Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$250K - $286K *

Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential by managing data assets and implementing strategies for effective data governance. Collaborate with stakeholders to enhance data lifecycle management and optimize database perfor...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Help us drive business development in oncology by leading strategic partnerships and optimizing resources to enhance clinical outcomes and market potential for our innovative diagnostic and therapeuti...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive operational excellence in ambulatory practices, ensuring patient-centered care and fiscal viability. Collaborate with leadership to enhance strategic, operational, and financial performance whil...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Elevate your career by leading managed care strategies and negotiations. Drive value-based care initiatives across practices to optimize revenue and enhance growth. Collaborate with cross-functional t...

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $120K *

Join a team that's dedicated to delivering exceptional customer service by accurately assessing vehicle damage, coordinating repairs, and ensuring compliance with insurance requirements throughout the...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Lead the charge in transforming finance operations through strategic planning and execution. Build and scale the finance function for a high-growth startup, ensuring resources align with growth initia...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$254K - $382K *

Pioneer innovative clinical strategies as a senior medical leader, driving excellence in study execution and client engagement. Collaborate with cross-functional teams to enhance patient care and oper...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$123K - $157K *

Advance your career by leading strategic sourcing for metals, driving cost savings and supplier performance. Engage with cross-functional teams to influence decisions and ensure supply continuity whil...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$93K - $109K *

Innovate alongside executives by providing strategic support to drive organizational success, manage high-stakes priorities, and enhance workflow efficiency. You'll serve as a vital liaison and truste...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $102K *

Help us empower customers by maximizing their use of embedded payments. Collaborate with teams to drive growth, analyze rates, and ensure success with Shopmonkey Payments, all while adapting to the dy...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$87K - $100K *

Transform your career as a Full-Time Internal Traveler, delivering expert physical therapy across diverse clinics nationwide while enjoying the stability of full-time employment and comprehensive bene...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $122K *

Unlock your potential as you lead financial planning, analytics, and strategic initiatives. Collaborate closely with executives to drive performance improvements and optimize resource allocation, fost...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$112K - $189K *

Join us to ensure safe, effective medication therapy while advancing pharmaceutical care. Collaborate with healthcare teams, educate future practitioners, and support drug-related research to optimize...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Optimize patient recovery as a Physical Therapist in a collaborative, outpatient setting. Benefit from a supportive team while providing individualized care to Workers' Compensation and Personal Injur...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$155K - $264K *

Explore a leadership role that shapes digital identity solutions, enhances client relationships, and drives strategic project developments while mentoring teams and fostering community ties. Join us t...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$95K - $135K *

Transform regional clinic performance by leading clinical readiness initiatives, enhancing team skills, and ensuring quality care across multiple locations. Champion patient safety through audits, tra...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Unlock potential by joining a dedicated team of therapists focused on delivering high-quality behavioral healthcare while enjoying flexible schedules and a supportive work environment...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower a dynamic rehab team by leading clinical programs and ensuring compliance. Collaborate with management to enhance quality care and foster a supportive environment for staff and patients alike...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Transform your legal career by joining a dynamic Real Estate practice. Leverage your expertise in commercial transactions, zoning, and land use while collaborating with seasoned attorneys on diverse r...

Reposted yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $100K *

Join a team that's dedicated to providing individualized orthopedic care, collaborating with diverse patients while fostering professional growth and mentorship in a supportive environment...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $165K *

Drive customer success in Cancer Registry by building relationships, enhancing retention, and translating insights into actionable solutions. Collaborate across teams to improve outcomes and shape bus...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in driving client success by building trusted partnerships, understanding client objectives, and ensuring seamless delivery of services. Collaborate with internal teams to enhance sati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Lead the charge in managing high-severity, complex insurance claims, focusing on EPL and Professional Liability. Serve as a subject matter expert, ensuring compliance and strategic resolution while ad...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Drive pharmacy excellence by leading services, ensuring compliance, and enhancing patient care. Collaborate with healthcare teams while managing staff and operations to optimize performance and qualit...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.