Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$115K - $125K *

Elevate virtual health services by leading strategic initiatives, enhancing patient experiences, and driving operational excellence. Collaborate across teams to implement innovative care models and en...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Champion social strategy and community engagement, driving impactful growth across multiple channels. Lead a dynamic team to create culturally relevant content, leveraging AI for efficiency and innova...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $215K *

Unlock potential by leading the development of a virtual engagement team to enhance outreach to healthcare professionals, ensuring effective collaboration with field sales and marketing for optimal im...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $150K *

Elevate healthcare performance by leading analytics-driven consulting engagements. Collaborate with clients to identify needs, deliver insights, and implement solutions while managing project economic...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $130K *

Unlock your potential by leading customer projects, ensuring seamless communication, and driving success in healthcare solutions. Collaborate with diverse teams to enhance client satisfaction and oper...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Transform customer success and support by leading a dynamic team to enhance retention and expansion strategies. Collaborate with executives to build infrastructure and drive growth for 2,100+ accounts...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$134K - $306K *

Elevate customer engagement by developing and executing strategic study plans, leading cross-functional teams, and ensuring successful project delivery in the rare disease therapeutic area...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic team to drive sales growth in the beauty sector, identifying new opportunities and fostering relationships with key retailers. Collaborate across departments to shape strategies that am...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $110K *

Advance quality assurance efforts by designing and executing tests for backend systems and APIs, ensuring data integrity and performance across cloud environments. Collaborate with engineers to enhanc...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$175K - $200K *

Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$105K - $115K *

Optimize medical device utilization in health systems by leveraging expertise in cardiovascular, interventional radiology, and general surgery. Collaborate with stakeholders to drive cost reduction an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Empower clients by providing remote counseling services, addressing diverse mental health concerns through structured video sessions while ensuring compliance with ethical standards and maintaining cl...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Lead the charge in providing remote counseling services to clients facing mental health challenges. Utilize your expertise to conduct intake sessions, maintain records, and ensure client safety while...

Johnston, IARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Empower clients by providing telehealth counseling for mental health issues. Engage in intake, documentation, and follow-up to support individuals facing anxiety, depression, and trauma, ensuring a co...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Drive client growth by enhancing software adoption and satisfaction. Collaborate with sales and success teams to implement strategies, facilitate demos, and manage client relationships, ensuring long...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Join us to empower community coalitions in preventing youth substance use. As a Project Officer, you'll manage grants, provide technical assistance, and enhance local capacities, all while collaborati...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $90K *

Grow your career with a dynamic team providing intensive outpatient therapy for older adults. Collaborate with healthcare professionals to deliver compassionate mental health support, focusing on grou...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $167K *

Drive strategic initiatives in Medicare Advantage provider networks, analyzing data and collaborating with leadership to enhance performance and achieve goals. Lead complex projects from inception to...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $85K *

Shape the future of patient care by leading an outpatient therapy team. Collaborate with staff to enhance service delivery and drive business growth while preparing for advancement to center manager...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in financial strategy and operational excellence, driving growth and sustainability for a mission-driven organization. Collaborate with leadership to implement innovative solutions and...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Accelerate your career by driving revenue growth with enterprise clients. Leverage your sales expertise in the fashion industry to build relationships, identify needs, and deliver tailored solutions t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join our team to drive innovation in eye care by presenting scientific insights, fostering relationships with medical experts, and influencing strategies to enhance patient outcomes through evidence-b...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a team that's dedicated to enhancing compliance excellence through strategic oversight of operations, risk management, and audit processes. Collaborate with leadership to drive regulatory complia...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Shape compliance excellence by overseeing post-closing functions, managing risks, and driving continuous improvement. Collaborate with stakeholders to ensure adherence to regulations and enhance the C...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.