Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Manager, Pharmacovigilance (US)
$90K - $178K *
Drive excellence in pharmacovigilance by leading teams and ensuring compliance with global safety regulations. Influence patient safety initiatives while managing project delivery across diverse clini...
6 days ago
Manager, Pharmacovigilance (US)
$90K - $178K *
Drive excellence in pharmacovigilance by leading teams and projects, ensuring compliance and safety across clinical trials. Leverage scientific expertise and operational oversight to mentor profession...
6 days ago
$182K - $198K *
Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...
1 week ago
Dir, MAPS (Market Access Patient Services)/Medical Data Partnerships Lead
$185K - $344K *
Join a team that's redefining market access through innovative data partnerships. Lead strategic collaborations, ensure data compliance, and drive insights that enhance decision-making and patient ser...
Reposted 3 days ago
$180K - $220K *
Transform medical strategies by leading a team of experts, ensuring compliance and scientific accuracy in communications, and fostering client relationships to drive innovative healthcare solutions...
2 weeks ago
Senior Manager, Virtual Care Operations
$120K - $140K *
Shape the future of healthcare operations by leading a dynamic team, ensuring optimal performance and patient satisfaction across a 24/7 Care Concierge function while driving continuous improvement an...
1 week ago
Associate Director, Strategic Planning
$110K - $130K *
Join a team that's redefining strategic planning in healthcare. Collaborate with experts to develop innovative, multichannel strategies, driving insights and brand growth while leading diverse project...
2 weeks ago
Director, Commercial CMC Programs
$150K - $180K *
Empower the execution of CMC strategies by collaborating across teams to enhance production, streamline operations, and drive commercial success for innovative therapeutics and diagnostics, ensuring a...
Reposted 3 days ago
Director, Commercial CMC Programs
$150K - $180K *
Lead the charge in developing and executing CMC strategies to optimize manufacturing processes and commercial operations, ensuring alignment with project goals through effective collaboration across t...
Reposted 3 days ago
$206K - $268K *
Lead the charge in advancing nephrology clinical programs through strategic design, execution, and analysis of clinical trials, ensuring compliance with Good Clinical Practices while collaborating wit...
3 weeks ago
Quality Operations Manager (Contract)
$100K - $120K *
Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...
2 days ago
Medical Director, Musculoskeletal (MSK) Programs
$280K - $305K *
Join a team that's redefining musculoskeletal (MSK) care by designing innovative, scalable solutions to improve patient outcomes and delivering high-quality, empathetic care to diverse populations wit...
4 weeks ago
Marketing Sr Director: CareerMD
$146K - $282K *
Drive transformative B2B and B2C marketing strategies that enhance brand presence and user engagement across our dual marketplace. Lead a high-performing team, optimize multi-channel acquisition, and...
3 weeks ago
Senior Director, Clinical Diagnostics and Precision Medicine
$242K - $403K *
Lead global companion diagnostics strategy, integrating diagnostic plans with clinical development and regulatory objectives. Drive execution across therapeutic programs, ensuring alignment with patie...
2 weeks ago
Associate Director, Field Execution Lead
$152K - $283K *
Deliver impactful field execution by bridging strategy and operations, ensuring initiatives achieve success through proactive risk management and collaboration across teams, all while enhancing accoun...
Reposted 3 weeks ago
Senior Manager, Sales Operations
$115K - $120K *
Lead the charge in driving operational excellence and strategic enablement across global Inside Sales teams, enhancing commercial effectiveness and delivering exceptional client value through innovati...
1 week ago
Associate Managed Care Liaison Director
$206K - $282K *
Join a dynamic team to leverage clinical expertise in managed care, enhancing access to Neurocrine products. Collaborate with stakeholders, deliver impactful presentations, and drive strategic initiat...
3 weeks ago
Medical Affairs Director, Psychiatry Pipeline
$250K - $342K *
Accelerate progress at the forefront of medical strategy, spearheading core deliverables for pipeline molecules while leading cross-functional collaborations in neuroscience and psychiatry. Drive impa...
3 weeks ago
Director, Drug Safety Physician
$280K - $311K *
Optimize safety evaluations within our Drug Safety team to drive innovative strategies for monitoring and managing clinical risks, ensuring compliance and maintaining high-quality standards in pharmac...
3 weeks ago
$136K - $214K *
Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...
4 days ago
Sr Director/Director, Neurology Patient Marketing
$251K - $307K *
Champion innovative patient marketing strategies that drive engagement and awareness for a first-in-class therapy in Becker muscular dystrophy, collaborating across teams to enhance patient experience...
Reposted today
Director, Medical - Clinical Research Scientist
$177K - $338K *
Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...
Reposted 6 days ago
Manager of Clinical Engagement
$115K - $130K *
Join a team that's redefining clinical engagement by leading strategic initiatives to enhance clinician pipelines, improve hiring processes, and foster partnerships across multiple regions, driving or...
2 days ago
Associate Director, Field Launch & Change Surge
$145K - $270K *
Drive stability by providing surge support for product launches and critical changes, ensuring effective execution and alignment across operations. Collaborate with teams to enhance readiness and swif...
Reposted 1 week ago
Director, Clinician Experience
$115K - $183K *
Lead initiatives to enhance clinician engagement and retention across diverse disciplines. Drive strategic improvements for workflow optimization, career development, and well-being, ensuring clinicia...
Reposted 1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.