Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$140K - $150K *

Lead the charge in advancing oncology-focused medical strategies, leveraging clinical expertise and strategic insights to drive impactful marketing initiatives and foster key relationships within the...

New York, NYRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$149K - $224K *

Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$272K - $340K *

Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$268K - $302K *

Lead strategic clinical pharmacology initiatives, guiding drug development from early to late stages. Collaborate cross-functionally, ensuring robust pharmacological strategies and regulatory complian...

Cambridge, MARemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Unlock potential by providing operational leadership for global clinical studies, ensuring timely delivery, compliance, and quality. Collaborate with cross-functional teams and manage vendor relations...

Boston, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a dynamic team to lead the strategy and delivery of innovative reporting and analytics solutions that enhance client value and patient services. Drive insights, foster collaboration, and elevate...

Mason, OHRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $160K *

Drive client success in our lab network by managing relationships, ensuring renewals, and identifying growth opportunities. Collaborate across teams to enhance processes and improve client experiences...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team to drive physician recruitment efforts, manage client relations, and source candidates. Leverage extensive networks while ensuring a seamless hiring journey that aligns with client...

Dallas, TXRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$400K *

Lead a dynamic sales team to drive adoption of innovative stroke recovery technology. Collaborate with healthcare providers to enhance patient outcomes while developing sustainable referral networks a...

Atlanta, GARemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$197K - $239K *

Join us to lead AI-driven innovation in real-world data strategy, translating business priorities into actionable insights. Drive data intelligence and collaboration across teams to enhance evidence g...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$297K - $367K *

Grow your career with a pivotal role driving hospital data integration and compliance. Lead execution of clinical data operations, build relationships, and ensure secure data handling while shaping a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate operational efficiency by leading shared service improvements and cross-functional collaboration to enhance patient and provider experiences while driving team performance and process excellen...

North Carolina, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $265K *

Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$82K - $126K *

Elevate clinical research by leading the Pre-Award team to ensure compliance, budget accuracy, and timely activation of trials while driving process improvements and maintaining high performance metri...

Tampa, FLRemote

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$185K - $344K *

Lead transformative initiatives by embedding adoption strategies from design to deployment, ensuring sustainable outcomes across teams and processes. Collaborate with leaders to enhance change readine...

East Hanover, NJRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Transform medical affairs by driving scientific excellence and strategic initiatives in ophthalmology. Collaborate with cross-functional teams to enhance field readiness and optimize engagement across...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $224K *

Drive growth in the Neurodegenerative Disease sector by developing strategic partnerships with health systems and academic centers, leveraging existing relationships to create innovative solutions tha...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $160K *

Accelerate growth by leading strategic sales initiatives in the Ambulatory Surgery Center market. Build executive partnerships, drive customer satisfaction, and expand market share through innovative...

Texas, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive strategic initiatives and operational excellence across a global portfolio, partnering with leadership to enhance business performance and deliver measurable outcomes in oncology and rare diseas...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Drive the future of healthcare operations by leading a $300M portfolio, fostering physician partnerships, and executing growth strategies while managing financial and operational performance for a dyn...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$113K - $197K *

Drive optimal enrollment operations through strategic leadership, overseeing member lifecycle processes, compliance, and data integrity while managing vendor partnerships and operational transformatio...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading pharmacy operations, enhancing client engagement, and driving continuous improvement initiatives. Oversee a team of clinical professionals to ensure high-quality pharmacy s...

Nashville, TNRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.