Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$190K - $235K *

Transform the future of digital marketing strategy by leading cross-functional initiatives that align brand objectives with innovative digital capabilities, ensuring a cohesive and effective customer...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform pharmacy outcomes by leading managed care initiatives that optimize clinical programs, enhance stakeholder collaboration, and drive cost efficiencies in pharmacy benefit management...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion quality control excellence by leading teams in Chemistry, Virology, and Immunochemistry. Ensure compliance with regulatory standards while driving process improvements and supporting cross-fu...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Drive critical initiatives by navigating ambiguity, building effective operating models, and ensuring measurable outcomes in a dynamic environment. Engage with leadership to implement AI solutions and...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $90K *

Champion project success by managing timelines, resources, and stakeholder communication. Drive seamless implementation experiences while collaborating with cross-functional teams to deliver value-dri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $200K *

Elevate your career by driving sales strategy and execution for a dynamic SaaS portfolio. Lead a high-performing team to achieve revenue growth, optimize pipeline management, and enhance customer acqu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$150K - $180K *

Engineer cutting-edge blockchain infrastructure for financial markets. Drive architecture, design proofs of concept, and ensure interoperability while collaborating with teams to meet institutional re...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$124K - $140K *

Accelerate your career by managing sales efforts for innovative products in gastroenterology. Cultivate relationships with healthcare professionals while driving business growth and addressing technic...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$156K - $260K *

Empower cyber defense initiatives by designing, implementing, and optimizing advanced security solutions. Lead investigations, mentor teams, and enhance detection capabilities to proactively mitigate...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Partner with us to ensure the quality and reliability of our web-based administrative solutions. Collaborate with cross-functional teams to validate features, identify defects, and maintain comprehens...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $175K *

Unlock your potential as a hands-on leader in customer service operations, driving performance and quality across teams. Collaborate with cross-functional partners to enhance processes and empower you...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$70K - $100K *

Join a team that's dedicated to optimizing Epic Resolute Professional Billing. Support daily operations, troubleshoot issues, and enhance workflows while collaborating with analysts and users to ensur...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to enhancing client experiences through exceptional facility management. Oversee multiple locations, collaborate on strategic initiatives, and ensure a welcoming atmospher...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $200K *

Unlock potential by defining and guiding enterprise architecture, integrating cloud, infrastructure, and security to support business priorities. Lead modernization efforts and influence cross-functio...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$109K - $164K *

Join a dynamic team providing in-home care, conducting assessments, managing acute conditions, and collaborating with care teams. Enjoy a rewarding environment with no nights, weekends, or holidays wh...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate within a dynamic team, driving impactful projects and solutions that enhance operational efficiency and foster growth across multiple departments. Your expertise will shape strategic initiati...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Partner with us to enhance veterinary medical support through education, training, and product expertise. Engage with veterinarians and sales teams to ensure compliance and promote American Regent Ani...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Manage territory business plans to drive sales performance, engage healthcare providers, and support product launches. Collaborate with cross-functional teams to optimize patient access and ensure com...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock product potential by leading the development of innovative food safety solutions. Collaborate with cross-functional teams to address complex industry challenges and drive scalable product strat...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $220K *

Drive clinical excellence by providing medical expertise across therapeutic areas, ensuring safety and integrity in clinical trials. Collaborate with project teams and senior management to enhance cli...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$62K - $112K *

Transform member engagement by proactively addressing concerns, coordinating solutions, and enhancing satisfaction. Collaborate with cross-functional teams to drive improvements and ensure a seamless...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$110K - $130K *

Elevate patient care by overseeing medication safety and efficacy. Collaborate with healthcare teams to ensure accurate prescriptions, resolve drug-related issues, and enhance patient outcomes through...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$228K - $342K *

Drive technical strategies and influence enterprise executives to enhance identity security. Mentor teams, shape product direction, and engage with Fortune 500 leaders to tackle complex security chall...

RemoteRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$275K - $335K *

Launch innovative marketing strategies to create a new category in veterinary medicine. Collaborate with teams to build brand credibility and consumer awareness for a groundbreaking longevity drug for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.