Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Quality & Accreditation Director
$110K - $130K *
Lead the development and execution of a comprehensive Quality Management Program, ensuring NCQA accreditation and regulatory compliance while driving performance improvement initiatives across health...
3 weeks ago
Director, Sales Operations (Remote in USA)
$130K - $160K *
Advance your career by leading transformative sales operations strategies that shape revenue growth. Collaborate with executive leadership to optimize forecasting, performance metrics, and sales techn...
Reposted 3 weeks ago
Group Account Director (Medical Affairs)
$165K - $185K *
Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...
Reposted 1 week ago
$178K - $245K *
Drive end-to-end digital transformation for enterprise supply chains, managing high-stake programs while leading cross-functional teams. Ensure delivery excellence, foster client relationships, and op...
3 weeks ago
Director, Neurology - Thought Leader Liaison (Central)
$245K - $265K *
Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...
1 week ago
Director/Senior Director Commercial Business Development
$175K - $210K *
Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...
5 days ago
Director, Neurology - Thought Leader Liaison (SOUTH)
$245K - $265K *
Drive strategic partnerships with Medical Experts in neurology, enhancing patient care through insights and collaboration. This field-based role requires strong relationship-building and cross-functio...
1 week ago
Chief Medical Officer - CMO - for Optum Community Care Services, CCS - Remote
$292K - $438K *
Empower healthcare excellence by leading clinical programs and teams. Utilize your extensive experience to enhance quality, compliance, and strategic initiatives in a dynamic environment focused on pa...
5 days ago
Associate Director, Field Reimbursement
$211K - $235K *
Drive patient access initiatives by leveraging oncology expertise to navigate reimbursement landscapes, educate stakeholders, and resolve complex access issues, ensuring timely therapy access for pati...
Today
Director, Care Delivery Learning & Development
$161K - $202K *
Unlock potential by leading a dynamic Learning & Development team to enhance clinical and non-clinical training programs, ensuring high-quality patient care through innovative strategies and scalable...
4 days ago
(Senior) Director, Regulatory Affairs CMC
$210K - $305K *
Champion the global CMC regulatory strategy for a pivotal HCM program, ensuring compliance from Phase 3 through launch. Collaborate with cross-functional teams to build robust regulatory processes and...
1 week ago
Director, 503A Provider Relations
$110K - $130K *
Drive growth by leading a team of provider relations representatives, managing key provider relationships, and implementing strategies to enhance service offerings and revenue within the compounding p...
3 weeks ago
$220K - $330K *
Drive medical excellence by bridging clinical insights with risk management, guiding underwriting standards, and ensuring compliance across Life, Disability, and Long Term Care products while collabor...
1 week ago
$175K - $225K *
Lead the charge in shaping strategic program management across a diverse client portfolio. Oversee a team of professionals to ensure excellence in execution, governance, and client engagement while dr...
5 days ago
$90K - $110K *
Unlock potential by managing pharmaceutical programs, ensuring smooth operations, client relationships, and strategic execution while overseeing performance metrics and enhancing team collaboration...
Reposted 3 weeks ago
Associate Director, Field Access Training
$154K - $242K *
Champion training strategies for Field Access Managers, enhancing capabilities and supporting critical brand launches. Collaborate with cross-functional teams to deliver effective training solutions i...
Reposted 2 days ago
$122K - $184K *
Drive operational excellence by leading physician practices in Ohio. Collaborate with clinical and regional teams to enhance performance, accountability, and patient experience while translating data...
1 week ago
Payroll Operations Director - Remote
$134K - $230K *
Champion operational excellence in payroll by leading teams, optimizing processes, and ensuring compliance. Drive strategic initiatives and enhance associate experience while managing complex payroll...
Today
Manager, Patient Services - Client Program Mgmt, Patient Access
$102K - $130K *
Lead the charge in optimizing patient services through effective team management, strategic collaboration, and continuous improvement initiatives. Drive operational efficiencies while ensuring high-qu...
5 days ago
Technical Design Manager - Client Services
$110K - $130K *
Lead the charge in designing and implementing complex operational workflows that enhance service delivery and client experience. Collaborate with cross-functional teams to drive continuous improvement...
5 days ago
$110K - $130K *
Champion clinical trial excellence by managing projects from initiation to completion, ensuring compliance and quality standards while collaborating with cross-functional teams to drive successful out...
3 days ago
$230K - $270K *
Drive the future of AI-powered dental care by building a revenue-driven marketing engine that shapes growth and positions the organization as a category leader across multiple market segments...
Reposted 3 weeks ago
Field Operations Director - AMER
$120K - $150K *
Partner with us to build a scalable sales operations framework across the Americas, enhancing forecast accuracy and pipeline management while fostering strong relationships with field leadership and d...
1 week ago
Manager Professional Billing Coding Operations - Remote
$78K - $113K *
Join us to lead the Professional Coding Operations team, ensuring accurate coding practices and compliance. Collaborate with stakeholders, mentor staff, and drive improvements in coding efficiency and...
1 week ago
Director, Field Effectiveness, Rare Disease and Oncology
$193K - $262K *
Champion the sales force's success by leading a dynamic team focused on optimizing field effectiveness and operational efficiency, driving excellence in performance and insights...
3 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.