Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$80K - $95K *

Empower a dedicated team to enhance resident health and wellness while ensuring compliance with regulations. Lead daily healthcare operations, develop personalized care plans, and foster a culture of...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Oversee strategic physician leadership for clinical documentation initiatives, driving performance improvement and operational excellence while fostering collaboration across healthcare teams to enhan...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $98K *

Drive best practices in long-term care by providing leadership, mentoring, and support to nursing teams. Oversee medication reconciliation, implement evidence-based programs, and foster a culture of c...

Toronto, ONIn-Person

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Transform healthcare delivery by leading an interdisciplinary team to enhance patient outcomes through a collaborative, outcomes-centered approach across multiple facilities...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Shape operational excellence by leading cross-functional teams, driving strategic initiatives, and fostering a culture of continuous improvement to support growth and efficiency in a dynamic environme...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$92K - $213K *

Shape laboratory operations in a regulated environment, leading teams to ensure compliance, quality, and efficiency. Drive strategy, manage performance, and foster continuous improvement across functi...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$92K - $213K *

Drive laboratory operations in a regulated environment, ensuring compliance and quality. Lead teams, manage performance, and implement continuous improvement strategies to enhance efficiency and opera...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Join us in leading population health initiatives through innovative, team-based care. Collaborate closely with Advanced Practice Clinicians to ensure excellence in patient care and client relations ac...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a dedicated team focused on enhancing population health through innovative, outcomes-centered care. Collaborate with interdisciplinary professionals to ensure high-quality, accountable patient ca...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Join a dedicated team as you lead population health initiatives, ensuring high-quality, team-based care across facilities. Collaborate closely with Advanced Practice Clinicians to enhance patient outc...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Empower population health as a key leader in client facilities, ensuring excellence in patient care and collaboration with Advanced Practice Clinicians. Drive high-quality, accountable, team-based car...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Transform healthcare delivery by leading a dedicated team in providing exceptional patient care. Collaborate closely with Advanced Practice Clinicians to enhance outcomes and ensure excellence in clie...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Shape the future of population health by providing leadership in client facilities, ensuring high-quality, team-based care, and collaborating closely with Advanced Practice Clinicians to enhance patie...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Empower patient care by leading interdisciplinary teams in a collaborative environment. Drive excellence in population health through innovative practices and ensure high-quality, accountable care acr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in enhancing population health through collaborative, team-based care. Drive excellence in patient outcomes and client relations while overseeing clinical leadership in multiple facili...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a dedicated team focused on enhancing population health through innovative, team-based care. Collaborate closely with Advanced Practice Clinicians to ensure excellence in patient care and client...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in population health by delivering high-quality, team-based care. Collaborate with Advanced Practice Clinicians to enhance patient outcomes and ensure excellence in client relations ac...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Join a team that's dedicated to enhancing population health through innovative care models. Collaborate with advanced practitioners to deliver high-quality, accountable healthcare across facilities wh...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in population health by delivering high-quality, team-based care. Collaborate with Advanced Practice Clinicians to enhance patient outcomes and professional relationships while meeting...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Support population health initiatives by providing leadership and high-quality, team-based patient care. Collaborate closely with Advanced Practice Clinicians and facility leadership to ensure excelle...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Shape the future of population health by delivering excellence in patient care through collaborative leadership with Advanced Practice Clinicians in a dynamic healthcare environment...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Lead the charge in advancing population health through collaborative care, ensuring excellence in clinical practices and team dynamics within diverse healthcare environments...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Deliver high-quality, team-based healthcare while collaborating closely with clinicians to enhance patient outcomes in a meaningful way, ensuring excellence in care across assigned facilities and lead...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Provide leadership in population health management, ensuring excellence in team-based patient care across multiple facilities while collaborating closely with Advanced Practice Clinicians for optimal...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Partner with us to elevate patient care by leading a dedicated team in a rewarding healthcare environment that focuses on population health and team-based approaches for improved quality outcomes and...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.