Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Director, Strategic Sales(TMS, WMS & SaaS Focused)
$90K - $170K *
Join a team that's driving strategic sales in TMS, WMS, and SaaS solutions. Lead initiatives to achieve sales targets, develop customer relationships, and promote innovative technology offerings while...
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Drive client engagement and revenue growth by becoming a trusted advisor in Revenue Cycle Management. Leverage expertise to retain and expand business while ensuring client satisfaction across a diver...
2 weeks ago
$108K - $140K *
Drive impactful transformation initiatives by leading complex, cross-functional programs. Collaborate with teams and vendors to ensure successful delivery, manage risks, and align resources to achieve...
3 weeks ago
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Join a team that's driving operational excellence in professional billing for Oncology and Acute Medicine. Lead a dedicated team, enhance revenue cycle performance, and ensure compliance while fosteri...
Yesterday
Senior Pharmacovigilance Associate
$80K - $115K *
Explore a pivotal role in pharmacovigilance, ensuring regulatory compliance and safety management for cancer therapies. Collaborate with cross-functional teams to enhance drug safety processes and sup...
2 weeks ago
$83K - $132K *
Shape the future of clinical appeals by overseeing processes, ensuring compliance, and enhancing efficiencies. Collaborate with teams to analyze data and improve member care outcomes while leading a d...
1 week ago
Executive Director, Technology Strategy & Value Management
$232K - $250K *
Lead the charge in enterprise technology strategy and governance. Spearhead innovative planning and oversight to enhance business outcomes, ensuring alignment with organizational goals and optimizing...
4 weeks ago
Senior Project Manager (Neuroscience)
$122K *
Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...
Reposted 3 weeks ago
Senior Revenue Operations Program Manager
$145K - $160K *
Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...
3 weeks ago
Director, Trade and Distribution
$203K - $280K *
Empower your career by leading U.S. trade and distribution strategies in oncology and rare diseases. Drive operational excellence and partner with cross-functional teams to ensure product availability...
1 week ago
$133K - $210K *
Lead the charge in shaping security operations by architecting SIEM, driving automation, and mentoring a dedicated team. Your expertise will enhance threat detection and incident response, ensuring ro...
2 weeks ago
PBM Clinical Coordinator Supervisor
$80K - $95K *
Advance clinical operations by leading a team of coordinators, ensuring efficient coverage determinations and appeals. Foster professional growth while managing day-to-day activities and resolving esc...
3 weeks ago
Associate Director, Technical & CMC Support (PET Quality Operations)
$139K - $232K *
Drive strategic Quality oversight for CMC activities across the PET portfolio, ensuring compliance with cGMP and regulatory standards. Collaborate with cross-functional teams to enhance product integr...
5 days ago
Account Director, Global Strategic Accounts
$175K - $215K *
Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...
2 weeks ago
Director, US Oncology Marketing Portfolio Strategy (Customer Engagement)
$190K - $300K *
Manage and optimize the digital marketing strategy for oncology products, enhancing customer engagement through innovative digital assets. Lead cross-functional teams to execute comprehensive marketin...
2 weeks ago
Senior Engagement Manager - Medical Affairs
$210K - $258K *
Unlock your potential as a Senior Engagement Manager, leading complex consulting projects for pharmaceutical clients. Drive strategic medical initiatives, foster client relationships, and mentor teams...
Reposted 4 days ago
Senior Safety Physician - CNS (remote)
$222K - $356K *
Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...
Reposted 2 weeks ago
$200K - $230K *
Join a team that's shaping the future of migraine treatment by leading U.S. marketing strategies. Drive brand awareness and engagement through innovative campaigns, collaborating across functions to e...
3 weeks ago
Director, Business Development, US West
$130K - $155K *
Join a dynamic team to develop and execute sales strategies transforming oncology translational science. Drive business opportunities, form strategic partnerships, and manage key relationships while n...
Reposted 5 days ago
$150K - $180K *
Drive strategic sales initiatives across multiple regions, managing a team to achieve $90M revenue goals. Analyze market trends, develop sales plans, and foster key customer relationships to enhance b...
3 weeks ago
VP, Content Expert, Market Access
$160K - $200K *
Shape the future of market access strategy by integrating payer, provider, and patient perspectives. Lead cross-functional teams to develop impactful strategies that enhance therapy positioning and su...
4 days ago
Senior Director, Business Analytics
$160K - $236K *
Analyze and drive commercial analytics strategy, establishing strong insights that empower senior leadership's strategic decisions and enhance business performance across a complex, multi-functional e...
4 weeks ago
Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology
$204K - $340K *
Lead the charge in generating impactful real-world evidence to support oncology products, ensuring alignment with market needs and regulatory requirements while collaborating across teams to drive evi...
1 week ago
Director, Patient Engagement, Experience and Recruitment
$177K - $278K *
Champion innovative patient recruitment strategies to enhance clinical trial engagement and retention. Lead a dynamic team, leveraging data and technology to optimize enrollment across diverse therape...
Reposted 6 days ago
Network Operations Manager, Contracting
$119K - $140K *
Shape the future of network partnerships by managing the lifecycle of contracts, from evaluation to negotiation. Collaborate with stakeholders to ensure alignment with operational standards while nurt...
5 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.