Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$256K - $347K *

Lead the charge in ensuring optimal safety standards for Rare Disease products. Establish pharmacovigilance strategies, oversee safety profiles, and engage cross-functional teams to deliver critical t...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Lead the charge in delivering complex federal digital services programs, ensuring strategic direction, operational excellence, and strong customer relationships across multidisciplinary teams while ma...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive business growth by promoting products and managing key accounts. Build relationships with clients and KOLs, ensuring compliance while achieving sales targets. Contribute to marketing strategies...

Jersey City, NJRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$119K - $186K *

Lead the charge in shaping a skills-powered talent ecosystem, driving strategy and governance for enterprise skills and talent marketplace initiatives that enhance workforce planning and career growth...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform credentialing operations by leading a dedicated team to ensure compliance, enhance efficiency, and support provider network growth through strategic oversight and process improvement initiat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead a dynamic team of Field Reimbursement Managers, ensuring operational excellence and strategic support while managing key provider accounts. Drive program performance and compliance, fostering a c...

North Carolina, USRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of compliance by leading a robust program that ensures regulatory adherence, fosters a culture of integrity, and collaborates across functions to mitigate risks and enhance operationa...

North Carolina, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Join a team that's dedicated to enhancing customer experiences by leading onboarding initiatives, managing cross-functional collaboration, and driving process improvements to ensure timely program lau...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $155K *

Transform healthcare by driving the adoption of MRD testing services. Collaborate with clinicians and key stakeholders to expand business opportunities and enhance patient outcomes in oncology diagnos...

California, USRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower your career by providing analytic support for performance improvement and labor productivity initiatives. Collaborate with leaders to develop standards, enhance data integrity, and optimize be...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$192K - $252K *

Champion digital transformation by optimizing medical technology solutions and enhancing HCP engagement strategies. Drive adoption and value realization of innovative tools across Field Medical teams...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate your career by managing charge capture and coding operations, ensuring compliance and maximizing revenue. Lead a diverse team, drive process improvements, and collaborate with stakeholders to...

Wisconsin, USRemote

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to enhancing patient safety through data analysis, audits, and collaboration across departments. Drive improvements in EHR software and support quality initiatives to ensu...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $147K *

Drive clinical project performance by leading teams in the execution of research trials. Collaborate with stakeholders to ensure operational excellence, manage budgets, and mitigate risks while foster...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$97K - $145K *

Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $160K *

Contribute to the evolution of data-driven healthcare products, shaping strategy and execution. Collaborate with cross-functional teams to deliver AI-enabled solutions that enhance clinical outcomes a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Accelerate progress at strategic Federal Civilian accounts by driving growth, developing relationships, and leading capture efforts. Leverage market knowledge to identify opportunities and enhance mis...

Washington, DCRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Champion the successful delivery of projects and technology initiatives by coordinating cross-functional teams and managing risks, ensuring timely and high-quality outcomes that align with business ob...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Elevate clinical research by assisting with study design, medical monitoring, and compliance to ensure effective execution of clinical trials and contribute positively to patient outcomes in alignment...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$275K - $350K *

Transform cancer care by delivering high-quality, evidence-based oncology services via telehealth. Collaborate with multidisciplinary teams to enhance patient outcomes and develop innovative care mode...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Transportation

$230K - $260K *

Oversee regional sales strategies and lead a team to drive oncology product sales. Collaborate cross-functionally to enhance market insights and ensure compliance while fostering team development and...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$230K - $368K *

Elevate global BD Excellence capabilities by defining strategies, leading transformation initiatives, and partnering with stakeholders to drive measurable improvement in operational performance and or...

Franklin Lakes, NJRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$247K - $337K *

Transform the landscape of patient safety by leading medical safety initiatives for gene therapy products, ensuring rigorous safety surveillance and risk management practices while collaborating close...

New Jersey, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.