Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$133K - $210K *
Lead the charge in shaping security operations by architecting SIEM, driving automation, and mentoring a dedicated team. Your expertise will enhance threat detection and incident response, ensuring ro...
2 weeks ago
PBM Clinical Coordinator Supervisor
$80K - $95K *
Advance clinical operations by leading a team of coordinators, ensuring efficient coverage determinations and appeals. Foster professional growth while managing day-to-day activities and resolving esc...
3 weeks ago
Associate Director, Technical & CMC Support (PET Quality Operations)
$139K - $232K *
Drive strategic Quality oversight for CMC activities across the PET portfolio, ensuring compliance with cGMP and regulatory standards. Collaborate with cross-functional teams to enhance product integr...
5 days ago
Account Director, Global Strategic Accounts
$175K - $215K *
Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...
2 weeks ago
Director, US Oncology Marketing Portfolio Strategy (Customer Engagement)
$190K - $300K *
Manage and optimize the digital marketing strategy for oncology products, enhancing customer engagement through innovative digital assets. Lead cross-functional teams to execute comprehensive marketin...
2 weeks ago
Senior Engagement Manager - Medical Affairs
$210K - $258K *
Unlock your potential as a Senior Engagement Manager, leading complex consulting projects for pharmaceutical clients. Drive strategic medical initiatives, foster client relationships, and mentor teams...
Reposted 4 days ago
Senior Safety Physician - CNS (remote)
$222K - $356K *
Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...
Reposted 2 weeks ago
$200K - $230K *
Join a team that's shaping the future of migraine treatment by leading U.S. marketing strategies. Drive brand awareness and engagement through innovative campaigns, collaborating across functions to e...
3 weeks ago
Director, Business Development, US West
$130K - $155K *
Join a dynamic team to develop and execute sales strategies transforming oncology translational science. Drive business opportunities, form strategic partnerships, and manage key relationships while n...
Reposted 5 days ago
$150K - $180K *
Drive strategic sales initiatives across multiple regions, managing a team to achieve $90M revenue goals. Analyze market trends, develop sales plans, and foster key customer relationships to enhance b...
3 weeks ago
VP, Content Expert, Market Access
$160K - $200K *
Shape the future of market access strategy by integrating payer, provider, and patient perspectives. Lead cross-functional teams to develop impactful strategies that enhance therapy positioning and su...
3 days ago
Senior Director, Business Analytics
$160K - $236K *
Analyze and drive commercial analytics strategy, establishing strong insights that empower senior leadership's strategic decisions and enhance business performance across a complex, multi-functional e...
4 weeks ago
Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology
$204K - $340K *
Lead the charge in generating impactful real-world evidence to support oncology products, ensuring alignment with market needs and regulatory requirements while collaborating across teams to drive evi...
1 week ago
Director, Patient Engagement, Experience and Recruitment
$177K - $278K *
Champion innovative patient recruitment strategies to enhance clinical trial engagement and retention. Lead a dynamic team, leveraging data and technology to optimize enrollment across diverse therape...
Reposted 6 days ago
Network Operations Manager, Contracting
$119K - $140K *
Shape the future of network partnerships by managing the lifecycle of contracts, from evaluation to negotiation. Collaborate with stakeholders to ensure alignment with operational standards while nurt...
4 days ago
$100K - $120K *
Elevate your career by leading financial planning and analysis, managing budgets, and driving strategic insights. Collaborate with cross-functional teams to enhance operational performance and deliver...
3 weeks ago
Director, Managed Markets - Regional - Central
$235K - $270K *
Drive your career forward by leading access strategies across the Central region. Manage key payer relationships and ensure launch readiness for rare disease products while collaborating with cross-fu...
1 week ago
Senior Director, Quality Assurance (Remote)
$225K - $275K *
Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...
Reposted yesterday
Director, Organizational Change Management - RT Specialty
$120K - $150K *
Lead organizational change initiatives, driving employee adoption and engagement through strategic communication and training. Collaborate with leaders to assess readiness, mitigate resistance, and en...
1 week ago
$64K - $162K *
Transform creative visions into reality by leading a talented design team, driving innovative strategies, and ensuring high-quality project execution across various media platforms while collaborating...
3 weeks ago
Director, Business Development
$110K - $130K *
Drive growth by shaping strategic partnerships and optimizing processes in a dynamic business development role. Collaborate with teams to enhance e-commerce performance, create lead generation strateg...
Reposted 3 weeks ago
Principal IT Analyst - Veeva RIM
$121K - $161K *
Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...
3 weeks ago
$150K - $195K *
Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...
2 weeks ago
Manager, Case Management (LCSW/LMFT)
$90K - $115K *
Champion clinical excellence by leading and mentoring a dynamic ECM team, ensuring comprehensive patient care and adherence to individualized plans, while collaborating effectively with multidisciplin...
Reposted 3 weeks ago
$122K - $203K *
Empower teams by leading data governance initiatives, enhancing data quality, and fostering collaboration across business domains. Drive operational excellence and ensure compliance while developing a...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.