Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$200K - $350K *

Transform actuarial services by validating third-party data, establishing loss assumptions, and independently reserving gross/ceded/net. Lead technical support for the Reserve Committee while enhancin...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to enhancing contract management and customer experience. Leverage your expertise in contract administration and customer service to streamline processes and ensure compli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $106K *

Analyze and optimize Amazon DSP and paid search campaigns to drive results across Retail Media. Leverage data insights to enhance performance, ensuring KPI excellence while managing fast-paced, multif...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Lead the implementation and management of client Speaker Bureau operations, ensuring successful educational programs in the pharmaceutical sector. Collaborate with cross-functional teams to exceed cli...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Manage and optimize Epic Professional Billing workflows, focusing on Claims and Remittance. Serve as a key resource for end-users, troubleshooting issues and enhancing billing processes to ensure accu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team as you oversee security initiatives across IT, AI, and cloud environments. Collaborate with engineers and R&D to enhance compliance, automate processes, and drive secure solutions...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$135K - $160K *

Lead the charge in transforming legal operations by advising corporate legal departments on strategy, technology, and process improvements. Drive complex engagements, build trusted relationships, and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Join us to validate complex workflows in Privileged Access Management, ensuring high standards for reliability and security across cloud integrations and enterprise environments. Collaborate with engi...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $216K *

Join a dynamic team to lead technology consulting projects in biopharma, ensuring successful implementation of patient services solutions. Collaborate with clients and cross-functional teams to drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Optimize property performance through strategic maintenance leadership, driving safety culture and sustainability. This impactful role necessitates technical expertise and frequent travel to ensure ex...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $110K *

Transform Medicaid programs by managing initiatives, coordinating stakeholders, and driving quality improvements. Leverage your expertise to implement policies and enhance operational efficiency in a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$236K - $354K *

Elevate clinical operations by leading global study management, driving strategic vision, and ensuring high-quality trial execution. Collaborate across teams to optimize resources and foster a culture...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Accelerate growth through strategic demand generation and integrated marketing campaigns. Collaborate with Sales and Product teams to optimize the pipeline, drive revenue, and enhance customer engagem...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$197K - $257K *

Drive your career forward as a strategic People leader, aligning talent strategies with business goals, coaching executives, and fostering organizational effectiveness for impactful growth and develop...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $224K *

Elevate healthcare solutions by driving business development in neurodegenerative disease pathways. Collaborate with health systems and stakeholders to identify needs, develop strategies, and create i...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$107K - $160K *

Lead the charge in providing strategic financial insights for skilled nursing clients. Oversee high-quality reporting, mentor teams, and drive operational improvements to ensure long-term financial st...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Grow your career with an influential role in customer success, fostering strong relationships and driving client satisfaction post-sale while managing renewals and growth opportunities in the health c...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Drive comprehensive legal support across diverse business functions, managing contracts, insurance, and litigation. Collaborate with cross-functional teams to ensure compliance and facilitate growth i...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $165K *

Lead transformative consulting engagements to enhance healthcare coding and middle revenue cycle processes, driving operational efficiency, compliance, and financial performance across diverse project...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Business Services

$180K - $200K *

Champion commercial manufacturing excellence by leading technical operations, ensuring on-time delivery of drug products and APIs, and collaborating with regulatory teams to meet compliance and perfor...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$116K - $145K *

Join a dynamic team to design and implement cloud security solutions, enhancing information security and compliance while mitigating cyber threats across the organization. Drive innovation and improve...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Transform Drug Supply Chain Operations by leading cross-functional teams to establish reliable planning cadences and robust processes, ensuring continuous delivery of medication while driving efficien...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.