Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$125K - $150K *

Join a dynamic outpatient surgery center as a CRNA, providing essential anesthetic care in a supportive environment. Enjoy flexible shifts with no nights or weekends, while collaborating with a dedica...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Make your mark at the forefront of neonatal care, leading a dedicated team to enhance patient outcomes and foster a culture of excellence in a dynamic NICU environment. Drive clinical education and su...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Engineer cutting-edge blockchain infrastructure for financial markets. Drive architecture, design proofs of concept, and ensure interoperability while collaborating with teams to meet institutional re...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Champion the future of patient care by delivering expert pharmaceutical services, ensuring medication safety, and collaborating with healthcare teams to enhance clinical outcomes in a dynamic hospital...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Design and implement robust Identity and Access Management solutions for enterprise environments, enhancing security and efficiency through automation, integrations, and compliance with regulatory sta...

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$156K - $260K *

Empower cyber defense initiatives by designing, implementing, and optimizing advanced security solutions. Lead investigations, mentor teams, and enhance detection capabilities to proactively mitigate...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Partner with us to ensure the quality and reliability of our web-based administrative solutions. Collaborate with cross-functional teams to validate features, identify defects, and maintain comprehens...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Unlock potential by leading the design and planning of innovative healthcare facilities, enhancing patient care and operational efficiency through strategic renovations and new constructions, while co...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $120K *

Empower patient care by collaborating with interdisciplinary teams to deliver high-quality oncology services. Utilize clinical judgment and evidence-based practices to enhance patient outcomes in a su...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $175K *

Unlock your potential as a hands-on leader in customer service operations, driving performance and quality across teams. Collaborate with cross-functional partners to enhance processes and empower you...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$70K - $100K *

Join a team that's dedicated to optimizing Epic Resolute Professional Billing. Support daily operations, troubleshoot issues, and enhance workflows while collaborating with analysts and users to ensur...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $200K *

Unlock potential by defining and guiding enterprise architecture, integrating cloud, infrastructure, and security to support business priorities. Lead modernization efforts and influence cross-functio...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Innovate within a dynamic team, driving impactful projects and solutions that enhance operational efficiency and foster growth across multiple departments. Your expertise will shape strategic initiati...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Partner with us to enhance veterinary medical support through education, training, and product expertise. Engage with veterinarians and sales teams to ensure compliance and promote American Regent Ani...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Manage territory business plans to drive sales performance, engage healthcare providers, and support product launches. Collaborate with cross-functional teams to optimize patient access and ensure com...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock product potential by leading the development of innovative food safety solutions. Collaborate with cross-functional teams to address complex industry challenges and drive scalable product strat...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in enhancing patient and workplace safety through strategic risk management initiatives. Collaborate across departments to identify risks, ensure compliance, and foster a culture of sa...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$91K - $179K *

Drive operational excellence in manufacturing through digital transformation solutions, working with cross-functional teams to enhance efficiency, quality, and visibility across production processes w...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$91K - $179K *

Join a team that's transforming manufacturing through digital solutions. Drive operational efficiency and enhance production processes while collaborating with cross-functional teams to build robust s...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$180K - $220K *

Drive clinical excellence by providing medical expertise across therapeutic areas, ensuring safety and integrity in clinical trials. Collaborate with project teams and senior management to enhance cli...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion advanced analytics initiatives to enhance supply chain efficiency, drive strategic decision-making, and improve mission readiness through actionable insights and predictive modeling across di...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Explore forensic pathology by conducting postmortem examinations, determining causes of death, and collaborating with law enforcement and legal entities. Engage in community education and mentorship w...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$62K - $112K *

Transform member engagement by proactively addressing concerns, coordinating solutions, and enhancing satisfaction. Collaborate with cross-functional teams to drive improvements and ensure a seamless...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$125K - $150K *

Join a dynamic team to advance pediatric hematology through clinical care, teaching, and innovative research. Engage with students and fellows while contributing to impactful scholarship in a collabor...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.