Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

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$116K - $229K *

Drive the future of AI-driven employee experiences by leading implementation projects, optimizing workflows, and collaborating with cross-functional teams to enhance HR and IT service delivery through...

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$167K - $196K *

Drive risk mitigation strategies by analyzing account takeover and scam threats. Collaborate cross-functionally to enhance user protection and platform integrity, shaping metrics and prevention tactic...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Shape clinical quality and network management by leading a dedicated team to enhance provider relationships, ensure compliance, and drive performance improvement across the healthcare network. Engage...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Optimize food service operations by managing budgets, ensuring quality standards, and maximizing profits. Lead a team to maintain compliance and deliver superior service while driving operational exce...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$210K - $250K *

Transform the payments landscape by leading strategy and execution across product, engineering, and operations. Drive growth and innovation in embedded payments, ensuring alignment and measurable outc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Join a team that's dedicated to providing exceptional primary and preventative care for long-term care patients, managing acute conditions, and collaborating with healthcare professionals to enhance p...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Empower innovation by leading the architectural vision for clinical technology platforms. Drive scalable, secure, and compliant solutions while integrating AI/ML capabilities and ensuring regulatory a...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate your career as a vital member of a multidisciplinary team, providing comprehensive patient care across various settings. Engage in medical management, physical exams, and develop tailored care...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $288K *

Accelerate progress at the forefront of digital health solutions by leading product strategy and execution for a transformative app, enhancing user experiences and driving stakeholder value through in...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$79K - $93K *

Empower your career by leading a dynamic clinical support team, managing operations, and enhancing patient care in a collaborative environment. Drive improvements while ensuring compliance and fosteri...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$64K - $96K *

Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $105K *

Empower healthcare delivery by ensuring coding accuracy as you analyze medical records, identify improvement opportunities, and enhance AI diagnostic models to uphold high-quality standards in inpatie...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $220K *

Join a team that's redefining strategic sourcing for commercial categories. Lead initiatives that drive value, enhance supplier performance, and align with business goals while managing vendor relatio...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$74K - $112K *

Unlock potential by providing expert speech therapy services in home health, assessing patient needs, developing treatment plans, and collaborating with healthcare teams to enhance communication and c...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by providing strategic leadership for a national remote case management team, ensuring service excellence, operational consistency, and client satisfaction while collaborating with...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Drive strategic client relationships and operational excellence for global healthcare accounts, ensuring optimal service delivery and exceeding performance targets through proactive solutions and coll...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $181K *

Engineer innovative commercial strategies that drive growth and enhance contract management for a fast-evolving portfolio in the controls services domain. Collaborate with cross-functional teams to op...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Shape the future of data protection by leading a high-performing team of analysts. Drive incident response, enhance security strategies, and collaborate with clients to mitigate risks in a fast-paced...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$195K - $215K *

Lead the charge in brand strategy, inspiring teams and fostering innovative solutions in a dynamic healthcare advertising environment, focused on advancing compelling communications and effective clie...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$220K - $240K *

Drive strategic growth and operational excellence in a B2B SaaS environment, overseeing P&L, leading a diverse team, and integrating scalable subscription models with custom enterprise solutions to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $130K *

Join a dynamic team to lead and enhance billing and coding operations, ensuring quality and compliance across multiple markets. Drive performance, coach leaders, and collaborate cross-functionally to...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $110K *

Accelerate progress at pediatric mental health care by leading clinical quality assurance and supervision, mentoring clinicians, and providing evidence-based therapy to children and families in a full...

Pennsylvania, USRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Shape the future of patient care by leading a dynamic team in a fast-paced clinic. Drive operational excellence, enhance patient experiences, and support staff development in a nationally recognized a...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Elevate our admissions operations by leading a dynamic team, optimizing workflows, and enhancing client experiences. Drive strategic initiatives to improve conversion rates and ensure compliance with...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$209K - $238K *

Accelerate transformative tech solutions by leading diverse teams in building innovative cloud-based systems. Collaborate cross-functionally to optimize performance and enhance user experiences, empow...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.