Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Senior Manager, Sales Operations
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Senior Manager, Clinical Quality Assurance (Remote)
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Shape the future of clinical quality assurance by overseeing trials, ensuring compliance with GCP and ICH standards, and driving operational excellence across clinical activities within a cross-functi...
Reposted yesterday
Director of Operations, ES - Tampa, FL
$143K - $196K *
Elevate healthcare delivery by leading strategic partnerships and optimizing operations within Oncology service lines. Drive performance through exceptional customer engagement and collaboration acros...
2 weeks ago
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Develop and lead early phase clinical strategies for oncology candidates, ensuring design and execution of clinical trials. Collaborate with internal teams and external experts to drive innovative dru...
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Lead the charge in optimizing complex client portfolios through strategic transaction management. Collaborate with cross-functional teams to execute high-impact real estate initiatives, ensuring align...
Today
Lead, Operations Strategy - Specialty Services Implementation
$90K - $100K *
Join a dynamic team to drive the implementation of innovative service lines, enhancing clinician and patient experiences. Collaborate cross-functionally to optimize operations and lead initiatives tha...
1 week ago
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Senior Director, Medical Information
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Join a team that's dedicated to advancing the Medical Information function for product launches and growth. Lead strategy, vendor partnerships, and scientific content development while ensuring compli...
4 weeks ago
Associate Director / Senior Managing Consultant - Financial Services Operations & Technology
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Transform financial services by leading complex banking operations and technology projects. Collaborate with clients to enhance performance, drive innovation, and shape a new practice within a dynamic...
3 days ago
Clinical Development and Engagement Lead
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1 week ago
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Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...
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Associate Director, Client Engagement
$100K - $120K *
Manage a team of engagement managers to enhance operational effectiveness, drive project execution, and implement innovative solutions. Oversee financial performance and resource allocation while fost...
1 week ago
Director, Copay & Affordability
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Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...
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Project Manager, Business Improvement
$100K - $120K *
Empower your career by driving impactful business improvement initiatives. Collaborate with cross-functional teams to manage projects, analyze data, and enhance operational efficiency in a dynamic env...
2 weeks ago
Associate Director, Regulatory Project Management
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Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...
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Program Administration Director
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Transform program administration for a large federal services initiative, overseeing workforce planning, financial operations, and compliance. Collaborate with diverse teams to enhance operational eff...
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Grow your career with a dynamic team focused on client success, managing relationships, and delivering tailored solutions. Drive satisfaction and retention while collaborating across departments to en...
5 days ago
Director, Inpatient Coding and Compliance
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Shape the future of health information management by leading coding, compliance, and documentation enhancement efforts. Ensure high-quality data management and accurate coding practices to support pat...
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Dir/Sr Dir, Strategy & Delivery (Gen Med - Rare Disease - US and/or Canada)
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Elevate customer engagement by developing and executing strategic study plans, leading cross-functional teams, and ensuring successful project delivery in the rare disease therapeutic area...
2 weeks ago
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3 weeks ago
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5 days ago
Manager of Revenue Cycle & Compliance
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Transform compliance oversight in the DME order-to-payment lifecycle. Lead audits, analyze data, and coordinate payer audits while developing practical controls and reporting to enhance revenue integr...
1 week ago
Senior Manager, Precision Medicine - Clinical Diagnostics
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What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.