Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
$134K - $184K *
Unlock potential by joining a dynamic team focused on radiation oncology, where you'll design treatment plans, collaborate with oncologists, and ensure precise dose delivery while utilizing advanced i...
2 weeks ago
$80K - $95K *
Engage in high-quality legal research to support law firm clients, focusing on intellectual property matters. Utilize advanced research tools to deliver accurate results and synthesize findings into a...
3 weeks ago
Account Executive - Philadelphia, PA
$84K - $102K *
Drive sales growth by developing strategies to expand market share in healthcare sectors. Engage with clients, promote products, and resolve reimbursement issues while achieving sales goals and mainta...
3 days ago
$85K - $100K *
Join our team as a Clinical Director to lead and enhance inpatient behavioral health services. Oversee clinical staff, ensure quality care, and promote evidence-based practices in a supportive environ...
Today
$90K - $110K *
Join our Mobile Quality Engineering team to ensure the quality and reliability of iOS applications. Collaborate with cross-functional teams to validate features, troubleshoot issues, and enhance user...
3 weeks ago
$125K - $150K *
Transform creative vision into impactful strategies, leading teams to deliver exceptional work that meets and anticipates client needs while fostering a positive agency culture and driving professiona...
Reposted 1 week ago
Principal Scientist, Scientific Workflows & Agentic Cheminformatics
$117K - $201K *
Transform drug discovery by leading innovative cheminformatics workflows, collaborating with cross-disciplinary teams to enhance decision-making and accelerate scientific advancements in medicinal che...
1 week ago
Distinguished Engineer, AI Security Systems (Remote)
$235K - $350K *
Transform the future of cyber defense by architecting cutting-edge AI systems that autonomously protect against real-world threats. Lead technical direction, mentor teams, and drive innovation from re...
6 days ago
Director, Assistant Staff Counsel
$179K - $280K *
Tackle complex legal management challenges by leading multi-office operations and enhancing organizational excellence. Drive talent development and operational improvements while ensuring high-quality...
4 weeks ago
$160K - $200K *
Drive strategic growth and operational excellence in cardiology, fostering physician partnerships and overseeing clinical and financial performance to enhance patient care and organizational success...
Today
$150K - $180K *
Transform cloud infrastructure by leading strategy, team development, and automation. Drive security, reliability, and cost management while collaborating across functions to enhance operational excel...
1 week ago
$110K - $120K *
Join a dynamic team as you oversee IT operations, user lifecycle management, and security for a growing organization. This hands-on role allows you to set standards and processes while serving as the...
2 weeks ago
Principal, Cloud Solutions Architect
$208K - $235K *
Innovate and lead the development of scalable cloud solutions, ensuring high engineering standards and strategic architecture. Collaborate with cross-functional teams to translate business needs into...
3 weeks ago
Director of Applied AI Engineering
$207K - $290K *
Elevate your career by leading a dynamic Applied AI team, transforming innovative AI solutions into production-ready systems within a regulated financial environment, while collaborating across depart...
2 weeks ago
$204K - $327K *
Drive innovative legal solutions as a key partner for AI and product teams, providing comprehensive guidance on regulatory challenges and product development. Collaborate cross-functionally to ensure...
Yesterday
Director of Nursing - Pediatrics
$71K - $120K *
Lead the charge in pediatric nursing excellence by overseeing operations, mentoring staff, and ensuring compliance with care standards. Drive quality improvement initiatives while fostering a compassi...
3 weeks ago
$128K - $145K *
Support the full life cycle of vendor contracts, from negotiation to execution. Collaborate with stakeholders to manage legal risks and ensure compliance in a fast-paced environment, focusing on healt...
Yesterday
$95K - $115K *
Join our Endocrinology team to provide exceptional patient care in a dynamic outpatient setting. Collaborate with physicians and advanced practice clinicians to manage diverse endocrine disorders and...
2 weeks ago
$88K - $105K *
Optimize verification strategies and lead hands-on testing to enhance product reliability. Collaborate across engineering disciplines to translate requirements into effective test methods, driving imp...
1 week ago
Account Specialist, Eugene, OR
$160K - $192K *
Engage with healthcare providers to drive commercial performance and product adoption. Collaborate with cross-functional teams to support launches and optimize patient access, ensuring impactful relat...
1 week ago
Senior Statistical Programmer/Analyst Consultant (Need solid oncology background) Remote in US
$110K - $130K *
Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...
1 week ago
$95K - $115K *
Unlock potential by leading innovative sales training programs for orthopedic trauma and joint reconstruction, enhancing clinical knowledge and sales skills to drive growth and effectiveness in a dyna...
Yesterday
Director, Technology Alliances
$190K - $275K *
Join a team that's driving strategic technology alliances to transform integrations into robust commercial partnerships, focusing on co-selling, joint marketing, and stakeholder alignment while leadin...
Reposted 2 weeks ago
Account Executive - Business Development Sales, Healthcare SaaS
$150K - $180K *
Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...
Today
Director Service Coordination and Long-Term Services and Supports, Geisinger Health Plan
$110K - $130K *
Join us to lead strategy and implementation for long-term services and supports, ensuring compliance and enhancing participant experience in a dynamic healthcare environment. Drive impactful partnersh...
5 days ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.