Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$80K - $95K *

Join a team that's redefining healthcare recruiting by building and scaling a high-impact Direct Employer business through innovative sales strategies and cutting-edge technology, driving growth direc...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$90K - $110K *

Innovate technical SEO strategies to enhance global web performance, ensuring optimal search visibility and user experience. Collaborate with cross-functional teams to identify and resolve technical i...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$73K - $100K *

Elevate workforce planning by transforming data into impactful insights. Partner with leaders to build strategic forecasting tools and measure performance metrics, contributing to operational efficien...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $185K *

Join a dynamic team to define and lead product strategy for Family Building Navigation, enhancing member engagement through innovative digital experiences and personalized support while collaborating...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$105K - $129K *

Elevate client engagement through data-driven insights! As a Senior Analyst, you'll analyze performance metrics, enhance marketing strategies, and drive client retention, ensuring impactful decisions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$92K - $120K *

Join a dynamic team as a Medical Claims Auditor, ensuring compliance and integrity in healthcare payments. Collaborate with cross-functional teams to identify fraud, waste, and abuse while leveraging...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Join a dynamic team to drive growth in the pharmaceutical sector, leveraging your expertise to build relationships, win new business, and deliver impactful solutions that enhance brand performance and...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Transform your career as a strategic finance leader, driving financial operations and strategic planning. Own the P&L, balance sheet, and cash flow while partnering with executives to shape growth and...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$84K - $128K *

Join a team that's dedicated to resolving complex billing and contract cases for Mid-Market and Commercial accounts. You'll collaborate cross-functionally to enhance customer satisfaction and streamli...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$112K - $195K *

Accelerate progress at digital modernization initiatives by leading human-centered product design. Collaborate with diverse teams to enhance workflows, automate processes, and create AI-enabled experi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Drive procurement excellence by supporting cross-functional teams in vendor governance and sourcing. Leverage analytical skills to improve processes and mitigate risks while crafting strategic solutio...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Transform customer engagements by owning solution direction across multiple accounts. Drive platform adoption, orchestrate delivery teams, and shape opportunities to ensure measurable value and long-t...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$215K - $250K *

Pioneer your career by leading a dynamic sales team focused on Labor and Public Sector markets. Drive growth, mentor talent, and execute strategic initiatives to exceed revenue goals while building im...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $140K *

Shape the future of public service by leading technology consulting projects that enhance operational efficiency and strategic goals for state and local agencies, ensuring compliance and delivering im...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$170K - $200K *

Elevate our Enterprise business by building impactful relationships with brokers and consultants. Drive engagement strategies, generate new business opportunities, and enhance BetterHelp's presence in...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Empower your career by leading a high-performing sales team to drive profitable growth in the healthcare sector. Develop and execute strategic sales initiatives, foster client relationships, and ensur...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$190K - $205K *

Advance your career by driving growth in healthcare through impactful sales presentations and relationship management with hospital stakeholders. Collaborate across teams to optimize customer engageme...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Shape the future of pharmacy software by leading product strategy, managing cross-functional teams, and driving improvements in patient outcomes and business results through innovative product managem...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Drive impactful solutions as a Healthcare Technology Manager, optimizing Epic Patient Access systems. Collaborate with clients and teams to enhance workflows and deliver sustainable results in a suppo...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Analyze and optimize workforce management strategies across multiple business lines, translating complex forecasts into actionable capacity plans and financial models while collaborating with executiv...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $151K *

Transform your career by leading pharmacy operations, ensuring patient safety, and enhancing customer service. Collaborate with a dedicated team to drive growth and improve healthcare outcomes in a dy...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Join a dynamic team to drive commercial performance and enhance patient access through strong relationships with healthcare providers, executing strategic business plans in a pivotal role focused on i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $250K *

Lead the charge in scientific dialogue with key healthcare professionals, providing critical insights and support within your therapeutic area. Utilize your expertise to enhance patient outcomes and f...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $187K *

Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.