Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$87K - $105K *

Transform patient care by leading a dynamic outpatient physical therapy team. Drive clinical excellence, mentor staff, and enhance patient outcomes while fostering a supportive clinic culture and achi...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Shape the future of patient care by providing comprehensive neurology services in a collaborative environment. Engage in clinical evaluations, manage patient care, and contribute to education and rese...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$109K - $174K *

Elevate your career by driving innovation in biomaterials R&D. Collaborate with cross-functional teams to develop and test advanced medical devices, ensuring compliance and enhancing patient outcomes...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$133K - $237K *

Contribute to patient safety by overseeing medical product surveillance, analyzing data, and ensuring compliance with regulations. Collaborate on risk management and support clinical studies to enhanc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$134K - $230K *

Lead the charge in delivering exceptional pharmaceutical care by managing daily operations, coaching staff, and fostering relationships with consumers and clinic partners to enhance service quality an...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform healthcare through innovative AI deployments. As a key technical expert, you'll develop and implement cutting-edge systems that enhance clinical workflows and optimize patient interactions...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$280K - $340K *

Transform regulatory strategy and operations across CMC and clinical activities, leading a high-performing team to ensure compliance and successful product approvals from development through post-appr...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Information Technology

$349K - $396K *

Lead the charge in driving national growth strategies for enterprise employers, managing a top-performing sales team focused on Fortune 500 engagements, overseeing the acquisition lifecycle, and ensur...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Shape the future of clinical care management by leading strategic operations, optimizing processes, and enhancing patient care. Collaborate with teams to drive performance improvements and ensure comp...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Unlock potential by joining a dynamic team of neuropathologists, engaging in anatomic and autopsy pathology, and contributing to residency education and tumor board discussions in a collaborative clin...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$79K - $119K *

Lead the charge in establishing quality standards and testing methods while managing vendor relationships and compliance. Drive process improvements and ensure product integrity through data analysis...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Build lasting relationships and drive customer success by leveraging insights and data to enhance client engagement and retention. Collaborate cross-functionally to inform product improvements and sup...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $192K *

Execute territory business plans to drive commercial performance, engage healthcare providers, and support product launches. Collaborate with cross-functional teams to optimize patient access and ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's dedicated to enhancing internal audit processes. Leverage your expertise in auditing standards and healthcare to drive compliance and efficiency while collaborating across all organ...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by assessing and treating individuals with hearing disorders. Engage in fitting hearing aids, providing auditory training, and conducting related research to enhance patient outcomes...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead transformative projects that enhance performance metrics, driving strategic outcomes and optimizing operational effectiveness while collaborating across business units to execute impactful result...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in delivering exceptional pediatric care by supporting physicians and enhancing patient experiences. Collaborate with a dedicated team to assess, plan, and implement effective treatmen...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower patient care by joining a dedicated team of healthcare professionals. Utilize your pediatric expertise to assess, plan, and deliver high-quality care in a collaborative environment focused on...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $109K *

Advance the future of Building Information Modeling by leading BIM strategies, ensuring model quality, and mentoring teams. Drive innovation through technology initiatives and enhance project delivery...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in advancing clinical science strategies for innovative medical technologies. Collaborate across teams to design studies, analyze data, and communicate findings, ensuring compliance an...

Today

  •   5 - 7 years exp.  •   Healthcare

$140K - $150K *

Drive transformative initiatives in cancer care navigation. Influence strategic partnerships and implement scalable programs that enhance patient access to evidence-based care, ensuring equity across...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$188K - $282K *

Drive design excellence in fintech by leading a team to enhance payment, billing, and timekeeping solutions. Collaborate with cross-functional partners to shape user experiences that empower legal pro...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Accelerate progress at our patient care center by overseeing daily operations, ensuring quality therapy services, and leading a dedicated team. Utilize your clinical expertise to enhance patient outco...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $90K *

Engage with SMB accounts to build pipeline and close value-driven deals. Own your territory, manage sales cycles, and leverage data to drive results. Collaborate across teams to connect solutions with...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$77K - $112K *

Transform patient care by delivering high-quality, in-home nursing services. Collaborate with interdisciplinary teams to provide urgent interventions, education, and support, ensuring a patient-first...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.