Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Project Manager II, Global Project Leadership
$95K - $115K *
Drive the successful delivery of complex global clinical trials, overseeing cross-functional teams and ensuring compliance with GCP and regulatory standards while managing budgets and timelines to exc...
2 weeks ago
Director, Qualified Success Architecture
$171K - $273K *
Empower revenue teams by building and leading a world-class Success Architecture team. Drive implementation, adoption, and technical credibility while fostering strategic partnerships across Product...
1 week ago
Project Manager- CARDIOVASCULAR (US/CANADA)
$112K - $222K *
Shape your career by leading clinical project management for global trials. Drive cross-functional collaboration, ensure compliance, and meet project deliverables while fostering effective teamwork an...
Reposted 5 days ago
Senior Operations Manager, One Medical - Dist Ops- Field, NorCal Healthcare Ops
$109K - $147K *
Drive operational excellence by leading diverse teams, enhancing member experience, and ensuring compliance across multiple healthcare locations. Collaborate with partners to implement innovative solu...
2 weeks ago
Manager, Medical Education (REMOTE)
$110K - $130K *
Innovate medical education programs for healthcare professionals, ensuring effective training on cardiovascular devices. Collaborate cross-functionally to enhance learning experiences and maintain hig...
1 week ago
AVP Clinical Documentation (Orchestration Works)
$150K - $250K *
Unlock potential by leading innovative clinical documentation initiatives that enhance quality, compliance, and revenue cycle outcomes. Collaborate with cross-functional teams to redefine workflows an...
5 days ago
$80K - $110K *
Drive client success by managing relationships with small to medium accounts, leveraging data for insights, and identifying growth opportunities. Collaborate with internal teams to enhance service del...
Reposted 2 weeks ago
$80K - $110K *
Transform client relationships by driving engagement and optimizing healthcare outcomes through strategic planning, data analysis, and proactive issue resolution. Collaborate with internal teams to en...
4 days ago
Implementation Manager - Data Solutions
$91K - $145K *
Shape the future of data solutions by leading complex pharmacy claims and physician-level data integrations. Collaborate with cross-functional teams to deliver high-quality, scalable solutions that me...
2 weeks ago
Health Economics & Outcomes Research (HEOR) Lead
$198K - $230K *
Drive innovation in metabolic health by integrating clinical expertise with cutting-edge technology, collaborating with diverse teams to enhance product offerings that support health insights in a dyn...
Reposted 1 week ago
$227K - $385K *
Elevate member care by overseeing utilization management and evaluating treatment appropriateness. Collaborate with multidisciplinary teams, ensuring compliance with clinical standards and regulations...
Reposted 6 days ago
$80K - $95K *
Empower our rehabilitation team by leading operations, ensuring compliance, and enhancing patient care. Drive financial success and foster strong relationships with staff and clients while maintaining...
2 weeks ago
FSP - Project Manager II / Sr. Project Manager - Oncology & Ophthalmology
$140K - $185K *
Lead global project management efforts, ensuring timely delivery and quality standards while fostering client relationships and team collaboration. Drive operational excellence in clinical research, p...
2 weeks ago
Senior Manager, Strategic Growth
$110K - $130K *
Lead the charge in expanding into new healthcare verticals by developing and executing go-to-market strategies, managing partnerships, and driving campaign performance. Collaborate with cross-function...
1 week ago
Director of Clinical Quality and Outcomes (BCBA-D Preferred)
$110K - $130K *
Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...
Reposted 3 weeks ago
Director, Strategic Sales(TMS, WMS & SaaS Focused)
$90K - $170K *
Join a team that's driving strategic sales in TMS, WMS, and SaaS solutions. Lead initiatives to achieve sales targets, develop customer relationships, and promote innovative technology offerings while...
4 days ago
$150K - $180K *
Drive client engagement and revenue growth by becoming a trusted advisor in Revenue Cycle Management. Leverage expertise to retain and expand business while ensuring client satisfaction across a diver...
1 week ago
$108K - $140K *
Drive impactful transformation initiatives by leading complex, cross-functional programs. Collaborate with teams and vendors to ensure successful delivery, manage risks, and align resources to achieve...
3 weeks ago
$80K - $113K *
Join a team that's driving operational excellence in professional billing for Oncology and Acute Medicine. Lead a dedicated team, enhance revenue cycle performance, and ensure compliance while fosteri...
Yesterday
Senior Pharmacovigilance Associate
$80K - $115K *
Explore a pivotal role in pharmacovigilance, ensuring regulatory compliance and safety management for cancer therapies. Collaborate with cross-functional teams to enhance drug safety processes and sup...
2 weeks ago
$83K - $132K *
Shape the future of clinical appeals by overseeing processes, ensuring compliance, and enhancing efficiencies. Collaborate with teams to analyze data and improve member care outcomes while leading a d...
1 week ago
Executive Director, Technology Strategy & Value Management
$232K - $250K *
Lead the charge in enterprise technology strategy and governance. Spearhead innovative planning and oversight to enhance business outcomes, ensuring alignment with organizational goals and optimizing...
4 weeks ago
Senior Project Manager (Neuroscience)
$122K *
Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...
Reposted 3 weeks ago
Senior Revenue Operations Program Manager
$145K - $160K *
Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...
3 weeks ago
Director, Trade and Distribution
$203K - $280K *
Empower your career by leading U.S. trade and distribution strategies in oncology and rare diseases. Drive operational excellence and partner with cross-functional teams to ensure product availability...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.