Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Manager, Machine Learning Operations & Delivery
$115K - $175K *
Lead and innovate within our ML Operations team, driving scalable machine learning solutions. Oversee a talented group while ensuring robust integration of ML technologies, optimizing performance, and...
1 week ago
Onboarding Project Manager (OD)
$80K - $95K *
Drive successful onboarding for new customers by managing projects from kickoff to go-live. Collaborate with clients and internal teams to deliver tailored solutions, ensuring a smooth transition and...
6 days ago
Senior Director, Technical Solutions - Quantum
$240K - $310K *
Elevate your career as you lead a team of technical experts to develop innovative strategies that drive customer engagement and support business growth across diverse sectors...
3 weeks ago
Vice President, Pharmacovigilance
$210K - $250K *
Champion the future of drug safety by leading global pharmacovigilance efforts. Drive strategy, ensure compliance, and enhance patient safety through innovative processes and cross-functional collabor...
2 weeks ago
Associate Director, Quality Assurance - Technical
$150K - $195K *
Empower quality assurance excellence by leading GMP oversight for contract manufacturing and validation projects, ensuring compliance and collaboration across technical operations to support drug deve...
2 weeks ago
$164K - $273K *
Join a team that's advancing global scientific engagement through strategic conference planning and execution. Collaborate across functions to elevate medical affairs and enhance the impact of evidenc...
Reposted 2 weeks ago
Associate Director, US Patient Advocacy
$164K - $225K *
Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...
Reposted 4 days ago
$110K - $130K *
Drive business growth by promoting products, managing key accounts, and fostering relationships with KOLs. Collaborate on marketing strategies and ensure compliance while achieving sales targets in a...
1 week ago
Senior Advisor, Regulatory Starting Material
$153K - $268K *
Join a team that's advancing regulatory strategies for drug substance manufacturing. Lead the charge in selecting and justifying Regulatory Starting Materials, ensuring compliance with global guidelin...
Reposted 5 days ago
$95K - $115K *
Unlock client potential by driving adoption and optimizing solutions across legal accounts. Serve as a trusted advisor, ensuring clients maximize their investment in Intapp products while fostering lo...
1 week ago
$80K - $125K *
Join a team that's dedicated to enhancing the customer experience through strategic vendor management and operational excellence. Lead initiatives that drive performance, compliance, and continuous im...
1 week ago
Project Leadership (Clinical Trials) - Homebased
$110K - $130K *
Champion global clinical trials by leading project teams to deliver excellence on time and within budget, ensuring high-quality outcomes that exceed client expectations in the biotech and pharma secto...
5 days ago
$80K - $95K *
Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...
Today
Director of Social Media Operations - Remote
$134K - $230K *
Shape the future of social media strategy and operations by leading enterprise-wide governance, optimizing processes, and driving engagement across teams to enhance digital communications and operatio...
1 week ago
$116K - $167K *
Lead the successful delivery of complex projects, managing resources and stakeholders while ensuring adherence to budget, schedule, and quality standards. Empower teams through mentorship and expert g...
2 weeks ago
Risk and Central Monitoring Associate Manager
$65K - $130K *
Contribute to clinical trial success by leading risk management and central monitoring activities. Collaborate with cross-functional teams to ensure compliance with ICH GCP guidelines and enhance qual...
Reposted 5 days ago
Director, Value Strategy & Marketing
$208K - $281K *
Lead the charge in developing value strategies for Rare Disease and Oncology, aligning payer insights with evidence communication to enhance patient access and coverage across product launches and pip...
3 weeks ago
Director, Talent - Talent Management
$110K - $120K *
Elevate talent management by executing core programs, enhancing employee experience, and driving performance initiatives. Lead cross-functional projects, ensuring accountability and operational contin...
1 week ago
$100K - $125K *
Join a team where you will drive strategic planning and enhance operational frameworks to optimize performance and foster collaboration across departments, contributing to transformative solutions and...
Reposted 3 days ago
$205K - $240K *
Shape the future of oncology as a Senior Medical Science Liaison, creating impactful scientific engagement within hematology and oncology that enhances patient care. Collaborate with KOLs and cross-fu...
Reposted 1 week ago
Senior Program Manager, Technical Program Management
$110K - $130K *
Help us drive strategic initiatives by coordinating cross-functional teams, managing risks, and delivering executive-ready reports to ensure successful program execution and stakeholder alignment...
1 week ago
Medium Enterprise Regional Sales Director - Healthcare
$174K - $261K *
Lead a dynamic sales team driving strategic growth in health care markets. Utilize your deep experience in sales and leadership to coach and mentor Account Executives on complex sales cycles, position...
Reposted 6 days ago
Associate Director of Development, Home Base Program Texas
$90K - $105K *
Shape impactful fundraising initiatives by managing a program to engage individual and corporate donors in support of veterans and their families, driving a mission to enhance health and wellness thro...
Reposted 3 days ago
Client Director - Health Life Sciences
$174K - $197K *
Champion strategic client relationships and lead virtual teams to drive growth in our Health Life Sciences vertical, ensuring exceptional customer experiences and achieving financial targets through i...
1 week ago
Post Acute Specialty Division Manager
$134K - $201K *
Drive growth and optimize sales strategies by leading and mentoring a dynamic team. Foster relationships with clients and develop training programs to enhance performance, contributing to market expan...
Reposted 4 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.