Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Associate Director of Research Operations
$130K - $150K *
Advance your career by providing strategic leadership in oncology and hematology research operations. Oversee clinical trials, ensure regulatory compliance, and collaborate with physician leaders to e...
2 weeks ago
DIRECTOR PRACTICE OPERATIONS II
$111K - $178K *
Champion operational excellence by leading clinic practices, enhancing quality, and fostering collaboration among stakeholders to drive effective healthcare delivery across multiple regions...
Today
Director, Oncology Customer Experience Operations
$151K - $268K *
Lead the charge in enhancing customer experience by advocating for service excellence, collaborating across departments, and driving strategic initiatives to elevate patient and healthcare professiona...
2 weeks ago
$176K - $285K *
Champion the integration and advancement of Advanced Practice Providers, ensuring their voices shape organizational decisions while enhancing professional development and optimizing care delivery acro...
2 weeks ago
$176K - $285K *
Advance your career by leading the integration and development of Advanced Practice Providers. Collaborate with medical leadership to enhance training, optimize practice, and drive professional growth...
2 weeks ago
$129K - $160K *
Oversee and optimize clinical trial operations, ensuring adherence to regulations and timelines. Lead cross-functional teams, manage budgets, and mentor junior staff while driving innovative solutions...
2 weeks ago
$110K - $130K *
Lead clinical operations in a renowned healthcare facility, managing nursing staff and ensuring compliance with policies. Drive effective care systems and promote infection prevention practices while...
2 weeks ago
$110K - $130K *
Empower a dedicated nursing team by overseeing daily operations and ensuring compliance with care standards. Lead initiatives in infection prevention and staff development while fostering a collaborat...
2 weeks ago
Regional Director of Clinical Operations
$95K - $115K *
Elevate your career by leading clinical operations and enhancing person-centered care across communities. Drive compliance, training, and quality outcomes while collaborating with nursing staff to ens...
Today
Director, Global Pharmacovigilance Operations Lead
$185K - $232K *
Drive pharmacovigilance operations globally, ensuring high-quality case management and compliance. Lead strategic projects, collaborate cross-functionally, and enhance processes to deliver impactful r...
3 days ago
$180K - $220K *
Drive exceptional clinical care for veterans through diagnosis, treatment, and oversight while fostering collaborative relationships. Achieve clinical excellence by adhering to guidelines and ensuring...
Reposted 3 weeks ago
$180K - $220K *
Make your mark at a mission-driven clinic focused on delivering exceptional care to veterans. You'll provide direct clinical support, oversee patient care quality, and collaborate with VA partners to...
Reposted 3 weeks ago
Associate Director, Strategy & Operations - US Market Access & Reimbursement
$145K - $175K *
Unlock strategic excellence by spearheading operations within Market Access & Reimbursement. Drive change, enhance coordination, and deliver high-impact materials while collaborating with cross-functi...
Reposted 3 weeks ago
Associate Director, Clinical Supply
$175K - $185K *
Manage clinical drug product supply for study programs, ensuring compliance and effective collaboration across teams and vendors. Develop strategies, forecasting tools, and address supply challenges t...
2 weeks ago
$100K - $120K *
Shape the future of healthcare by leading a network of treatment centers, driving operational excellence, and fostering high-performing teams to enhance patient care and community engagement across di...
2 weeks ago
$135K - $160K *
Unlock your potential by leading complex client engagements, ensuring delivery excellence through strategic program management. Collaborate with diverse teams and build lasting client relationships wh...
1 week ago
$88K - $92K *
Lead the management of clinical services for substance addiction programs, overseeing staff and operations to ensure compliance, deliver quality care, and maintain strong community relationships. Driv...
3 weeks ago
Clinical Operations Specialist
$100K *
Elevate clinical operations across senior living communities, providing guidance and oversight while ensuring quality standards are met. This role requires extensive travel and a commitment to fosteri...
Today
Clinical Operations Specialist
$100K *
Manage clinical operations across senior living communities, ensuring quality care and compliance. Provide guidance and oversight during staff vacancies while conducting audits and supporting wellness...
Today
$135K - $160K *
Join a team that's redefining People Operations by leading strategic initiatives in benefits, payroll, and automation. Drive impactful change while managing a high-performing team and collaborating ac...
6 days ago
Director of Operations (Registered Nurse)
$80K - $95K *
Empower your career by leading operations in a dynamic correctional healthcare environment. Collaborate with multidisciplinary teams to enhance service delivery and ensure compliance while fostering p...
2 weeks ago
$203K - $249K *
Elevate product operations by defining and enhancing the Product Development Lifecycle, integrating AI practices, and fostering cross-functional collaboration to drive efficiency and innovation in pro...
2 weeks ago
$100K - $104K *
Oversee and enhance program operations, ensuring compliance and quality in service delivery. Lead staff development, manage workflows, and support recovery-oriented services while fostering a culture...
2 weeks ago
Medical Affairs Director - Movement Disorders
$260K - $290K *
Lead strategic medical initiatives for Multiple System Atrophy, guiding cross-functional teams in the U.S. medical strategy, scientific communication, and external engagement, while ensuring complianc...
3 weeks ago
Director, MH Lab - Clinical Svcs Admin
$125K - $150K *
Lead the charge in developing operational and financial strategies for laboratory services, ensuring compliance and quality standards while fostering interdisciplinary collaboration and driving growth...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.