Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Senior Applications Administrator
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Optimize collaboration and data governance by managing Microsoft 365 services, focusing on SharePoint Online and data protection. Partner with teams to enhance compliance, security, and operational ef...
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Lead the visual narrative of client brands by delivering exceptional design solutions across multiple channels. Collaborate with diverse teams to uphold high standards and participate in innovative pr...
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Director, Business Development
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Transform your career by driving new business growth in enterprise accounts. Leverage your expertise in IT sales to identify key opportunities, build trusted relationships, and deliver strategic solut...
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Manager Operational Quality Control
$79K - $127K *
Join a team that's dedicated to enhancing electronic enrollment solutions. Lead operational performance, manage a high-performing team, and drive innovation through emerging technologies while ensurin...
Today
Senior Site Activation Manager (US/CANADA)
$107K - $213K *
Join a team that's redefining clinical research by leading site activation strategies and ensuring efficient study start-up activities. Collaborate globally to drive operational excellence and mentor...
5 days ago
$100K - $120K *
Champion impactful People Projects by managing cross-functional initiatives, fostering collaboration, and driving measurable outcomes. Help shape the future of HR processes and project management in a...
2 weeks ago
$147K - $220K *
Drive the success of clinical study projects by managing timelines, budgets, and quality standards. Collaborate with teams and clients to ensure project objectives are met while fostering a culture of...
2 weeks ago
$147K - $220K *
Optimize project delivery by leading clinical study initiatives, ensuring quality, budget, and timelines are met. Collaborate with teams and clients to drive success in complex global trials while man...
2 weeks ago
SSA - Associate Director, AI & Applied Solutions
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Regional Sales Director - Cleveland
$180K - $215K *
Drive regional sales success by leading launch execution, building high-performing teams, and fostering customer relationships. Leverage strong business acumen and collaborative skills to achieve sale...
6 days ago
Associate Manager, Clinical Claims
$109K - $136K *
Drive accurate, evidence-based clinical claims while collaborating with Marketing, Legal, and Clinical teams. Build and manage the claims framework and evidence library to support bold, compliant mark...
2 weeks ago
Director of Network Programs (Sr. Product Manager) - Remote
$112K - $193K *
Champion the development of a new Provider Data Management Platform, leading strategy, design, and implementation. Oversee user interface and data architecture, ensuring seamless integration and gover...
2 weeks ago
Healthcare Tech Manager - Epic Revenue Cycle Performance Improvement
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Optimize healthcare revenue cycle processes by leading Epic transformation initiatives. Drive improvements in patient access, financial clearance, and digital engagement, collaborating with stakeholde...
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$95K - $115K *
Unlock the potential of implementation science as a Senior Program Analyst, driving quality improvement and program evaluation initiatives. Manage processes, databases, and reporting to enhance projec...
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Elevate your career by developing and executing impactful paid social media campaigns. Collaborate with cross-functional teams to optimize strategies, leveraging analytics to maximize reach and ROI wh...
3 days ago
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Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...
2 weeks ago
$216K - $318K *
Champion the evolution of AI Platforms, leading a dynamic team to enhance AI integration and productivity. Drive strategic initiatives that empower engineers and elevate member experiences through inn...
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Innovate training solutions for Field Reimbursement Managers to enhance patient access and compliance. Lead strategy development, implement programs, and collaborate across teams to ensure exceptional...
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Shape the future of AI integration by leading complex projects, bridging technical teams and leadership. Drive Agile methodologies, manage risks, and ensure timely deliverables in a dynamic environmen...
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Empower healthcare providers through innovative engagement strategies, utilizing in-person, virtual, and digital tools to enhance patient care and improve experiences for HCPs, caregivers, and patient...
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Director - Computer Systems Validation
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Lead the Computer Systems Validation Program, overseeing validation teams to ensure compliance with regulatory standards while driving modern validation practices and mentoring future leaders in a dyn...
2 weeks ago
Director - Computer Systems Validation
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Manage and mentor validation teams to ensure compliance and timely delivery of computer system validation activities, driving modern practices and supporting audits while collaborating across departme...
2 weeks ago
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Help us shape the future of pulmonary care by leveraging your clinical expertise to drive product development, enhance workflows, and ensure effective solutions for COPD, asthma, and other pulmonary c...
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Accelerate your career by leading the GTM strategy for USMC, driving revenue growth through strategic relationships and innovative solutions. Collaborate with cross-functional teams to address nationa...
2 weeks ago
International and Operational Genetic Counselor
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Contribute to the delivery of preimplantation genetic testing services by providing expert genetic counseling, managing cases, and collaborating with teams to ensure high standards in genetic testing...
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What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.