Director, Clinical Science Jobs

Explore Director, Clinical Science opportunities on Ladders, where experienced professionals can find vetted jobs paying $100,000 or more. Directors in clinical science help shape the development of new therapies by guiding clinical research strategy, interpreting evidence, and leading teams through complex studies.

What Does a Director of Clinical Science Do?

Directors of Clinical Science provide scientific leadership across clinical development programs. They may contribute to study design and protocols, assess clinical data, support regulatory submissions, and work with medical, statistical, regulatory, and operational teams to advance trials. Responsibilities vary by employer, therapeutic area, and stage of development.

Skills and Qualifications

Employers commonly seek substantial clinical research or drug-development experience, strong scientific judgment, and the ability to communicate complex findings clearly. Leadership, cross-functional collaboration, familiarity with clinical trial processes, and experience interpreting clinical data are valuable. Requirements may include an advanced degree in a relevant scientific or medical field, depending on the position.

Career Opportunities

Director-level clinical science roles can be found at biotechnology and pharmaceutical companies, clinical research organizations, and other healthcare organizations. Opportunities may focus on a specific therapeutic area, clinical program, or phase of development. Review each listing for details about scope, qualifications, location, and compensation.

Find Director, Clinical Science Jobs on Ladders

Browse vetted Director, Clinical Science job listings on Ladders and discover opportunities with salaries of $100,000 or more. Use job details to compare roles and identify positions that align with your experience and career goals.

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$245K - $332K *

Join us to lead the PV Science department, driving strategic safety management and aggregate reporting for all products. Collaborate with cross-functional teams to enhance risk management processes an...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$245K - $332K *

Drive strategic leadership in pharmacovigilance, managing teams to enhance safety profiles and aggregate reporting for all product lifecycles. Collaborate cross-functionally to implement risk manageme...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $205K *

Shape the future of clinical operations by leading strategic initiatives, optimizing workflows, and driving cross-functional projects. Collaborate with senior leaders to enhance efficiency and ensure...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $205K *

Lead the charge in optimizing clinical operations and strategy, driving cross-functional projects from ideation to implementation. Collaborate with senior leaders to enhance workflows, ensure complian...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$217K - $264K *

Drive your career with a leadership role in translational medicine, overseeing biomarker strategies for neurological drug development. Collaborate with cross-functional teams to deliver impactful solu...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$244K - $295K *

Champion innovative translational strategies for neurological drug development, leading biomarker activities and collaborating with cross-functional teams to enhance clinical trial outcomes and delive...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$244K - $295K *

Shape the future of neurological research by leading translational medicine initiatives. Drive biomarker strategies, collaborate with cross-functional teams, and ensure timely data delivery to support...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$240K - $291K *

Unlock potential by leading translational medicine initiatives for neurological and neuropsychiatric drug development, collaborating with cross-functional teams to drive biomarker strategies and ensur...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$240K - $328K *

Unlock potential by leading HEOR strategies to demonstrate the healthcare value of products. Collaborate with cross-functional teams to create evidence for informed decision-making, while managing pro...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$261K - $346K *

Lead the charge in clinical pharmacology strategies for rare disease and oncology programs, driving innovative solutions, study designs, and regulatory interactions to expedite drug development and im...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$201K - $360K *

Lead safety initiatives by shaping the future of pharmacovigilance, driving oversight, managing risks, and collaborating across teams to enhance product safety throughout the lifecycle, fostering inno...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $275K *

Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$220K - $250K *

Drive drug safety and pharmacovigilance strategy in a dynamic biotech environment, overseeing key regulatory interactions and safety assessments across multiple development programs. Lead the establis...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$254K - $308K *

Shape the future of Global Medical Psychiatry by leading innovative strategies for Schizophrenia. Oversee medical activities, foster key partnerships, and drive the execution of groundbreaking project...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$89K - $123K *

Innovate operational delivery for early-phase clinical studies by managing vendor collaborations, ensuring compliance, and integrating protocols. Drive project management to deliver high-quality resul...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $200K *

Transform the Safety Assessment department by leading GLP compliance, developing strategic plans, and ensuring operational excellence while mentoring staff and engaging with clients to meet their need...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead global clinical operations to ensure timely delivery of complex clinical studies, fostering collaboration, and driving patient engagement while managing budgets and compliance effectively...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead dynamic medical writing initiatives while enhancing quality control processes and managing client relationships. Collaborate cross-functionally to drive improvements, oversee resource management...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$213K - $243K *

Champion the development of a robust commercial data strategy, ensuring high-quality, AI-ready data solutions that drive impactful decision-making and enhance commercial performance across the organiz...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K - $163K *

Empower clinical development through scientific leadership in biomarker and bioanalytical strategies, guiding assay design, CRO oversight, and regulatory submissions in a fast-paced environment...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$240K - $328K *

Shape the future of medical affairs by developing strategic plans, driving data generation, and fostering key relationships. Collaborate across functions to enhance understanding and communication of...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the establishment and operations of a new clinical research site, ensuring participant safety and data integrity while driving financial and enrollment goals. Collaborate with teams to foster a c...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Lead evidence generation and scientific communications to support innovative gene therapy initiatives. Collaborate with cross-functional teams to identify evidence gaps and execute strategic plans, en...

New York, NYRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Lead the charge in evidence generation and scientific communications, driving strategic initiatives to support gene therapy programs. Collaborate with cross-functional teams to identify evidence gaps...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$181K - $225K *

Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Science do?question toggle

    A Director of Clinical Science provides scientific leadership for clinical development programs, helping guide study design, evaluate clinical evidence, and collaborate with cross-functional teams. Specific duties depend on the organization and therapeutic area.

  • What qualifications are typically required for Director, Clinical Science jobs?question toggle

    Requirements vary, but employers often look for extensive clinical research or drug-development experience, scientific expertise, leadership skills, and the ability to interpret and communicate clinical data. Some roles require an advanced degree in a relevant field.

  • Where do Directors of Clinical Science work?question toggle

    They may work for pharmaceutical and biotechnology companies, clinical research organizations, and other healthcare or life sciences organizations.

  • What salary range can I find for these jobs on Ladders?question toggle

    Ladders features vetted professional jobs paying $100,000 or more. Check individual listings for the specific compensation range and benefits.

  • How can I find the right Director, Clinical Science role?question toggle

    Compare listings by therapeutic area, responsibilities, required experience, location, and compensation. Focus on roles that match your clinical development background and leadership goals.