Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$117K - $156K *

Shape the future of clinical trials by managing the execution and oversight of Class III medical device studies. Collaborate with teams and ensure compliance, quality standards, and operational succes...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Lead the charge in designing and implementing a scalable home-based care model, ensuring high-quality, patient-centered care through interdisciplinary collaboration and continuous improvement across d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$174K - $205K *

Join us to lead clinical data management for diverse trials, ensuring data integrity and compliance. Collaborate with cross-functional teams to optimize processes and drive excellence in drug developm...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by providing strategic leadership in home health operations, ensuring compliance, driving growth, and enhancing patient outcomes while fostering a high-performing team dedicated to qu...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $213K *

Transform healthcare education by leading innovative omnichannel strategies that enhance medical learning experiences. Collaborate with diverse teams to create impactful content and solutions that mee...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive scientific strategy and lead therapeutic programs in neurobiology, overseeing target validation to preclinical proof-of-concept. Collaborate with teams to identify novel targets and foster partn...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$280K - $305K *

Innovate in musculoskeletal care by designing scalable systems and leading a dedicated team. Transform how patients receive care, integrating advanced technology while ensuring high-quality, empatheti...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $305K *

Join a team that's redefining musculoskeletal (MSK) care by designing innovative, scalable solutions to improve patient outcomes and delivering high-quality, empathetic care to diverse populations wit...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive clinical research operations for a multidisciplinary program focused on inflammatory and autoimmune diseases, ensuring rigorous execution of studies while collaborating with diverse teams to tra...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $225K *

Drive strategic client partnerships, lead a performance-driven team, and manage a portfolio of enterprise accounts to enhance patient access to critical therapies and ensure client satisfaction and gr...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$238K - $341K *

Transform clinical care by guiding a dedicated team of primary care providers to enhance patient outcomes while ensuring high-quality healthcare delivery and operational efficiency at your assigned ce...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform patient care by leading clinical services, ensuring quality and compliance while managing interdisciplinary teams. Drive strategic goals and enhance operational efficiency in a dynamic home...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$238K - $341K *

Help us elevate healthcare by supervising and training primary care providers, ensuring top clinical outcomes, and fostering an engaged team culture while managing patient care in a collaborative envi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Elevate laboratory operations by managing logistics, compliance, and safety in a dynamic research environment. Collaborate with scientists to streamline processes and ensure a well-functioning lab tha...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Make your mark at the forefront of healthcare operations by leading the strategic oversight and growth of urgent care and occupational health, ensuring exceptional service delivery, compliance, and co...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $145K *

Drive the operational core of People functions, leading a team in Total Rewards, performance management, and employee relations. Be the subject-matter expert while managing day-to-day people services...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $145K *

Lead the charge in People Operations, overseeing Total Rewards, performance management, and employee relations. Manage a skilled team while providing hands-on support and strategic direction across mu...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $144K *

Drive the rehabilitation program's success by ensuring compliance, delivering comprehensive mental health services, and leading a dedicated team. Your expertise will shape client care and program deve...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $167K *

Shape the future of mental health services by overseeing our rehabilitation program, ensuring compliance, and leading a dedicated team to provide comprehensive care for clients with severe mental disa...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by leading a dynamic clinical team in home health. Drive patient outcomes, ensure compliance, and foster professional growth while enjoying a stable work-life balance in a supporti...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $140K *

Contribute to transformative fundraising efforts by managing donor relationships, strategizing solicitations, and collaborating with teams to enhance philanthropic support for mental health initiative...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Elevate operational efficiency by leading mobile healthcare program implementation, managing complex projects, and coordinating cross-functional teams to ensure successful service delivery and communi...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$146K - $282K *

Lead impactful marketing strategies to drive B2B and B2C growth, enhance brand awareness, and optimize performance in a two-sided marketplace, fostering cross-functional collaboration and data-driven...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$146K - $282K *

Drive transformative B2B and B2C marketing strategies that enhance brand presence and user engagement across our dual marketplace. Lead a high-performing team, optimize multi-channel acquisition, and...

Salt Lake City, UTRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $116K *

Empower compliance and quality in Medicare utilization management. Lead audits, assess risks, and collaborate with teams to ensure adherence to CMS regulations while driving process improvements and s...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.