Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$168K - $200K *

Champion client relationships and lead diverse teams in life sciences, driving project success through strategic planning and scheduling expertise. Empower your career with mentorship and a focus on q...

Portland, ORRemote

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$173K - $272K *

Lead the charge in ensuring quality oversight for contract testing laboratories globally, implementing policies and managing performance to meet regulatory standards while safeguarding patient safety...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow your career with a dynamic role focused on promoting MRD testing services, driving strategic business development, and collaborating with healthcare providers to enhance oncology diagnostics acro...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's driving regional marketing initiatives in hematology and oncology. Engage with key thought leaders, execute strategic plans, and leverage local opportunities to enhance brand presen...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead and develop engineering teams focused on clinical data integration and insights. Drive the direction of data pipelines and ensure impactful, equitable health outcomes through effective collaborat...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $138K *

Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive your career with a dynamic role focused on enhancing client success through strategic account management, operational assessments, and tailored solutions, while collaborating with cross-function...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$191K - $305K *

Champion innovative healthcare solutions by leveraging clinical expertise to enhance value-based strategies, drive operational excellence, and foster strategic partnerships for improved member care an...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the Washington operations center to drive revenue growth, optimize staffing, and enhance client relations. Ensure high-quality service delivery while managing performance metrics and overseeing o...

Seattle, WARemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $153K *

Drive product excellence by defining and prioritizing features that enhance clinical solutions. Collaborate with stakeholders to ensure alignment with business goals and deliver value through innovati...

Long Beach, CARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Tackle system build, support, and maintenance for Epic Inpatient Orders. Engage in enhancing workflows and managing inpatient provider billing while participating in upgrade cycles and on-call support...

Nashville, TNRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$145K - $168K *

Drive impactful medical congress operations by leading planning, execution, and cross-functional collaboration. Own vendor relationships and budgets while ensuring compliance and delivering high-quali...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$81K - $129K *

Lead the charge in operational oversight of HIMS coding data quality, guiding coder education activities to ensure compliance, accuracy, and continuous improvement in data management across acute care...

Wilmington, DERemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$211K - $316K *

Empower your career by leading strategic engagement with oncology thought leaders. Drive insights and relationships that shape brand strategy and launch readiness for innovative therapies in Head & Ne...

Princeton, NJRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $127K *

Unlock growth by collaborating with cross-functional teams to drive market strategies, analyze data, and enhance customer engagement in the healthcare ecosystem. Contribute to impactful marketing init...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$171K - $202K *

Drive the creation and oversight of a risk framework that balances growth with security. Partner with cross-functional teams to implement risk strategies operationally, while conveying insights to exe...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $140K *

Pioneer GxP compliance in digital quality management, ensuring software and AI products meet regulatory standards. Collaborate with stakeholders to enhance quality processes and support audits, drivin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $140K *

Lead the charge in developing and executing retention strategies for diverse markets. Collaborate with cross-functional teams to translate insights into actionable plans that enhance member experience...

Long Beach, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$76K - $127K *

Elevate your career by driving impactful marketing strategies for electronic prior authorization solutions. Collaborate across teams to enhance provider engagement and improve patient access, while le...

Columbus, GARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Support clinical studies by assisting teams with tasks like medical monitoring and protocol management. Collaborate across functions and engage with stakeholders to ensure successful trial outcomes wh...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate your career by managing coding operations, ensuring accuracy and compliance across healthcare settings. Lead educational initiatives for staff, optimize workflows, and drive improvements in co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $210K *

Unlock potential by leading a dynamic engineering team to enhance specialty prescription processes. Drive strategic direction, foster collaboration, and ensure delivery excellence while managing multi...

Columbus, GARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $200K *

Champion growth by developing sales strategies, nurturing client relationships, and identifying market opportunities. Collaborate with teams to enhance offerings and drive success in the pharma and bi...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a dynamic team to lead financial strategy and analysis, overseeing a $400M budget. Collaborate with leadership to drive insights and enhance financial planning, while managing a team of analysts...

Boston, MARemote

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$175K - $220K *

Lead and develop a high-performing R&D project management team, overseeing a diverse portfolio of innovative projects. Drive effective execution while mentoring staff and enhancing cross-business proc...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.