Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$177K - $338K *

Champion DMPK project leadership by ensuring high-quality data delivery and supporting drug candidate progression through innovative modeling and cross-functional collaboration in a dynamic biotech en...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Lead the charge in clinical excellence and patient safety, driving strategic initiatives across health IT. Oversee a multidisciplinary team, ensuring integration of clinical insights into product deve...

Georgia, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$207K - $277K *

Lead the charge in enhancing global ERP delivery excellence, driving governance, quality, and continuous improvement across teams. Foster collaboration and optimize resource utilization to ensure pred...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $256K *

Join a team that's redefining CMC strategies in life sciences. You'll engage with industry leaders, drive software adoption, and shape market narratives to enhance product lifecycle management and ope...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by leading centralized resources and programs, driving operational excellence, and fostering a quality mindset across teams. Collaborate with management to enhance patient support...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$228K - $285K *

Shape the future of market access by leading strategic account initiatives, fostering key relationships, and driving collaboration across teams to enhance product access and reimbursement in the oncol...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$273K - $372K *

Lead strategic clinical evaluations and collaborations to enhance drug development opportunities, while providing expert clinical insights across multiple immunological disorders and supporting cross...

New Jersey, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$217K - $271K *

Launch your career by owning the national Field Excellence model, managing operations for a groundbreaking oncology therapy. Collaborate with sales leaders to enhance prescriber access and streamline...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$300K - $350K *

Join a team that's driving innovation in early clinical development. Lead cross-functional strategies and execution for a high-priority program, ensuring alignment and decision-making to advance a pot...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $150K *

Unlock new business opportunities by strategically engaging with key stakeholders in the Healthcare and Commercial Real Estate sectors. Collaborate cross-functionally to drive targeted campaigns and e...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $120K *

Elevate project outcomes by providing expert guidance in Cerner analysis, design, and implementation. Collaborate with clients and teams to address project issues and ensure successful delivery while...

Chicago, ILRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$182K - $208K *

Join a team that's driving statistical leadership in clinical development. Lead biostatistical efforts for Phase I-IV trials, ensuring quality deliverables and collaboration across functions in a dyna...

Menlo Park, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Drive strategic growth by leading a high-performing team to enhance customer relationships and sales strategies. Oversee National Account partnerships, implement innovative solutions, and achieve ambi...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $135K *

Unlock potential by leading client service strategies that enhance relationships, drive satisfaction, and foster retention. Collaborate across teams to deliver tailored solutions for complex client ne...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$65K - $129K *

Lead the charge in developing competitive proposals and client services, enhancing operational excellence across clinical research programs. Collaborate with global teams to ensure high-quality submis...

Texas, USRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by providing strategic leadership for a national remote case management team, ensuring service excellence, operational consistency, and client satisfaction while collaborating with...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Transform client relationships by leading a dynamic team to achieve financial growth and enhance client experiences across a diverse portfolio. Drive strategic initiatives and foster collaboration to...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $220K *

Elevate your career by managing clinical operations across multiple sites, ensuring performance excellence and strategic partnerships. Lead initiatives that drive growth, enhance client relationships...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Join a dynamic team to lead and enhance billing and coding operations, ensuring quality and compliance across multiple markets. Drive performance, coach leaders, and collaborate cross-functionally to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $173K *

Champion a transformative clinical team, leading 60-70 RNs in delivering exceptional post-discharge care. Drive innovative strategies to enhance patient outcomes and foster a culture of collaboration...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Transform Drug Supply Chain Operations by leading cross-functional teams to establish reliable planning cadences and robust processes, ensuring continuous delivery of medication while driving efficien...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$112K - $222K *

Manage complex clinical trials from initiation to completion, ensuring project success through effective coordination, communication, and teamwork across diverse functional areas and stakeholders. Dri...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Grow your career with a transformative leader shaping scalable patient support programs, guiding cross-functional initiatives, and driving operational excellence to enhance client satisfaction and org...

North Carolina, USRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Unlock potential by managing clinical trial project setups and amendments. Collaborate with teams to ensure client requirements are met, while serving as a subject matter expert to enhance process eff...

Johnson City, TNRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.