Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Associate Director, Patient Safety & Pharmacovigilance Compliance, Standards & Training
$183K - $242K *
Lead critical PSPV compliance initiatives, ensuring adherence to regulations while guiding cross-functional teams through risk-based recommendations and quality improvements for safety standards withi...
Reposted 4 weeks ago
$91K - $104K *
Lead the development and implementation of innovative therapy programs, ensuring high-quality patient care and compliance with standards in a dynamic senior living environment. Supervise a team of the...
Today
Center Operations Director - Fallsgrove
$80K - $100K *
Transform operations and lead a high-performing team to ensure exceptional family experiences while driving center performance and growth through strong leadership and problem-solving...
Reposted 4 days ago
Associate Clinical Supply Chain Director
$161K - $228K *
Transform clinical supply strategies by managing forecasting, packaging, and distribution for trials. Collaborate with cross-functional teams to ensure timely drug supply and compliance with regulatio...
1 week ago
Senior Manager, Arbitration Operations
$100K - $120K *
Empower operational excellence by leading arbitration processes, enhancing workflows, and developing a high-performing team. Drive accountability and quality control while ensuring timely client onboa...
2 weeks ago
Sr. Manager, Account Management & Operations
$102K - $171K *
Lead and optimize customer support operations, driving exceptional experiences and fostering a culture of service excellence. Collaborate with stakeholders to resolve challenges and enhance operationa...
4 days ago
Sr. Manager, Account Management & Operations
$102K - $171K *
Empower customer success by leading and transforming support operations. Drive strategic initiatives, enhance team performance, and foster collaboration across departments to deliver exceptional exper...
4 days ago
Sr. Manager, Account Management & Operations
$102K - $171K *
Lead the charge in optimizing customer support operations, driving exceptional experiences and strategic initiatives while managing a team. Foster collaboration and continuous improvement to enhance s...
4 days ago
Clinical Program Director, Early CVRM Clinical Development
$233K - $350K *
Drive the strategic direction and execution of clinical programs, ensuring timely, cost-effective delivery. Collaborate with cross-functional teams to enhance drug development efforts and promote qual...
3 weeks ago
Senior Recruiting Manager, Clinical Pharmacy and Behavioral - Hybrid
$129K - $215K *
Lead the charge in building clinical teams to enhance access and quality care. Drive talent strategies in partnership with senior leaders, ensuring alignment with business growth and workforce readine...
Yesterday
Senior Recruiting Manager, Clinical Pharmacy and Behavioral - Hybrid
$129K - $215K *
Accelerate progress at building clinical teams that enhance access and quality care. Lead a recruiting team to align talent strategies with business goals across Pharmacy and Behavioral Health, ensuri...
Yesterday
Senior Recruiting Manager, Clinical Pharmacy and Behavioral - Hybrid
$129K - $215K *
Empower clinical excellence by leading a dynamic recruiting team to develop innovative talent strategies that enhance workforce readiness and support growth across Pharmacy and Behavioral Health secto...
Yesterday
$180K - $220K *
Unlock potential by leading clinical services as a Medical Director, ensuring quality healthcare delivery in a correctional setting. Collaborate with staff and community providers to enhance patient c...
1 week ago
Nursing Director of Operations-Maternity and Nursing Support Services
$110K - $130K *
Join us in leading operational excellence across departments, driving strategic goals, and enhancing clinical practices. You'll manage teams, implement innovative solutions, and ensure compliance whil...
Yesterday
Clinical Director-Licensed Physical Therapist
$95K - $110K *
Lead a dedicated team in delivering exceptional patient care while managing clinic operations, growth, and community relationships. Empower your career in a supportive environment focused on mentorshi...
1 week ago
Director, Production Operations
$110K - $130K *
Champion operational excellence by leading production processes, ensuring compliance, and driving strategic initiatives. Collaborate cross-functionally to enhance performance, develop future leaders...
2 weeks ago
$215K - $408K *
Transform healthcare delivery by leading medical management and quality initiatives. Collaborate with clinical teams to enhance patient outcomes and drive cost-effective care while ensuring compliance...
Today
$90K - $110K *
Lead and inspire multidisciplinary clinical teams to enhance patient care, ensure regulatory compliance, and implement evidence-based treatment programs. Drive quality outcomes and foster a culture of...
3 days ago
$100K - $120K *
Advance your career by leading impactful clinical services, overseeing multidisciplinary teams, and driving evidence-based practices. Shape exceptional patient care and operational success at a renown...
3 weeks ago
$80K - $95K *
Champion high standards of clinical excellence by leading program development, ensuring patient-centered care, and fostering a culture of accountability. Collaborate with teams to optimize outcomes an...
3 weeks ago
$100K - $120K *
Lead and inspire a clinical team delivering exceptional behavioral healthcare. Drive program development, ensure quality patient outcomes, and foster a culture of compassionate care while navigating r...
4 weeks ago
Director, Companion Diagnostic Program Manager
$194K - $291K *
Lead strategic initiatives in developing and executing companion diagnostic assays, ensuring integration into oncology programs while maintaining compliance and quality standards. Collaborate cross-fu...
Reposted 2 weeks ago
Director, Companion Diagnostic Program Manager
$194K - $291K *
Lead the strategic and operational execution of companion diagnostic projects in oncology, ensuring alignment with clinical development and regulatory standards while driving cross-functional collabor...
2 weeks ago
Manager - Clinical - Surgical Services
$80K - $95K *
Transform patient care services by leading a dedicated team, ensuring high-quality outcomes, and fostering collaboration across departments to enhance operational efficiency and patient experience...
Today
Director - Intensive Community Support (ICS) Program
$84K *
Join a team that's dedicated to supporting mental health consumers in transitioning from hospital to community living. Oversee clinical operations, enhance team collaboration, and foster a compassiona...
Reposted 4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.