Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$170K - $220K *

Drive product strategy and development to enhance clinician experience, optimizing patient care through innovative solutions and stakeholder collaboration across a nationwide healthcare network...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape the future of procurement by leading strategic sourcing initiatives, enhancing vendor relationships, and driving financial transparency. Collaborate across teams to streamline processes and leve...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $100K *

Transform virtual learning by leading strategy and development of innovative programs. Collaborate across teams to enhance educational experiences, ensuring quality and scalability while meeting diver...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$129K - $162K *

Develop and lead actuarial processes for Medicare Value-Based Care, managing monthly results, payer settlements, and special projects. Collaborate with cross-functional teams to enhance analytics and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$143K - $193K *

Accelerate progress at the forefront of data-driven transformation in life sciences. Collaborate with leadership to shape and execute enterprise data architecture initiatives, ensuring scalable, trust...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $147K *

Shape your career by leading data integration initiatives that drive enterprise-wide consistency and governance. Collaborate with stakeholders to deliver trusted, scalable data products while ensuring...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K *

Elevate client success by leading innovative training programs that enhance learning experiences. Drive product adoption and satisfaction through tailored onboarding and ongoing education, ensuring cl...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$268K - $348K *

Transform the U.S. sales landscape for a revolutionary therapy by leading and scaling a dynamic sales organization. Architect and execute strategies that drive exceptional performance and enhance cust...

Hampton, NJRemote

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$145K - $175K *

Unlock potential by serving as a strategic advisor to enterprise clients, guiding them through complex stakeholder environments with predictive intelligence and data-driven insights to drive impactful...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$210K - $250K *

Transform the legal landscape by leading regulatory strategies in healthcare, managing compliance, and advising on critical legal matters, while building and shaping a high-performing legal function w...

RemoteRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $117K *

Elevate your career by leading SDTM programming activities, ensuring quality deliverables, and collaborating cross-functionally to optimize clinical data transformation in a dynamic environment...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $168K *

Lead the charge in shaping and executing product strategy for B2B learning solutions, driving innovation and market impact while collaborating with cross-functional teams to deliver high-quality produ...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$116K - $193K *

Lead the charge in defining and executing the product strategy for AI and analytics, driving innovation across pharmacy management platforms. Collaborate with cross-functional teams to deliver scalabl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Unlock potential by driving financial growth and brand recognition through strategic partnerships across the medical sector. This role involves collaboration, negotiation, and sales strategy implement...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $200K *

Lead the charge in achieving regional sales objectives and executing strategic business plans. Develop key customer relationships and collaborate with cross-functional teams to drive innovative soluti...

Minnesota, USRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Join a high-performing team to drive client success and account growth by managing Regional Account Managers and Client Success Managers, ensuring exceptional service and operational excellence across...

Charlotte, NCRemote

4 weeks ago

  •   5 - 7 years exp.  •   Staffing

$117K - $161K *

Drive impactful clinical intelligence initiatives by analyzing AI opportunities, conducting feasibility studies, and collaborating with cross-functional teams to enhance patient care and operational e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$222K - $255K *

Lead the biostatistical strategies that support impactful medical communication efforts. Collaborate cross-functionally to provide scientific expertise, develop publication strategies, and ensure meth...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Shape the future of K-12 sales by leading a dynamic team of Account Executives. Drive performance through strategic planning, precise forecasting, and collaborative initiatives to achieve growth targe...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Deliver impactful leadership in Sales Operations, driving revenue growth and operational excellence. Collaborate with senior executives to enhance sales productivity, analytics, and process adoption a...

Durham, NCRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $110K *

Optimize user experience by managing Salesforce administration, enhancing platform functionality, and driving user adoption. Collaborate with teams to support business needs and ensure seamless integr...

Dallas, TXRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock potential by leading regional operations across multiple venues, driving revenue growth, talent development, and guest experience. This role demands strategic oversight, accountability, and a c...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $121K *

Champion legal operations excellence by driving process improvements, metrics establishment, and AI integration to enhance workflow efficiencies and support the Legal team in dynamic, fast-paced envir...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Advance your career as a Telehealth Clinical Supervisor, providing leadership and clinical oversight to therapists delivering IOP-level care. Collaborate with a dedicated team to enhance patient outco...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.