Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$160K - $180K *

Join a team that's driving growth in Life Sciences by managing key client relationships and delivering innovative solutions. You'll oversee the entire sales process, collaborating with experts to achi...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$77K - $121K *

Unlock your potential as you lead organic social strategy, engage millions, and shape brand voice across platforms. Collaborate with creative teams to drive impactful content and community engagement...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Transform data operations by leading our Snowflake platform migration, ensuring security, reliability, and cost efficiency while collaborating across teams to standardize practices and enhance data ma...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$105K - $120K *

Engage with public health labs to enhance customer satisfaction and drive sales. Collaborate with cross-functional teams to execute market strategies and foster relationships with key opinion leaders...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $205K *

Transform sales strategies by driving key account growth, building relationships, and executing plans for a new kidney transplant product. Collaborate cross-functionally to ensure optimal market acces...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$172K - $210K *

Architect and lead customer-focused application development initiatives, translating business needs into robust software solutions. Leverage modern technologies and AI tools to ensure high-quality, se...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Drive impactful gene editing projects by leading client programs and cross-functional teams from initiation to closure, ensuring alignment on scope, timelines, and deliverables while managing risks an...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Lead the charge in architectural innovation and technical strategy across systems. Shape long-term solutions, drive frontend performance, and foster cross-functional collaboration to enhance user expe...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Engage with a talented team to drive growth and innovation in pharma sales. Own the sales cycle from strategic prospecting to closing high-impact deals, while developing key relationships that enhance...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Champion the management of complex liability claims, ensuring thorough investigations, negotiations, and settlements. Collaborate with internal and external stakeholders to maintain high standards of...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $120K *

Accelerate progress at the intersection of media and healthcare by leading integrated planning and strategy for pharmaceutical clients. Drive impactful engagement initiatives while mentoring a talente...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join our team to oversee the comprehensive operations of a PACE program, ensuring effective service delivery, compliance, and financial performance while fostering a culture of innovation and teamwork...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential by driving sales of innovative pulmonary solutions. Collaborate with diverse stakeholders to enhance patient care and achieve sales targets in a dynamic healthcare environment. J...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by delivering exceptional patient care and pharmacy services. As a vital healthcare professional, you'll fill prescriptions, counsel patients, and support community wellness initiativ...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Lead advanced troubleshooting and repair of medical equipment, ensuring customer satisfaction through service excellence. Collaborate with teams, mentor junior engineers, and drive initiatives to enha...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$106K - $176K *

Optimize enterprise database services in a secure hybrid-cloud environment. As a senior technical resource, ensure performance, security, and reliability while supporting cloud adoption and modernizat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$146K - $189K *

Partner with us to enhance our community health provider network. Leverage your expertise in provider relations and network management to drive growth, improve access to care, and support our mission...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$122K - $214K *

Support the development of innovative risk strategies by leveraging analytical skills and industry expertise. Collaborate across teams to influence decisions and enhance underwriting practices, drivin...

Des Moines, IARemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $100K *

Shape the future of healthcare sales by driving product promotion and building relationships with healthcare professionals. Utilize strategic planning and effective presentations to exceed sales goals...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Unlock integrated marketing strategies to drive growth through data-driven campaigns, digital activation, and thought leadership, ensuring alignment with sales and operational goals for measurable bus...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$122K - $180K *

Accelerate product development by defining, designing, and prototyping features for partner integrations, leveraging AI tools and user feedback to enhance payment processing solutions and maintain com...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $120K *

Transform your career by joining a dynamic IT Services team as a ServiceNow System Administrator. Collaborate with stakeholders to design and enhance enterprise solutions, ensuring optimal performance...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$96K - $120K *

Partner with cross-functional teams to drive successful integrations, ensuring best practices and client satisfaction. Become the internal expert on data management while leading technical relationshi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$145K - $220K *

Drive impactful product marketing strategies for proactive security solutions, guiding market positioning, launches, and customer engagement. Collaborate with cross-functional teams to shape product d...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Empower the execution of CMC strategies by collaborating across teams to enhance production, streamline operations, and drive commercial success for innovative therapeutics and diagnostics, ensuring a...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.