Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$93K - $120K *
Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...
2 weeks ago
$210K - $250K *
Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...
1 week ago
$159K - $211K *
Join us in transforming quality operations by leading a robust PACE quality program, ensuring compliance and care excellence while collaborating cross-functionally to enhance participant outcomes and...
3 weeks ago
Director/Sr. Director Clinical Pharmacology
$262K - $284K *
Optimize pediatric drug development strategies as a clinical pharmacology leader, overseeing pharmacometric analyses and regulatory submissions, while translating complex data into actionable decision...
Reposted 3 weeks ago
$110K - $130K *
Join a team that's dedicated to creating impactful medical education content for healthcare providers and patients. Collaborate closely with scientific and account teams to deliver high-quality materi...
4 days ago
Associate Director, Study Start-Up
$110K - $130K *
Lead the charge in clinical study start-up operations, driving team development and ensuring timely site activation. Collaborate cross-functionally to enhance processes, meet regulatory standards, and...
2 weeks ago
Sr. Director, Retrieval Operations (Call Center & Workforce Operations)
$181K - $200K *
Champion transformative call center operations by leading strategic outreach, workforce management, and capacity planning. Drive efficiency and quality through innovative automation and AI solutions w...
4 days ago
DIRECTOR/SR. DIRECTOR, DESIGN - REIMBURSEMENT SUPPORT
$135K - $160K *
Join a team that's dedicated to crafting and implementing effective patient support programs. As a strategic leader, you will drive program design, coordinate stakeholder engagement, and ensure succes...
Reposted 3 weeks ago
Associate Director, Clinical Trial Management - Full-Service
$120K - $150K *
Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...
5 days ago
$220K - $280K *
Lead the charge in medical strategy excellence, overseeing team growth and client relationships while translating complex medical insights into actionable brand strategies across diverse therapeutic a...
2 days ago
Operations Director, Biomarker Programs
$175K - $200K *
Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...
1 week ago
Director, Clinical Programs (IKC)
$115K - $183K *
Shape transformative clinical programs and patient engagement strategies, ensuring sustainable outcomes across care settings. Lead a dynamic team while partnering with executives to enhance patient ex...
Reposted yesterday
$195K - $277K *
Drive innovative clinical oncology studies by designing protocols, collaborating with teams, and ensuring compliance with regulations. Leverage expertise to analyze data, support publications, and mai...
2 weeks ago
Director, Clinical Research and Cancer Center Advisory Services
$175K - $200K *
Drive impactful change in healthcare consulting by leveraging your expertise in clinical operations and research administration. Collaborate with executive leaders to solve complex challenges and fost...
2 weeks ago
Executive Director, Field Operations Strategy & Excellence
$246K - $332K *
Transform the future of field operations by leading strategic initiatives that enhance commercial effectiveness and drive measurable impact across customer-facing teams. Collaborate with cross-functio...
6 days ago
$195K - $341K *
Empower healthcare delivery by leading clinical reviews, provider education, and quality improvement initiatives. Collaborate with teams to enhance member care standards and support compliance with re...
1 month ago
Medical Director, Post-Service Review & Medical Claims Review (MCR)
$195K - $341K *
Engage in clinical oversight and support staff training while ensuring adherence to quality standards and regulatory compliance in a collaborative healthcare environment focused on member care and ope...
1 month ago
Director, Revenue Operations - REMOTE
$130K - $150K *
Join a team that's revolutionizing revenue operations by owning HubSpot, building scalable systems, and driving growth through integrated data management. This hands-on role is pivotal in shaping our...
Reposted 3 weeks ago
Director, Cost of Care Solutions
$129K - $162K *
Unlock potential by leading enterprise-wide Cost of Care solutions. Drive scalability, optimize deployment, and enhance operational effectiveness across diverse markets, collaborating with stakeholder...
Reposted 4 days ago
Director, Data Quality & Integrity (Provider Network Operations)
$156K - $215K *
Drive data quality and integrity initiatives by leading cross-functional teams to enhance provider data management practices, ensuring compliance and operational excellence across the organization...
5 days ago
Associate Director, Neuromuscular, US Patient Advocacy
$126K - $234K *
Elevate patient advocacy efforts by building strategic partnerships within Neuromuscular communities to enhance care and reduce access barriers, ensuring patient insights inform corporate strategy and...
Reposted 3 weeks ago
Sr. Mngr/Associate Director, Process Design & Deployment
$110K - $130K *
Join our team to enhance patient access and streamline operational processes, driving meaningful improvements through data analysis, project management, and collaboration across departments while fost...
Reposted 3 weeks ago
$215K - $408K *
Join a team that's dedicated to enhancing medical management and quality improvement. Collaborate with clinical teams to optimize patient care, support performance initiatives, and drive effective uti...
3 weeks ago
$215K - $408K *
Lead the charge in enhancing medical management and quality improvement. Drive utilization review, collaborate with providers, and implement performance initiatives to optimize care quality and cost-e...
3 weeks ago
Senior Director, Client Success
$150K - $180K *
Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.