Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$226K - $291K *

Deliver specialized medical expertise in determining causes of deaths under medical examiner jurisdiction, investigating violent or suspicious cases, and collaborating with families and agencies to en...

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Partner with us to provide comprehensive care for patients with complex upper GI diseases. Collaborate with a multidisciplinary team, ensuring continuity and coordination throughout the patient's trea...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Lead and inspire nursing teams to deliver exceptional patient care in home health settings. Oversee operations, ensure compliance, and foster a culture of excellence while collaborating with interdisc...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$76K - $97K *

Join a dedicated team providing compassionate care in adolescent medicine. This role involves patient assessment, collaboration with families, and adherence to clinical protocols, ensuring high-qualit...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Develop innovative software solutions for implantable medical devices, leading design and implementation while ensuring compliance with regulatory standards. Collaborate with cross-functional teams to...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $100K *

Shape the future of behavioral healthcare by delivering high-quality patient care. Join a dynamic team focused on clinical excellence, professional growth, and work-life balance in a supportive enviro...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $139K *

Join a team that's dedicated to managing compliance initiatives and regulatory audits, ensuring excellence in healthcare standards while collaborating with stakeholders to drive impactful solutions an...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$107K - $142K *

Optimize system performance by leading advanced support initiatives, mentoring teams, and enhancing complex applications. Collaborate across departments to resolve issues and drive operational improve...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$188K - $282K *

Drive the architecture for customer data integration across digital platforms, ensuring secure ingestion and transformation. Collaborate with cross-functional teams to create scalable solutions that e...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Unlock superior patient care by leading a dynamic team while enhancing patient experiences and achieving business success through effective management and strategic initiatives...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$135K - $196K *

Unlock potential by shaping the demo experience through innovative tooling and infrastructure. Collaborate across teams to enhance product communication and drive secure access solutions, all while le...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$207K - $267K *

Unlock potential by leading global procurement strategies, optimizing vendor management, and driving efficiency across technology and software categories while mentoring a high-performing team...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Media

$210K - $250K *

Transform pediatric care by leading a multidisciplinary team in Developmental Behavioral Pediatrics, focusing on comprehensive evaluations and innovative treatments for children with developmental dis...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $300K *

Drive product strategy and lifecycle management, ensuring alignment with market needs and business growth. Lead cross-functional teams to develop, launch, and support innovative medical devices while...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$229K - $267K *

Optimize consumer acquisition strategies to drive growth and innovation across multiple channels. Lead a high-performing team, manage budgets, and define future goals while ensuring effective executio...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate client relationships by delivering tailored financial solutions, driving growth in a fast-paced environment while collaborating across teams to enhance customer satisfaction and community enga...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $100K *

Join a team that's dedicated to delivering high-quality behavioral healthcare. Enjoy flexible schedules and a supportive environment while making a meaningful impact on patients' lives. Grow your care...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Engage in the design and management of enterprise endpoint technologies, ensuring security and efficiency across over 1,000 devices. Collaborate with cross-functional teams to enhance endpoint perform...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $192K *

Drive commercial success by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and enhance patient access to innovative th...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform clinical operations by leading staff and managing resources to ensure quality patient care in general surgery and procedural settings. Collaborate with interdisciplinary teams to enhance pat...

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Transform the landscape of behavioral healthcare by delivering high-quality services. Join a dynamic team focused on professional growth, work-life balance, and innovative care solutions in a supporti...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Lead the visual narrative of client brands by delivering exceptional design solutions across multiple channels. Collaborate with diverse teams to uphold high standards and participate in innovative pr...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$66K - $113K *

Champion enterprise portfolio reporting and analytics, developing insights to drive strategic decision-making and enhance project visibility. Collaborate across teams to create actionable dashboards a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.