Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

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$207K - $346K *

Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $115K *

Help us drive operational excellence in provider data management, ensuring accuracy and efficiency throughout the lifecycle. Collaborate with teams to enhance processes, leverage insights, and impleme...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $187K *

Explore a rewarding role providing in-home health evaluations, fostering relationships to enhance patient care. Travel extensively to deliver personalized health services, ensuring comprehensive suppo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Engage with healthcare services and technology leaders to drive new business growth. Leverage a robust support system to build relationships, execute territory plans, and expand existing accounts whil...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Make your mark at a leading emergency services team, delivering high-quality care in a fast-paced environment. Collaborate with skilled professionals and utilize advanced technology to enhance patient...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $200K *

Join a team that's committed to compassionate veterinary care, working collaboratively in a modern facility with specialized resources, while maintaining a work-life balance and nurturing your profess...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$221K - $335K *

Elevate clinical research by leading innovative studies, ensuring data integrity and patient safety. Collaborate cross-functionally to drive strategic initiatives and enhance clinical development whil...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion the management and execution of complex e-discovery projects, collaborating with legal teams to ensure successful outcomes. Oversee multiple projects while mentoring a team, maintaining quali...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$90K - $110K *

Champion patient care by assisting physicians with examinations, treatments, and referrals. Engage in rounds and provide comprehensive support to enhance patient management and outcomes in a dynamic c...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$277K - $359K *

Drive clinical excellence and professional growth as a Nurse Anesthetist in a dynamic environment. Enjoy flexible scheduling, competitive compensation, and opportunities for leadership and education w...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $189K *

Join a team that's leading provider enrollment operations, ensuring timely onboarding, compliance, and accuracy. Drive strategic initiatives and enhance operational efficiency across networks while co...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Unlock potential by driving new enterprise sales in cybersecurity. Own the full sales cycle, from prospecting to closing, while expanding existing accounts. Collaborate with teams to deliver tailored...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $150K *

Join a team that's dedicated to enhancing clinical support through technical expertise and customer training. Drive product demonstrations and ensure customer satisfaction while collaborating with sal...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Champion exceptional patient care and operational excellence through collaboration, ensuring top-notch optometric services while driving key performance outcomes and fostering a team-oriented culture...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and enhance patient access to innovativ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$86K *

Elevate patient care by delivering comprehensive nursing services in a dynamic float pool environment. Collaborate with interdisciplinary teams to address diverse patient needs and ensure high-quality...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform claims management by leading strategic initiatives, overseeing operations, and driving continuous improvement across a diverse portfolio, ensuring optimal outcomes and compliance while colla...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $94K *

Optimize training and workflow processes by leading program development, mentoring trainers, and collaborating with stakeholders to enhance provider experiences and operational efficiency across Care...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion a high-growth sales strategy by developing a results-driven team to achieve revenue targets, expand market presence, and foster strategic client relationships while ensuring continuous improv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower surgical teams by providing comprehensive patient care across multiple specialties. Collaborate with physicians to enhance surgical outcomes through evaluations, procedures, and patient manage...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $103K *

Drive strategic insights by analyzing data and market trends to optimize pricing and profitability in the Home Equity business, collaborating with cross-functional teams to influence key business deci...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join us to lead strategic procurement initiatives, optimizing vendor management and contract negotiations across a dynamic healthcare network. Drive cost efficiency and enhance clinical quality while...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Transform the landscape of billing compliance by leading a dedicated team in conducting thorough audits, enhancing documentation practices, and ensuring adherence to regulations. Drive continuous impr...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion patient experience initiatives by leading operational oversight and training programs. Collaborate with senior leaders to enhance care perceptions and ensure exceptional service across all pa...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.