Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$150K - $180K *

Transform your career by leading AI initiatives that drive business growth and operational efficiency. Collaborate across functions to embed AI into Rho's core operations, shaping a future where AI en...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$180K - $215K *

Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Engage with key healthcare clients to drive strategic account management, fostering relationships and delivering tailored solutions across GE HealthCare’s diverse portfolio, while leading cross-functi...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$210K - $230K *

Accelerate progress at the forefront of clinical supply chain management, leading strategic initiatives to ensure seamless delivery of investigational products for global trials while collaborating ac...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Innovate data solutions by developing complex reports and analyses to support senior management and client needs. Collaborate with teams to enhance data literacy and provide technical guidance across...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$123K - $157K *

Lead the charge in global sourcing strategies for plastics, driving supplier relationships and cost optimization while ensuring supply continuity and supporting new product introductions across manufa...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Unlock your potential by driving enterprise growth in healthcare. Join a dynamic team focused on building relationships with health systems and provider organizations, leveraging a robust support engi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $138K *

Lead the charge in defining and executing a comprehensive product strategy, driving value across product portfolios. Collaborate with key stakeholders to align strategic vision while overseeing perfor...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Elevate senior care by delivering high-quality, relationship-based primary care. Enjoy autonomy and flexibility while collaborating with a dedicated team to improve patient outcomes and enhance the li...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the Community Living Center, overseeing patient care and safety. Collaborate with an interdisciplinary team to monitor productivity, drive strategic planning, and ensure compliance with quality s...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join a dynamic team as an Associate Optometrist, providing high-quality patient care with professional autonomy. Enjoy flexible scheduling and access to advanced technology in a supportive environment...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$78K - $128K *

Optimize patient recovery through tailored physical therapy programs, collaborating with interdisciplinary teams to enhance mobility, relieve pain, and improve overall health outcomes for diverse popu...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $116K *

Unlock potential as a mid-level actuarial analyst, applying statistical techniques to enhance insurance pricing, claims analysis, and profitability studies while progressing through the Actuarial Exec...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$245K *

Partner with us to redefine virtual primary care, delivering exceptional patient services through innovative telehealth solutions. Join our dedicated team to enhance health accessibility and effective...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $245K *

Join a team that's dedicated to providing expert employment counsel across a global workforce. You'll partner with business leaders to navigate complex employment issues, ensuring sound legal advice t...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Accelerate growth by coaching franchise owners in sales strategies, optimizing processes, and enhancing customer acquisition. Collaborate cross-functionally to develop training programs that foster a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$110K - $125K *

Elevate healthcare operations by leading credentialing and medical staff services across multiple states. Drive compliance, streamline onboarding, and enhance workflows to support over 200 professiona...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Lead the charge in driving sales growth by engaging independent physician practices. Utilize your expertise in full-cycle sales to build relationships, conduct virtual demos, and collaborate with team...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $138K *

Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$107K - $180K *

Join a team that's redefining API integration! Leverage your technical expertise to guide partners through the integration lifecycle, ensuring seamless onboarding and successful implementations while...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$95K - $130K *

Lead the charge in backlog management and agile ceremonies, translating stakeholder needs into prioritized tasks. Collaborate across squads to ensure delivery quality and stakeholder satisfaction whil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Make your mark at a leading healthcare organization, delivering high-quality, person-centered care in skilled nursing facilities. Collaborate with teams to improve health outcomes while enjoying auton...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.