Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$156K - $215K *

Transform quality engineering practices across a technology portfolio by leading teams to enhance delivery quality, test automation, and continuous improvement, ensuring alignment with enterprise stan...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$109K - $179K *

Join a team that's integral to executing complex clinical trials by managing key imaging operations and collaborating with cross-functional teams to ensure high-quality data acquisition and compliance...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $179K *

Unlock potential by managing imaging operations for clinical trials, coordinating with diverse teams to ensure high-quality data collection and compliance. Drive collaboration with vendors and clinica...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $179K *

Support clinical imaging operations for diverse trials, ensuring high-quality data acquisition and compliance with imaging protocols through collaboration with cross-functional teams and vendor manage...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$154K - $211K *

Drive operational excellence in PRC Marketing by enhancing content approval processes, collaborating with stakeholders, and delivering insights on performance metrics to ensure compliance and efficien...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Lead product safety initiatives for early development products, ensuring effective safety surveillance, risk management, and regulatory compliance while collaborating with cross-functional teams to dr...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$167K - $207K *

Lead the charge in shaping regulatory operations by enhancing submission processes, governance, and systems. Drive high-quality global submissions while fostering collaboration and visibility across t...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $141K *

Lead the charge in enhancing operational effectiveness and strategic growth across multiple outpatient practices, ensuring high-quality patient access and financial performance within a collaborative...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Lead statistical programming initiatives across clinical development programs, ensuring quality and timely deliverables for regulatory submissions and analyses. Collaborate with cross-functional teams...

2 weeks ago

  •   11 - 15 years exp.  •   Staffing

$225K - $250K *

Join a dynamic team focused on enhancing enterprise applications, driving innovation, and ensuring seamless operations across business platforms. Lead cross-functional teams to optimize technology sol...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$225K - $250K *

Shape the future by leading the strategy and enhancement of enterprise applications, ensuring seamless integration and a zero incidents support model. Drive innovation, partner with business leaders...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Optimize healthcare operations by leading clinical and administrative teams to enhance patient care, ensure compliance, and drive efficiency. Utilize clinical expertise and management skills to foster...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$126K - $200K *

Transform the Safety Assessment department by leading GLP compliance, developing strategic plans, and ensuring operational excellence while mentoring staff and engaging with clients to meet their need...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Elevate operational excellence by partnering with leadership to drive strategic initiatives, enhance productivity, and foster a culture of continuous improvement. Lead change management and communicat...

Edmonton, ABIn-Person

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join a team that's dedicated to managing and enhancing clinical programs, ensuring quality patient care through effective leadership and collaboration with multidisciplinary teams to drive positive he...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$196K - $269K *

Champion innovative strategies in incentive compensation and sales planning, driving performance and customer engagement across diverse teams. Collaborate with leadership to optimize field execution a...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$196K - $269K *

Empower commercial success by leading incentive compensation and sales planning strategies. Collaborate with cross-functional teams to optimize field execution, drive performance, and enhance customer...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $110K *

Join a team that's dedicated to enhancing clinical nursing services and ensuring quality care outcomes. This leadership role involves coordinating resident care, managing staff performance, and suppor...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Empower clinical excellence by leading a state-of-the-art chiropractic practice, driving patient care, and cultivating a dynamic team. Bring your entrepreneurial spirit to shape the clinic’s future wh...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Lead the daily operations of a medical group, ensuring productivity and efficiency across various departments. Collaborate with staff and physicians to enhance patient services and implement effective...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$186K - $233K *

Shape the future of clinical supply planning by leading global strategies, ensuring accurate demand forecasting, and driving process improvements for clinical programs. Collaborate with cross-function...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of behavioral health by leading strategic marketing and intake services. Drive growth, mentor teams, and enhance community care through innovative business development initiatives acr...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $170K *

Lead clinical operations for a transformative pretrial supervision program, ensuring adherence to best practices and enhancing service delivery through innovative training and quality assurance initia...

2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$140K - $170K *

Elevate clinical practice within the Supervised Release Program by ensuring adherence to best practices, enhancing service delivery, and fostering innovation in participant care through comprehensive...

2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$164K - $205K *

Elevate clinical operations by leading complex trials, ensuring compliance, and driving cross-functional collaboration. Utilize your expertise to manage timelines, budgets, and stakeholder communicati...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.