Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$134K - $249K *
Champion pharmacy excellence by leading strategic initiatives and operational oversight for a pharmacy benefit management program. Drive quality, compliance, and innovation while collaborating with cr...
3 weeks ago
Director, Enterprise Portfolio Management
$150K - $195K *
Drive change management initiatives that enhance employee engagement and operational efficiency. Collaborate across teams to ensure successful adoption of technology and policy changes, while providin...
3 weeks ago
$165K - $215K *
Shape the future of value-based payments by leading product strategy, overseeing team development, and driving market innovations within a collaborative, cross-functional environment...
3 weeks ago
$100K - $120K *
Champion clinical monitoring excellence by leading project teams, ensuring adherence to standards, and fostering collaboration. Drive operational success through effective oversight, training, and str...
Today
Director, Product Management Financials
$150K - $180K *
Shape the future of healthcare technology by leading product management efforts. Drive innovation and strategy while mentoring a team to enhance software solutions that improve patient outcomes and op...
Yesterday
Director, Software Engineering
$150K - $180K *
Innovate by leading software engineering excellence and AI adoption; manage cross-functional teams to develop impactful tech solutions while maintaining hands-on involvement with proof-of-concept proj...
1 month ago
Medical Director - Addiction Medicine (Telehealth)
$200K - $240K *
Unlock potential by leading high-quality, evidence-based substance use disorder treatment as a physician leader. Collaborate with cross-functional teams to shape clinical governance and enhance servic...
3 weeks ago
Director, Market Growth Strategy, Molecule to Market (Biologics)
$185K - $256K *
Elevate the market growth strategy for biologics research, driving software adoption and AI use cases. Collaborate with global teams and engage with industry leaders to shape the future of molecular t...
1 week ago
Regional Medical Director, 24/7 Care
$230K - $240K *
Inspire excellence by leading provider support initiatives, enhancing satisfaction, accountability, and clinical quality. Drive process innovation and mentorship in a dynamic environment, ensuring com...
2 weeks ago
Vice President of Product Management
$235K - $265K *
Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...
2 weeks ago
$133K - $191K *
Empower the HR technology landscape by leading strategy, governance, and optimization of HRIS. Collaborate with cross-functional teams to enhance processes, ensure data integrity, and drive digital tr...
2 weeks ago
$98K - $164K *
Champion client success by leading post-sale implementations and ensuring ongoing account performance. Collaborate with cross-functional teams to translate client needs into actionable insights, drivi...
4 days ago
Senior Director, Innovation and Delivery
$200K - $250K *
Drive critical initiatives by navigating ambiguity, building effective operating models, and ensuring measurable outcomes in a dynamic environment. Engage with leadership to implement AI solutions and...
Reposted 3 weeks ago
Director, Neurology - Thought Leader Liaison (WEST)
$220K - $250K *
Shape the future of neurology by building partnerships with Medical Experts, generating insights, and collaborating across teams to enhance patient care and drive innovation in a dynamic healthcare la...
Reposted 4 days ago
Administrative Director, Operations (Home Health)
$110K - $130K *
Elevate operational excellence in home care by overseeing daily functions, ensuring compliance, and driving quality improvement initiatives. Collaborate with stakeholders to achieve strategic goals wh...
2 weeks ago
$143K - $208K *
Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...
Today
National Account Director, Community Oncology
$245K - $290K *
Champion strategic relationships in community oncology to enhance market access for innovative therapies. Drive account strategies, negotiate contracts, and collaborate cross-functionally to ensure op...
Today
Director, Field Access and Reimbursement - Psych
$150K - $180K *
Shape the future of patient access by leading a high-performing team focused on strategic execution and measurable impact in the Psychiatry field. Drive compliance, culture, and collaboration across f...
1 week ago
Clinical Development Medical Director, Obesity/Cardiovascular
$274K - $371K *
Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...
Reposted 1 week ago
Sr. Advisor, Molecular Pharmacology - Neuroscience
$129K - $231K *
Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...
Reposted today
Director / Senior Director / Executive Director, Regulatory Affairs
$210K - $275K *
Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...
Reposted 1 week ago
Manager, Training & Workflow Optimization
$79K - $94K *
Lead the development and execution of training programs while optimizing workflows to enhance provider experiences. Collaborate with stakeholders to ensure effective training delivery and continuous i...
4 days ago
$150K - $180K *
Lead the charge in driving strategic growth by managing a high-performing sales team, refining sales strategies, and fostering a culture of excellence to achieve ambitious revenue goals...
1 week ago
$80K - $90K *
Transform client relationships by managing the transaction lifecycle, ensuring customer satisfaction, and collaborating with internal teams to drive profitability and service excellence. Leverage your...
2 weeks ago
Manager, AI & Workflow Operations - Licensed (RN, NP, PA, or MD, RPh, PharmD)
$100K - $120K *
Transform healthcare delivery by leading operations for a growing telehealth practice. Collaborate with clinical teams to enhance patient care through innovative solutions and efficient workflows, ens...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.