Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$100K - $120K *

Lead the charge in enhancing rehabilitation operations across multiple facilities. Drive clinical excellence, manage staff, and ensure compliance while fostering a supportive environment for both pati...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Pioneer global payroll operations, ensuring compliance and accuracy across multiple regions. Lead payroll processes and provide exceptional support as you contribute to the team’s expansion and effici...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate data engineering capabilities by designing robust ETL/ELT workflows, ensuring data quality, and implementing scalable solutions on AWS and Kubernetes. Collaborate with teams to optimize perfor...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$71K - $113K *

Engineer innovative ERP solutions by customizing modules, integrating features, and enhancing system performance. Collaborate with stakeholders to align business objectives with technical capabilities...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Champion growth by building strategic relationships and driving sales in the Healthcare sector. Leverage AI solutions to enhance customer engagement and achieve revenue targets while collaborating wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Take ownership of driving sales growth by identifying client needs and presenting tailored solutions. Collaborate with stakeholders to enhance market share and build lasting relationships through effe...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $140K *

Drive compliance excellence as a Senior Compliance Program Manager, overseeing complex initiatives across enterprise and federal environments. Collaborate with cross-functional teams to ensure audit r...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$171K - $190K *

Unlock potential by leading the design and implementation of scalable data platforms. Drive innovation in cloud data architecture and pipeline automation, collaborating across teams to deliver impactf...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $85K *

Elevate your career by analyzing complex litigation claims, ensuring timely resolutions, and delivering exceptional client service in a dynamic, supportive environment. Join a global leader committed...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$245K - $265K *

Build impactful partnerships with Medical Experts to enhance neurology care. Drive strategic insights and collaboration across teams, influencing marketing and education initiatives while engaging wit...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $155K *

Champion product marketing by owning positioning, messaging, and go-to-market strategies. Collaborate across teams to drive product launches, enhance sales readiness, and build a high-performing marke...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $190K *

Join a team that's driving architectural excellence and AI adoption. You'll optimize cloud systems, enhance data processing, and lead engineering teams to innovate and scale efficiently, ensuring robu...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $110K *

Transform field support by leveraging expertise to enhance customer satisfaction, drive product improvements, and lead training initiatives. Collaborate with R&D and field teams to ensure optimal perf...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform consumer growth by building AI-driven acquisition strategies. Lead paid and organic channels, manage a $5M+ budget, and prototype new revenue streams while developing a high-output team to d...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$200K *

Lead the charge in driving enterprise growth marketing strategies, optimizing pipeline performance, and orchestrating cross-functional initiatives to scale demand generation and revenue outcomes acros...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $130K *

Join a team that's dedicated to driving legal excellence and risk management. As a Senior Commercial Paralegal, you'll draft and negotiate agreements, coordinate legal responses, and support cross-dep...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$120K - $145K *

Drive AI transformation by bridging client needs and technology capability, orchestrating cross-functional teams to innovate finance processes, optimize workflows, and deliver measurable enterprise va...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Champion seamless data integration across IT systems by leading complex projects, troubleshooting issues, and optimizing performance. Leverage your expertise in integration technologies to ensure data...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a dynamic team to design and develop innovative software applications, enhancing internal processes and client interactions. Leverage your technical expertise in Salesforce, SQL, and Agile method...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $150K *

Champion continuous improvement initiatives by optimizing processes and products across the organization. Lead cross-functional teams to enhance operational efficiency, quality, and customer experienc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's leading Medicaid programs and initiatives, driving operational excellence and policy implementation while managing multidisciplinary teams and enhancing organizational performance a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$180K - $275K *

Unlock potential by defining and driving the technical vision and product strategy for Next-Gen SIEM and Log Management products, ensuring alignment with market needs and customer motivations while fo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$66K - $128K *

Transform sales operations by owning CRM administration, building dashboards, and automating processes. Collaborate with teams to enhance technology adoption and streamline workflows, ensuring effecti...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$134K - $231K *

Shape the future of global supply chain operations by providing strategic legal support, drafting contracts, and ensuring compliance with environmental and safety regulations. Collaborate across funct...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$162K - $224K *

Transform healthcare operations by leveraging your expertise to drive efficiency and improve outcomes. Engage with clients to analyze needs, manage projects, and lead teams in delivering sustainable p...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.