Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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1,000+

Dentist Jobs in Oklahoma

Sort By: Relevance

$180K - $215K *

Shape the future of our commercial launch by leading a regional sales team to drive market entry, foster customer relations, and exceed performance goals in a dynamic, cross-functional environment...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $110K *

Join a dedicated team to provide comprehensive medical care, including diagnosis, treatment planning, and patient education across various settings, ensuring optimal health outcomes for assigned patie...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $158K *

Shape the future of Medicaid wellness by leading innovative strategies and solutions that enhance health outcomes for underserved populations. Collaborate with diverse teams to develop impactful progr...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$93K - $159K *

Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$268K - $466K *

Champion early clinical development in a dynamic team. Lead clinical research physician role for first-in-human studies, ensuring compliance and collaboration across scientific and regulatory areas to...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$262K - $404K *

Optimize patient care and operational leadership as you manage Anesthesia APP teams, ensure regulatory compliance, and build strong client relationships while driving growth in practices and enhancing...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Empower patient care through expert image interpretation and guidance in diagnostic radiology. Collaborate on quality assurance, oversee technical standards, and educate staff while ensuring optimal p...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a dynamic team to support product management for government insurance, ensuring compliance and driving strategic initiatives. Leverage your expertise to lead analysis, define requirements, and en...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $90K *

Lead data-driven insights to enhance business performance, collaborating across teams to support strategic initiatives. Utilize technical skills in SQL, Python, and data visualization to drive impactf...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $105K *

Collaborate with clients and teams to manage projects, expectations, and delivery, ensuring high standards and strategic growth in a fast-paced medical affairs environment. Leverage experience to iden...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$193K - $308K *

Join a team that's redefining statistical leadership in clinical research. Drive innovative study designs, enhance drug development effectiveness, and influence critical decisions through data-driven...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $115K *

Join a team that's focused on diversifying paid media channels and optimizing conversion strategies. You'll lead initiatives across affiliate, programmatic, and social platforms to enhance member acqu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $195K *

Unlock patient engagement strategies by integrating insights into drug development. Collaborate with diverse teams to generate evidence, engage with professional societies, and lead initiatives that p...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to optimizing privacy management processes and compliance technology. This role supports platform administration, user engagement, and operational improvements, ensuring e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to delivering exceptional patient-centered care while leading and developing high-performing clinical teams. Drive operational excellence and community impact in a dynamic...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$120K - $145K *

Accelerate commercial growth by defining strategies for product families, collaborating across teams to translate market insights into actionable plans that drive revenue, profitability, and customer...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Unlock your potential by analyzing Medicaid data to enhance program performance, quality, and access. Collaborate with diverse teams to develop insights that drive impactful decisions in healthcare an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $215K *

Elevate regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $144K *

Optimize our data platform by owning end-to-end data engineering projects, leveraging AI coding agents, and ensuring data quality. Collaborate with cross-functional teams to deliver reliable, maintain...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $100K *

Lead the charge in managing nursing staff performance and fiscal operations, ensuring compliance with healthcare standards while fostering a culture of continuous education and improvement within the...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.