Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Program Executive, Drug Development and Commercial
$285K - $325K *
Drive transformational patient impact by leading cross-functional teams and executing strategic drug development programs in an agile environment. Foster collaboration and accountability to deliver in...
Reposted 1 week ago
$187K - $210K *
Champion operational excellence by leading Product Operations, driving innovation, and optimizing workflows. Manage a dedicated team to enhance product delivery, streamline processes, and ensure align...
1 week ago
$195K - $245K *
Champion AI strategy and implementation in healthcare, leading a team to deliver measurable value. Drive business development, client engagement, and practice growth while shaping innovative solutions...
1 week ago
IT Service Delivery Program Manager, Healthcare
$110K - $130K *
Empower healthcare IT delivery by managing a dynamic team, ensuring operational excellence, and driving EMR performance. Collaborate with clinical stakeholders to enhance patient care through effectiv...
6 days ago
Manager, Contact Center and Clinical Operations
$122K - $158K *
Join a team that's dedicated to operational excellence in pharmacy care. Lead clinical operations, enhance patient experiences, and foster a culture of continuous improvement while ensuring compliance...
1 week ago
Associate Director, Marketing, Lung Patient
$186K - $233K *
Shape impactful marketing strategies for lung cancer programs, collaborating with cross-functional teams to drive patient engagement and launch readiness. Lead initiatives that align with brand goals...
Today
Senior Manager, Revenue Operations
$156K - $195K *
Own the end-to-end B2B2C enrollment funnel by transforming data into actionable insights, optimizing processes, and leading cross-functional collaboration to enhance growth and ensure successful membe...
Reposted 3 weeks ago
$205K - $265K *
Empower your career by optimizing sales operations and driving efficiency. Collaborate with cross-functional teams to enhance processes, manage forecasts, and implement strategic initiatives that supp...
1 week ago
Director - QualityOne Strategy Operations
$125K - $300K *
Champion strategic growth by partnering with executive leadership to drive operational excellence, enhance data integrity, and lead cross-functional initiatives that propel business expansion and prod...
6 days ago
Director, Portfolio Performance & PMO
$148K - $175K *
Lead strategic initiatives and operational excellence across client portfolios, ensuring governance, performance management, and continuous improvement. Drive client satisfaction and financial account...
1 week ago
Vice President, CMC Development and Drug Delivery Innovation
$272K - $340K *
Join a team that's driving CMC strategy and execution for innovative therapies. Lead cross-functional efforts in drug and device development, ensuring compliance and operational excellence from clinic...
1 week ago
$150K - $180K *
Shape the future of enterprise-scale cybersecurity by leading vulnerability management initiatives. Drive program strategy, enhance client relationships, and mentor teams to achieve measurable risk re...
Reposted 3 weeks ago
$150K - $180K *
Champion enterprise-scale delivery by leading vulnerability management initiatives, driving program strategy, and fostering client relationships to achieve measurable risk reduction across diverse tec...
3 weeks ago
Clinical Development Medical Director, Early Development - Cardiometabolic
$274K - $371K *
Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...
Reposted 1 week ago
Principal Scientist/Associate Director, Translational Medicine
$190K - $210K *
Collaborate with cross-functional teams to drive clinical biomarker strategy and execution, translating discovery insights into actionable approaches that enhance patient outcomes in early neuroscienc...
4 days ago
Director of Managed Care South
$135K - $180K *
Transform healthcare sales by building strategic relationships within managed care organizations. Drive revenue growth through effective selling and relationship management while maximizing exposure t...
Reposted 5 days ago
Senior Project Manager - U.S. Healthcare Programs
$110K - $130K *
Lead complex healthcare project initiatives, ensuring successful implementation and operational readiness while maintaining high standards of governance. Foster strong partnerships with clients, manag...
Reposted 3 weeks ago
Commercial Operations Manager (Remote)
$115K - $140K *
Drive operational excellence in commercial readiness and support cross-functional teams to ensure effective execution of launch strategies and operational priorities in a dynamic biotech environment...
Reposted today
Vice President Field Operations
$172K - $223K *
Champion operational excellence as a strategic leader, driving performance and financial results across the PacWest Region while ensuring safety, quality, and compliance in a mission-driven environmen...
1 week ago
Associate Director/Director, Medical Affairs - Publications
$175K - $245K *
Lead the strategic publication function for BHB-1893, driving evidence generation and dissemination in hypertrophic cardiomyopathy. Collaborate cross-functionally to ensure timely, high-quality public...
5 days ago
Clinical Workforce Services Compensation Consultant
$101K - $142K *
Transform compensation consulting by developing and administering programs, analyzing market data, and providing expert guidance to clients, all while ensuring project deliverables are met in this dyn...
Reposted 1 week ago
Senior Director, Integrated Risk Management
$126K - $191K *
Lead the charge in implementing an integrated risk framework across the enterprise, enhancing resilience and oversight while guiding teams in risk management, business continuity, and crisis response...
5 days ago
$200K - $232K *
Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...
1 week ago
Associate Director Precision Medicine - Clinical Diagnostics
$176K - $287K *
Contribute to companion diagnostic strategy and development, leading programs from biomarker feasibility to clinical validation. Collaborate across teams to ensure diagnostics align with therapeutic m...
1 week ago
Director, Client Strategy and Growth
$185K - $210K *
Engage with clients to drive retention and growth strategies, fostering deep relationships and collaboration across teams. Leverage market insights to enhance product offerings and ensure client succe...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.