Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

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$160K - $200K *

Lead the charge in financial strategy and operational excellence, driving growth and sustainability for a mission-driven organization. Collaborate with leadership to implement innovative solutions and...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$112K - $249K *

Elevate your career as a Senior Product Owner, driving product vision and prioritization within a dynamic team. Engage with stakeholders to deliver business value and ensure client satisfaction in the...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$112K - $249K *

Take ownership of the UK Payments Hub roadmap, driving delivery across various payment schemes while collaborating with engineering and compliance teams to ensure alignment with regulatory requirement...

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Drive strategic partnerships by building trusted client relationships, leveraging market insights, and delivering tailored solutions that enhance growth and client satisfaction across diverse organiza...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Accelerate your career by driving revenue growth with enterprise clients. Leverage your sales expertise in the fashion industry to build relationships, identify needs, and deliver tailored solutions t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $315K *

Lead the charge in driving profitable growth and client satisfaction across a multi-office A/E/C division, overseeing strategic planning, talent management, and operational excellence to ensure long-t...

1 week ago

  •   15+ years exp.  •   Technical Services

$80K - $95K *

Advance your career by managing and optimizing infrastructure and cloud services for a diverse user base. Collaborate with IT leadership to implement secure, scalable solutions while ensuring reliable...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Join a team that's dedicated to supporting adults with serious mental illnesses. Lead a multi-disciplinary ACT team, providing comprehensive assessments, medication management, and therapeutic support...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Join a team that's dedicated to enhancing compliance excellence through strategic oversight of operations, risk management, and audit processes. Collaborate with leadership to drive regulatory complia...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Shape compliance excellence by overseeing post-closing functions, managing risks, and driving continuous improvement. Collaborate with stakeholders to ensure adherence to regulations and enhance the C...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $130K *

Join a team that's redefining Workers' Compensation filings. Leverage your expertise to manage complex engagements, navigate state regulations, and serve as a trusted advisor, ensuring compliance and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$76K - $97K *

Lead the charge in delivering innovative interior design solutions while overseeing complex projects. Utilize advanced design skills and a collaborative approach to ensure excellence and sustainabilit...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$130K - $140K *

Accelerate the growth of colorectal cancer screening solutions by engaging healthcare providers and driving product adoption. Collaborate with partners while strategically planning to maximize market...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $100K *

Transform patient care by delivering high-quality behavioral healthcare. Play a key role in a supportive environment that values work-life balance and professional growth, while enjoying flexible sche...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $175K *

Unlock your potential by leading risk management initiatives, collaborating with stakeholders to assess project risks, and developing comprehensive risk strategies. Engage clients and enhance your exp...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$100K - $120K *

Build strong communities by leading development initiatives, mentoring teams, and ensuring operational excellence. Collaborate with stakeholders to enhance resident engagement and drive successful com...

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Unlock potential by delivering high-quality behavioral healthcare in a flexible, supportive environment. Join a dedicated team focused on patient care and professional growth, with opportunities for b...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Lead the charge in driving commercial performance by engaging healthcare providers, building relationships, and executing territory business plans to ensure patient access to innovative therapies and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Deliver leadership and governance for global clinical study management, ensuring projects meet timelines and budgets while fostering collaboration and operational excellence across teams and stakehold...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive the M&A strategy by leading the full transaction lifecycle, from sourcing to integration. Collaborate with executive leadership to identify growth opportunities that enhance enterprise value and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Engage in a dynamic leadership role managing outpatient clinic operations, ensuring high-quality patient care and efficient financial performance while collaborating with medical and community partner...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Advance healthcare leadership by driving operational excellence and strategic growth in a critical care environment. Lead with integrity, ensuring exceptional patient care and compliance while fosteri...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.