Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Dentist Jobs in Pennsylvania

Sort By: Relevance

$300K - $350K *

Join a dynamic team as a Retina Surgeon, providing exceptional ophthalmologic care in a collaborative environment. Contribute to education and research while addressing a growing need for specialized...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive impactful care delivery strategies by collaborating across teams to enhance patient access and operational efficiency in the GU portfolio. Shape scalable solutions that support adoption and opti...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Unlock the potential of patient care as you support an inpatient cancer team, performing diagnostic and therapeutic tasks while advocating for patients and coordinating with physicians to enhance trea...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $160K *

Champion operational excellence by leading teams to enhance efficiency and care delivery. Drive AI integration, manage P&L, and collaborate cross-functionally to support growth and sustainability in h...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead a dynamic nursing team in a fast-paced acute care environment, fostering excellence in patient care and staff development. Collaborate with multidisciplinary teams to enhance clinical practices a...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $160K *

Empower operational excellence across a portfolio of surgical centers. Drive strategic growth, enhance performance, and foster physician partnerships while ensuring compliance and quality standards ar...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$68K - $93K *

Unlock potential by driving sales through strategic customer engagement and relationship management. Utilize digital tools and territory management to enhance customer experiences and achieve sales ta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$222K - $356K *

Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Empower the future of urgent care leadership while practicing medicine. Lead a dedicated team of providers across multiple centers, driving clinical quality and strategic growth in a balanced administ...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive revenue cycle optimization by enhancing Epic Professional Billing workflows, collaborating with stakeholders, and resolving claims challenges to improve overall operational efficiency and ensure...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to creating impactful medical education content for healthcare providers and patients. Collaborate closely with scientific and account teams to deliver high-quality materi...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join our team to shape the future of pharmacy care, impacting older adults' lives through expert medication management and compassionate service. Collaborate with healthcare professionals to ensure op...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Lead the charge in enhancing patient care as a Staff Pharmacist, overseeing medication management, supervising pharmacy technicians, and ensuring compliance with safety standards while making a positi...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $114K *

Join a dedicated team to enhance senior care by leading operations, ensuring quality standards, and fostering a supportive community atmosphere. Collaborate with staff and families to promote positive...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K *

Join a team that's dedicated to providing comprehensive primary care to patients of all ages. As a Family Nurse Practitioner, you'll play a vital role in enhancing community health through preventive...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$92K - $110K *

Shape the future of healthcare as a vital team member, delivering exceptional patient care and collaborating with physicians to enhance practice efficiency and outcomes...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Manage a dynamic radiology team, ensuring high-quality imaging services and operational efficiency while fostering a collaborative environment and driving continuous improvement in patient care and st...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Deliver exceptional patient care by leading skilled nursing initiatives, enhancing quality, and reducing readmissions. Collaborate with healthcare teams to manage complex cases and ensure optimal outc...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Optimize clinical documentation by analyzing billing practices and coding guidelines. Collaborate with specialists to enhance quality and compliance, educate providers, and reduce denials, ultimately...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Join a team that's dedicated to excellence in Dermatopathology, providing essential diagnostic services. Collaborate with skilled professionals in a supportive environment that values teamwork and enh...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$221K - $315K *

Innovate solutions to complex challenges while leading cross-functional teams, overseeing project development. Collaborate with stakeholders to ensure successful delivery and continuous improvement of...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by delivering high-quality anesthesia and pain care services across diverse settings. Collaborate with healthcare teams to ensure optimal patient outcomes while practicing autonomousl...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$360K - $400K *

Join a team that's dedicated to transforming patient care through innovative psychiatric practices. Enjoy flexible schedules and a supportive environment while delivering high-quality outpatient servi...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower brand strategies by providing scientific leadership and insights. Collaborate with multidisciplinary teams to translate complex data into compelling narratives, ensuring accuracy and alignment...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.