Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$76K - $148K *

Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in delivering quality clinical services through strategic oversight, efficient operations, and continuous improvement, ensuring compliance and optimal patient care in a home care setti...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Lead the charge in enhancing clinical services by effectively overseeing operations, ensuring compliance, and driving quality patient care initiatives to support the mission of delivering hope and hea...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $331K *

Join a dynamic team to provide strategic Clinical Science leadership across multiple vaccine studies and programs. Leverage your expertise to shape development strategies, ensure scientific consistenc...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $331K *

Join a team that's shaping the future of vaccine development by providing strategic Clinical Science leadership across multiple studies and programs, ensuring scientific consistency and collaboration...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $331K *

Join a team that's shaping the future of vaccine development by providing strategic Clinical Science leadership across multiple studies and programs. Leverage your expertise to drive scientific consis...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage comprehensive clinical data activities, ensuring oversight from study startup through database lock. Lead cross-functional teams, guarantee vendor performance, and uphold data quality standards...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Manage and enhance clinical operations, supporting quality assurance and building strong relationships between hospital staff, PCPs, and patients. Drive performance improvement through data analysis a...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $150K *

Manage clinical operations by leading trial planning, vendor oversight, and budget management. Collaborate with cross-functional teams to ensure compliance and drive process improvements while maintai...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $146K *

Join a team that's dedicated to providing exceptional executive support and managing office operations. Collaborate with senior leaders in a fast-paced environment, ensuring seamless coordination of a...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's committed to delivering exceptional client care while leading operations, sales, and clinical performance in a dynamic environment. Own clinic success through strategic direction, e...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$238K - $323K *

Partner with us to shape the medical strategy for early-stage CNS clinical programs, driving scientific engagement and collaboration across teams to enhance patient access and commercial growth in neu...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $235K *

Lead the charge in enhancing behavioral health services by providing clinical leadership, oversight, and consultation. Collaborate with teams to ensure high-quality care and compliance while driving c...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$192K - $266K *

Drive best-in-class travel support through strategic leadership and operational excellence. Oversee lodging, flights, and customer advocacy, fostering a culture of continuous improvement and exception...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $100K *

Lead the charge in overseeing day habilitation operations, ensuring compliance and high-quality services while fostering professional growth among program staff and promoting a positive work environme...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$315K - $335K *

Transform healthcare delivery by leading clinical practices, enhancing patient care, and driving operational excellence in a dynamic health center environment. Collaborate with teams to achieve health...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Lead the development and management of outpatient services, ensuring compliance and program effectiveness. Collaborate with clinical staff to enhance patient care and operational efficiency while driv...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$230K - $250K *

Pioneer innovative regulatory strategies for global clinical development, leading cross-functional teams and ensuring compliance with health authority requirements. Drive submissions and represent the...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$104K - $130K *

Lead the charge in enhancing care center operations, overseeing staff management, financial performance, and quality patient care while fostering community relationships and driving growth initiatives...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$213K - $286K *

Drive regulatory CMC strategy and execution for biologics programs, ensuring high-quality submissions and compliance with global standards. Collaborate across teams to guide development strategy and i...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Drive strategic business development initiatives to enhance R&D and commercial growth. Collaborate with cross-functional teams to assess opportunities, negotiate deals, and present findings to senior...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $184K *

Transform the Provider Network operations by leading strategic initiatives, enhancing provider relations, and ensuring compliance across multiple lines of business. Drive performance and collaboration...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Accelerate progress at a leading healthcare provider network by overseeing operations, enhancing provider relations, and ensuring compliance across multiple lines of business. Drive strategic initiati...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Join a team that's redefining healthcare provider network operations. Oversee strategic initiatives across multiple divisions, ensuring compliance and operational excellence while enhancing provider r...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Transform the future of healthcare provider networks by leading operational excellence, strategic initiatives, and cross-departmental collaboration to enhance provider relations and data management ac...

Georgia, USRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.