Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$150K - $178K *
Optimize biosample operations in clinical trials, ensuring quality and compliance while collaborating with cross-functional teams to enhance sample management and drive innovation in biosampling strat...
1 week ago
Director, Marketing Operations
$124K - $205K *
Optimize marketing operations by managing systems, data, and processes to drive pipeline growth. Lead HubSpot and Salesforce integration, oversee lifecycle reporting, and implement AI solutions while...
3 weeks ago
Senior Director, Medical Affairs - Oncology
$210K - $331K *
Optimize team performance by leading field-based medical professionals, managing budgets, and executing Oncology support plans. Drive compliance and foster development through effective coaching and p...
2 weeks ago
Strategy and Operations Physician Enterprise Clinical SME
$125K - $235K *
Drive operational excellence in healthcare by leading transformative initiatives, optimizing workflows, and enhancing provider productivity. Collaborate with teams to deliver data-driven solutions tha...
3 days ago
Senior Budget Administrator - Clinical Trials
$100K - $161K *
Advance your career by coordinating clinical trial budgets and coverage analyses. Collaborate with stakeholders to ensure compliance and cost efficiency while mentoring junior staff and enhancing admi...
4 days ago
$110K - $130K *
Drive exceptional service delivery by leading a team of program managers, enhancing patient access to medications, and ensuring operational excellence while fostering a supportive work environment...
1 week ago
$174K - $374K *
Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...
Reposted 1 week ago
Senior Medical Director, Clinical Development
$312K - $444K *
Unlock potential by leading and executing clinical trials for oncology products. Collaborate with teams to design studies, monitor safety, and ensure compliance with regulations while driving innovati...
2 weeks ago
Client Experience Product & Operations Lead
$100K - $120K *
Make your mark at a dynamic organization by enhancing client experiences through innovative solutions. Lead operations, tackle escalations, and build systems that ensure seamless care journeys while d...
2 weeks ago
Director of Business Development
$110K - $130K *
Lead the charge in expanding strategic partnerships and driving growth initiatives with autonomy. Collaborate with leadership to assess market trends, enhance client relationships, and achieve sales t...
3 weeks ago
Associate Director, Business Improvement
$130K - $160K *
Reimagine business improvement strategies as a senior contributor, leading high-impact initiatives across functions. Drive alignment, governance, and measurable outcomes while influencing stakeholders...
1 week ago
Director, Commercial Project Management
$201K - $251K *
Join us to lead cross-functional project management in a dynamic biotech environment. Drive global commercialization initiatives, ensuring alignment and execution across teams while enhancing operatio...
1 week ago
Provider Operations Manager - Credentialing
$73K - $115K *
Grow your career with a dynamic team focused on optimizing provider operations. Lead credentialing initiatives, implement AI solutions, and enhance workflows while ensuring compliance and operational...
Today
$115K - $168K *
Lead the charge in federal grant management for the 988 Suicide & Crisis Lifeline, overseeing compliance, budgeting, and operations. Collaborate across teams to ensure effective grant administration a...
2 weeks ago
Director, Marketing Operations & Sales Enablement
$186K - $279K *
Accelerate commercial growth by overseeing marketing operations and sales enablement strategies. Collaborate with cross-functional teams to optimize processes, enhance lead generation, and implement i...
3 days ago
Chief Operating Officer, Illinois Health Practice Alliance
$207K - $392K *
Advance your career by managing operations and driving growth, ensuring client satisfaction while developing key relationships with providers and stakeholders in a dynamic and supportive environment...
Reposted 2 weeks ago
Project Manager, Delivery Lead
$95K - $115K *
Elevate project delivery by leading cross-functional teams in Interactive Response Technology, ensuring client satisfaction and timely execution while managing risks and fostering continuous improveme...
2 weeks ago
Sys VP Clinical and Industry Trials
$180K - $220K *
Empower innovation in clinical trials by developing strategies, overseeing operations, and cultivating partnerships. Drive excellence in research, enhance compliance, and manage a high-performing team...
Reposted 4 days ago
Director, Process Optimization Lead
$171K - $231K *
Champion operational excellence and innovation within the P&SM function, driving strategic planning, resource management, and cross-functional collaboration to enhance efficiency in clinical study exe...
Reposted 1 week ago
Senior Director, Regulatory Operations
$265K - $295K *
Lead the charge in regulatory operations, managing submissions and compliance strategies to ensure global regulatory alignment and efficiency across multiple teams and projects...
Reposted 5 days ago
Manager, Client Strategy & Operations
$100K - $120K *
Join a team that's focused on enhancing client delivery and relationship growth. Drive data-driven strategies and cross-functional collaboration to optimize post-sale operations, ensuring exceptional...
Reposted 1 week ago
Manager, Regulatory Affairs (Clinical Labeling)
$110K - $130K *
Take ownership of IMP labeling processes, ensuring compliance with global regulations and quality standards while collaborating cross-functionally to support clinical trial timelines and enhance label...
3 weeks ago
Senior Clinical Trial Manager (CTM)
$168K - $188K *
Oversee and manage clinical trials from protocol development to final report, ensuring compliance with GCP and regulatory standards. Collaborate with cross-functional teams to enhance research efficie...
Reposted 3 weeks ago
$107K - $145K *
Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...
2 weeks ago
Senior Manager, Engagement Operations
$110K - $130K *
Drive your career by building innovative member journey systems from the ground up. Collaborate cross-functionally to design and launch CRM workflows, automations, and campaigns that enhance engagemen...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.