles, mitigate risks, and ensure smooth transitions to customer s...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $155K *

Lead the successful execution of projects by managing teams, fostering collaboration, and ensuring adherence to methodologies. Drive talent development and build strong relationships across functions...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$124K - $155K *

Oversee project management operations, ensuring adherence to methodologies while fostering team development and collaboration. Drive successful project outcomes through strong leadership and relations...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$131K - $190K *

Lead strategic initiatives that enhance customer engagement and drive actionable insights. Collaborate cross-functionally to improve processes, connect feedback to decisions, and advance customer expe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $214K *

Join a team that's redefining healthcare product management through innovative supply chain solutions. Lead cross-functional initiatives and shape the future of resilience in healthcare with strategic...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$92K - $154K *

Lead the charge in managing complex IT projects from initiation to delivery, ensuring alignment with business objectives and stakeholder needs while driving process improvements and risk mitigation st...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$209K - $239K *

Drive complex technical initiatives and lead multi-year integration strategies to enhance platform capabilities, ensuring alignment with business objectives and fostering a culture of excellence in Te...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in shaping global healthcare packaging design. As a Principal Design Program Manager, you'll establish frameworks and standards, drive strategic decisions, and ensure seamless collabor...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$137K - $172K *

Shape the future of technology delivery by leading complex, cross-functional programs that drive business value. Oversee strategic initiatives, ensuring excellence in execution, client satisfaction, a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$114K - $143K *

Drive operational excellence as a Program Manager, enhancing EPD processes and collaboration. Leverage data insights to identify trends, improve efficiency, and support cross-functional teams in a dyn...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Lead cross-functional efforts to drive execution in a fast-paced remote environment, overseeing key product initiatives and customer issues in our Privileged Access Management portfolio, while ensurin...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $100K *

Elevate your career by leading cross-functional projects, ensuring timely deliverables and driving process improvements through collaboration and expert project management methodologies...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $150K *

Lead product management for complex digital services, mentoring a team of Product Managers. Collaborate with stakeholders to define strategies, prioritize needs, and deliver impactful outcomes while f...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$161K - $202K *

Analyze business operations to drive strategic improvements in health coaching. Collaborate with cross-functional teams to enhance program outcomes, utilizing data-driven insights and effective commun...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$138K - $165K *

Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $200K *

Lead the charge in delivering complex federal digital services programs, ensuring strategic direction, operational excellence, and strong customer relationships across multidisciplinary teams while ma...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Empower our project management team by leading complex engineering programs, enhancing processes, and fostering client relationships. Drive successful project delivery while mentoring staff and shapin...

1 week ago

  •   11 - 15 years exp.  •   Technical Services

$107K - $150K *

Shape the future of our enterprise data platform by leading product strategy, defining capabilities, and ensuring alignment across business and technology teams to deliver scalable, secure, and truste...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $108K *

Champion high-impact strategic initiatives, collaborating with executives to drive alignment and measurable results across the organization while navigating complexity and change...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Unlock potential by leading product vision and strategy, driving customer insights to align with business goals. Collaborate across teams to deliver innovative solutions, ensuring impactful outcomes f...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $265K *

Lead enterprise data strategy by defining governance frameworks and driving data-driven decision-making. Collaborate with cross-functional teams to enhance data capabilities, ensuring compliance and o...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Manage cross-functional projects from concept to commercialization, ensuring timely delivery and effective communication among teams. Mentor new members and navigate project challenges while maintaini...

Reposted yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$88K - $105K *

Lead the charge in managing cross-functional product-related projects, guiding teams through formulation and commercialization phases. Collaborate effectively to meet timelines, drive project success...

Reposted yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$126K - $202K *

Lead impactful initiatives by analyzing data and building tools that drive revenue growth. Collaborate with product teams to identify gaps, streamline processes, and enhance enterprise readiness, ensu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Drive your career forward by leading complex healthcare onboarding projects. Manage multiple workstreams and stakeholders to ensure successful implementation and customer satisfaction while navigating...

3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.