Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$134K - $201K *

Drive growth and optimize sales strategies by leading and mentoring a dynamic team. Foster relationships with clients and develop training programs to enhance performance, contributing to market expan...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$156K - $227K *

Elevate executive compensation strategies by designing and leading Total Rewards programs that align with organizational goals, while collaborating with key stakeholders to ensure compliance and effec...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$85K - $90K *

Elevate program effectiveness by supervising staff and ensuring quality care for residents with mental health diagnoses, HIV/AIDS, and substance use histories. Collaborate with clinical teams to devel...

Brooklyn, NYRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $165K *

Elevate project management excellence by leading complex pharmaceutical marketing campaigns, mentoring teams, and ensuring strategic alignment with client objectives while driving operational success...

New York, NYRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive operational excellence by leading engineering, data, and AI teams. Collaborate with stakeholders to translate strategic goals into actionable plans, ensuring high-quality project delivery and te...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$84K - $97K *

Unlock potential by fostering relationships with healthcare practices to enhance performance in value-based care. Collaborate with physicians and managers, utilizing data-driven strategies to achieve...

New Mexico, USRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $170K *

Lead cross-functional initiatives and drive strategic alignment by overseeing project portfolios, enhancing business integration, and ensuring successful change adoption across the organization...

Maine, USRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $180K *

Join us in leading product strategy and execution for a diverse portfolio, enhancing Provider Contracting and Credentialing. Collaborate with cross-functional teams to drive innovation, improve custom...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Join a team that's driving strategic growth and profitability in healthcare solutions. Lead cross-functional initiatives, own P&L, and ensure client success while shaping market strategy and solution...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $105K *

Optimize healthcare support by serving as the primary contact for clinical application issues. Collaborate with clinicians and IT teams to troubleshoot, educate, and resolve technical challenges, ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$189K - $246K *

Champion specialty pharmacy operations by leading account management, trade, and distribution efforts. Drive strategic partnerships and operational improvements to enhance patient access and service q...

San Diego, CARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $236K *

Develop and implement innovative therapeutic approaches to enhance mental health outcomes. Collaborate across departments to evaluate, integrate, and govern emerging treatments, ensuring clinical feas...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$230K - $280K *

Lead a high-performing team to enhance Solutions Consulting, drive cross-functional collaboration and ensure the success of strategic accounts through innovative, accountable deal execution and contin...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$97K - $193K *

Lead clinical research activities by managing site relationships, ensuring compliance, and driving study success through proactive monitoring and collaboration with global teams. Your expertise will e...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading sales strategies in the renewable energy sector. Collaborate with cross-functional teams to engage clients, driving sales growth and building impactful relationships while...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$225K - $325K *

Champion integrated transaction management across a vast global portfolio, driving strategic initiatives and operational excellence while fostering strong client relationships and leading cross-functi...

San Francisco, CARemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$154K - $232K *

Shape the future of operations by leading enterprise-wide transformation and optimizing manufacturing networks. Drive cross-functional initiatives, establish governance, and ensure effective change ma...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $140K *

Empower a dynamic team in optimizing revenue cycle services, driving process improvements, and ensuring compliance while fostering client relationships to achieve operational and financial success in...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $145K *

Drive clinical study strategies and execution, ensuring compliance and quality in research initiatives. Collaborate with stakeholders to develop protocols and manage trials, while mentoring junior tea...

Sunnyvale, CARemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $178K *

Champion quality in In-Vitro Diagnostics and Companion Diagnostics. Lead proactive strategies, ensuring compliance in clinical trials while collaborating with partners to enhance precision medicine in...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$141K - $204K *

Drive strategic growth for DSD by leveraging data, analytics, and tools to enhance operational performance and achieve expansion goals. Collaborate with leadership to support initiatives that elevate...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $130K *

Unlock potential by leading initiatives that enhance behavioral health quality and reduce costs. Collaborate with diverse teams to implement innovative solutions, optimize provider performance, and im...

Phoenix, AZRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in enhancing partnerships within our Collaborative Care Program, focusing on driving referral growth and provider satisfaction through strategic engagement and support at various accou...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing AI and ML capabilities to enhance Medical and Workers' Compensation claims processes. Collaborate with stakeholders to create impactful solutions while building a high-pe...

Somerville, MARemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.